Signaling pathways in cutaneous wound healing

J 2022

Signaling pathways in cutaneous wound healing

KRIŽANOVÁ, Oľga, Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ, Amir SAMADIAN et. al.

Basic information

Original name

Signaling pathways in cutaneous wound healing

Authors

KRIŽANOVÁ, Oľga (703 Slovakia, belonging to the institution), Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ (703 Slovakia, belonging to the institution), Amir SAMADIAN (364 Islamic Republic of Iran, belonging to the institution) and Petr BABULA (203 Czech Republic, guarantor, belonging to the institution)

Edition

Frontiers in Physiology, Lausanne, FRONTIERS MEDIA SA, 2022, 1664-042X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.000

RIV identification code

RIV/00216224:14110/22:00129728

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3389/fphys.2022.1030851

UT WoS

000895789500001

Keywords in English

wound healing; gasotransmitters; calcium; hydrogen peroxide; diabetes mellitus

Abstract

V originále

Wound healing is a very complex process, where variety of different pathways is activated, depending on the phase of healing. Improper or interrupted healing might result in development of chronic wounds. Therefore, novel approaches based on detailed knowledge of signalling pathways that are activated during acute or chronic cutaneous wound healing enables quicker and more effective healing. This review outlined new possibilities of cutaneous wound healing by modulation of some signalling molecules, e.g., gasotransmitters, or calcium. Special focus is given to gasotransmitters, since these bioactive signalling molecules that can freely diffuse into the cell and exert antioxidative effects. Calcium is an important booster of immune system and it can significantly contribute to healing process. Special interest is given to chronic wounds caused by diabetes mellitus and overcoming problems with the inflammation.

Links

NU21-09-00541, research and development project

Name: Role oxidativního stresu při hojení dekubitů u pacientů s míšní lézí

Investor: Ministry of Health of the CR, Subprogram 1 - standard

Citovat

KRIŽANOVÁ, Oľga, Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ, Amir SAMADIAN and Petr BABULA. Signaling pathways in cutaneous wound healing. Frontiers in Physiology. Lausanne: FRONTIERS MEDIA SA, 2022, vol. 13, November 2022, p. 1-11. ISSN 1664-042X. Available from: https://dx.doi.org/10.3389/fphys.2022.1030851.

@article{2248069,
   author = {Križanová, Oľga and Penesova, Adela and Sokol, Jozef and Hokynková, Alica and Samadian, Amir and Babula, Petr},
   article_location = {Lausanne},
   article_number = {November 2022},
   doi = {http://dx.doi.org/10.3389/fphys.2022.1030851},
   keywords = {wound healing; gasotransmitters; calcium; hydrogen peroxide; diabetes mellitus},
   language = {eng},
   issn = {1664-042X},
   journal = {Frontiers in Physiology},
   title = {Signaling pathways in cutaneous wound healing},
   url = {https://www.frontiersin.org/articles/10.3389/fphys.2022.1030851/full},
   volume = {13},
   year = {2022}
}

TY  - JOUR
ID  - 2248069
AU  - Križanová, Oľga - Penesova, Adela - Sokol, Jozef - Hokynková, Alica - Samadian, Amir - Babula, Petr
PY  - 2022
TI  - Signaling pathways in cutaneous wound healing
JF  - Frontiers in Physiology
VL  - 13
IS  - November 2022
SP  - 1-11
EP  - 1-11
PB  - FRONTIERS MEDIA SA
SN  - 1664042X
KW  - wound healing
KW  - gasotransmitters
KW  - calcium
KW  - hydrogen peroxide
KW  - diabetes mellitus
UR  - https://www.frontiersin.org/articles/10.3389/fphys.2022.1030851/full
N2  - Wound healing is a very complex process, where variety of different pathways is activated, depending on the phase of healing. Improper or interrupted healing might result in development of chronic wounds. Therefore, novel approaches based on detailed knowledge of signalling pathways that are activated during acute or chronic cutaneous wound healing enables quicker and more effective healing. This review outlined new possibilities of cutaneous wound healing by modulation of some signalling molecules, e.g., gasotransmitters, or calcium. Special focus is given to gasotransmitters, since these bioactive signalling molecules that can freely diffuse into the cell and exert antioxidative effects. Calcium is an important booster of immune system and it can significantly contribute to healing process. Special interest is given to chronic wounds caused by diabetes mellitus and overcoming problems with the inflammation.
ER  -

KRIŽANOVÁ, Oľga, Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ, Amir SAMADIAN and Petr BABULA. Signaling pathways in cutaneous wound healing. \textit{Frontiers in Physiology}. Lausanne: FRONTIERS MEDIA SA, 2022, vol.~13, November 2022, p.~1-11. ISSN~1664-042X. Available from: https://dx.doi.org/10.3389/fphys.2022.1030851.

Detailed Information on Publication Record