NOVOTNA, Veronika, R. CIPIN, Dalibor CERVINKA, Zdeněk STÁREK and Martin PEŠL. Numerical Modeling of Electroporation Process Using Endocardial Catheter. Online. In Jarm, T., Cvetkoska, A., Mahnič-Kalamiza, S., Miklavcic, D. 8th European Medical and Biological Engineering Conference. EMBEC 2020. IFMBE Proceedings. 80th ed. Switzerland: Springer Nature Switzerland ag, 2021, p. 896-904. EMBEC. ISBN 978-3-030-64609-7. Available from: https://dx.doi.org/10.1007/978-3-030-64610-3_100.
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Basic information
Original name Numerical Modeling of Electroporation Process Using Endocardial Catheter
Authors NOVOTNA, Veronika, R. CIPIN, Dalibor CERVINKA, Zdeněk STÁREK (203 Czech Republic) and Martin PEŠL (203 Czech Republic, belonging to the institution).
Edition 80. vyd. Switzerland, 8th European Medical and Biological Engineering Conference. EMBEC 2020. IFMBE Proceedings, p. 896-904, 9 pp. EMBEC, 2021.
Publisher Springer Nature Switzerland ag
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
Publication form electronic version available online
WWW URL
RIV identification code RIV/00216224:14110/21:00128248
Organization unit Faculty of Medicine
ISBN 978-3-030-64609-7
Doi http://dx.doi.org/10.1007/978-3-030-64610-3_100
Keywords in English Electroporation Numerical modelling Endocardial catheter Heart
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 5/4/2023 08:29.
Abstract
This paper is about electroporation using an endocardial catheter. It is focused on numerical modeling of the electroporation process inspired by in vivo experiment. Two electroporation models are compared; model with electric conductivity dependent and independent on the electric field intensity. Further, it also demonstrates the effect of the flowing blood on obtained results. The electroporation effect in the homogeneous tissue is symmetrical unlike the effect in the inhomogeneous tissue. Blood flowing around the application electrode cools down the tissue but takes also majority of the current. The treatment has to be either longer or use higher voltage. The temperature was 40.7 °C for the model with electric conductivity dependent on the electric field intensity vs 45 °C with independent electric conductivity. Comparison of the simulated and measured data is not part of this paper.
Links
ROZV/23/LF9/2019, interní kód MUName: Mechanobiologické souvislosti účinku bronchodilatačních léčiv na vývoj získaných srdečních patologií - Analýza farmakologicky navozených změn kontrakce kardiomyocitů diferencovaných z kmenových buněk s pomocí mikroskopie atomárních sil
Investor: Ministry of Education, Youth and Sports of the CR, Internal development projects
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