J 2022

Impact of SARS-CoV-2 variants on the incidence of paediatric inflammatory multisystem syndrome (PIMS-TS)

DAVID, Jan, Ondrej HRADSKY, Petr JABANDŽIEV, Eva KLASKOVA, Helena JIRINCOVA et. al.

Basic information

Original name

Impact of SARS-CoV-2 variants on the incidence of paediatric inflammatory multisystem syndrome (PIMS-TS)

Authors

DAVID, Jan (203 Czech Republic, guarantor), Ondrej HRADSKY (203 Czech Republic), Petr JABANDŽIEV (203 Czech Republic, belonging to the institution), Eva KLASKOVA (203 Czech Republic), Helena JIRINCOVA (203 Czech Republic) and Jan LEBL (203 Czech Republic)

Edition

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, HOBOKEN, WILEY, 2022, 1034-4810

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30209 Paediatrics

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 1.700

RIV identification code

RIV/00216224:14110/22:00128210

Organization unit

Faculty of Medicine

UT WoS

000862425800040

Keywords in English

SARS-CoV-2 variants; paediatric inflammatory multisystem syndrome

Tags

Tags

International impact, Reviewed
Změněno: 2/2/2023 14:40, Mgr. Tereza Miškechová

Abstract

V originále

In Spring 2020, following temporary success during the first wave of the world-wide pandemic of the novel 2019 coronavirus disease (COVID-19) with very few positive cases, the Czech Republic (CZ) subsequently suffered from one of the highest incidences of individuals who tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In March 2022, the cumulative number of positive cases reached almost 3.5 million (34.1% of the population). Individual pandemic waves in CZ were characterised with predominant genetic variants, namely: B.1.258 in the second wave in late 2020, alpha (B.1.1.7) in the third wave in early 2021, delta (B.1.617.2) in the fourth wave in late 2021, and finally Omicron (B.1.1.529) in the last wave in early 2022. At the same time, paediatricians faced paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). The incidence of PIMS-TS among SARS-CoV-2 positive children varies at around 0.3:1000. However, no data have been published on the impact of variants or lineages of SARS-CoV-2 on the occurrence of PIMS-TS. The aim of this study was to analyse the association between SARS-CoV-2 lineage and the incidence of PIMS-TS cases.