J 2023

The future for the application of fibroblast growth factor 2 in modern wound healing

HOLOUBEK, Jakub, Břetislav LIPOVÝ, Martin KNOZ, Tomáš KEMPNÝ, Radka CHALOUPKOVÁ et. al.

Basic information

Original name

The future for the application of fibroblast growth factor 2 in modern wound healing

Authors

HOLOUBEK, Jakub (203 Czech Republic, belonging to the institution), Břetislav LIPOVÝ (203 Czech Republic, belonging to the institution), Martin KNOZ (203 Czech Republic, guarantor), Tomáš KEMPNÝ (203 Czech Republic), Radka CHALOUPKOVÁ (203 Czech Republic, belonging to the institution), Jiří DAMBORSKÝ (203 Czech Republic, belonging to the institution) and Lucy VOJTOVÁ (203 Czech Republic, belonging to the institution)

Edition

BURNS, OXFORD, ELSEVIER SCI LTD, 2023, 0305-4179

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.700 in 2022

RIV identification code

RIV/00216224:14110/23:00134621

Organization unit

Faculty of Medicine

UT WoS

000954799500001

Keywords in English

fibroblast growth factor 2; wound healing

Tags

Tags

International impact, Reviewed
Změněno: 26/1/2024 10:43, Mgr. Tereza Miškechová

Abstract

V originále

Representatives of the fibroblast growth factor (FGF) family regulate a wide range of biological functions important for every phase of wound healing, such as cell proliferation, migration, and differentiation. The name of the family is derived from the primary assumption that FGF proteins (FGF1 and FGF2) are important for promoting fibroblast migration and proliferation. Today, FGFs are known to intervene in a wide range of biological functions of various cell populations. Their function is mediated by binding to specific receptors (tyrosine-kinase receptors), which leads to their activation and transmembrane signal transduction into the cell.

Links

NU22-08-00454, research and development project
Name: Biomimetický vícevrstevný buněčný nosič čtvrté generace pro jednokrokovou úplnou náhradu kůže: z laboratoře do klinické aplikace
Investor: Ministry of Health of the CR, Subprogram 1 - standard