Involvement of calcium signaling in different types of cell
death in cancer

J 2022

Involvement of calcium signaling in different types of cell death in cancer

BABULA, Petr and Oľga KRIŽANOVÁ

Basic information

Original name

Involvement of calcium signaling in different types of cell death in cancer

Authors

BABULA, Petr (203 Czech Republic, belonging to the institution) and Oľga KRIŽANOVÁ (703 Slovakia, guarantor)

Edition

Neoplasma, Bratislava, Slovenská akademie vied, 2022, 0028-2685

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.000

RIV identification code

RIV/00216224:14110/22:00129730

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.4149/neo_2022_220127N121

UT WoS

000833596300002

Keywords in English

calcium transport systems; cell death; cancer

Abstract

V originále

Programmed cell death is a basic feature of chemotherapeutic (and also radiotherapeutic) intervention. Induction of cell death in tumor cells aims to kill preferentially the tumor cells, with minimal impact on the normal cells. Although apoptosis is the most obvious type of cell death induced by chemotherapeutics, several other types can also be activated, especially in conditions, where cells are resistant to apoptosis induction. Calcium signaling was shown to play an indisputable role in the activation of different types of cell death. Local increase of the calcium in time and precise place of this increase is secured by calcium transport systems. In this review, we summarized the involvement of some calcium transport systems in apoptosis, autophagy, necroptosis, ferroptosis, and mitophagy during cancer development and treatment.

Links

NU21-09-00541, research and development project

Name: Role oxidativního stresu při hojení dekubitů u pacientů s míšní lézí

Investor: Ministry of Health of the CR, Subprogram 1 - standard

Citovat

BABULA, Petr and Oľga KRIŽANOVÁ. Involvement of calcium signaling in different types of cell death in cancer. Neoplasma. Bratislava: Slovenská akademie vied, 2022, vol. 69, No 2, p. 264-273. ISSN 0028-2685. Available from: https://dx.doi.org/10.4149/neo_2022_220127N121.

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   keywords = {calcium transport systems; cell death; cancer},
   language = {eng},
   issn = {0028-2685},
   journal = {Neoplasma},
   title = {Involvement of calcium signaling in different types of cell death in cancer},
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   volume = {69},
   year = {2022}
}

TY  - JOUR
ID  - 2249620
AU  - Babula, Petr - Križanová, Oľga
PY  - 2022
TI  - Involvement of calcium signaling in different types of cell death in cancer
JF  - Neoplasma
VL  - 69
IS  - 2
SP  - 264-273
EP  - 264-273
PB  - Slovenská akademie vied
SN  - 00282685
KW  - calcium transport systems
KW  - cell death
KW  - cancer
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N2  - Programmed cell death is a basic feature of chemotherapeutic (and also radiotherapeutic) intervention. Induction of cell death in tumor cells aims to kill preferentially the tumor cells, with minimal impact on the normal cells. Although apoptosis is the most obvious type of cell death induced by chemotherapeutics, several other types can also be activated, especially in conditions, where cells are resistant to apoptosis induction. Calcium signaling was shown to play an indisputable role in the activation of different types of cell death. Local increase of the calcium in time and precise place of this increase is secured by calcium transport systems. In this review, we summarized the involvement of some calcium transport systems in apoptosis, autophagy, necroptosis, ferroptosis, and mitophagy during cancer development and treatment.
ER  -

BABULA, Petr and Oľga KRIŽANOVÁ. Involvement of calcium signaling in different types of cell death in cancer. \textit{Neoplasma}. Bratislava: Slovenská akademie vied, 2022, vol.~69, No~2, p.~264-273. ISSN~0028-2685. Available from: https://dx.doi.org/10.4149/neo\_{}2022\_{}220127N121.

Detailed Information on Publication Record