Detailed Information on Publication Record
2023
Prognostic value of Doppler echocardiographic coronary flow velocity assessment at rest in elderly patients
ZAGATINA, Angela, Elena KALININA, Martin CAPRNDA, Ludovit GASPAR, Katarina GAZDIKOVA et. al.Basic information
Original name
Prognostic value of Doppler echocardiographic coronary flow velocity assessment at rest in elderly patients
Authors
ZAGATINA, Angela (guarantor), Elena KALININA, Martin CAPRNDA, Ludovit GASPAR, Katarina GAZDIKOVA, David ULLRICH (203 Czech Republic), Robert PROSECKÝ (203 Czech Republic, belonging to the institution), Luis RODRIGO and Peter KRUŽLIAK (703 Slovakia)
Edition
Acta Cardiologica, ABINGDON, TAYLOR & FRANCIS LTD, 2023, 0001-5385
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30201 Cardiac and Cardiovascular systems
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 1.600 in 2022
RIV identification code
RIV/00216224:14110/23:00130228
Organization unit
Faculty of Medicine
UT WoS
000863716700001
Keywords in English
Echocardiography; outcome; elderly; coronary flow; coronary Doppler
Tags
International impact, Reviewed
Změněno: 26/1/2024 10:48, Mgr. Tereza Miškechová
Abstract
V originále
Background Atherosclerosis and coronary artery disease (CAD) are a common condition and cause of death in the elderly population. There are difficulties with risk assessment in the elderly as the objectification of their symptomatic status can be challenging due to neuromuscular weakness, physical deconditioning or neurological, orthopaedic, peripheral vascular, or respiratory limitations. Non-invasive coronary artery velocity assessment by Doppler method at rest could be helpful in the elderly population. To evaluate the prognostic role of coronary artery ultrasound assessment in a non-selected elderly population in everyday clinical practice. Methods One hundred forty-five patients, aged >= 75years (99 women; 80 +/- 4 years), formed the study group. Left coronary artery flows were scanned in addition to conventional echocardiography. During a median follow-up of 26 months, 16 deaths and 2 non-fatal MI occurred. Results In multivariable analysis, maximal coronary velocity was the only independent predictor for mortality (heart rate [HR]: 1.02, 95%, CI: 1.01-1.04, p < .0005) and for mortality/MI (HR: 1.02, 95%, CI: 1.01-1.03, p < .0001). The value of 110 cm/s maximal coronary flow velocity (CFL) in the proximal segments of left arteries was the best predictor for death, sensitivity 50%, specificity 90%, p < .005. The annual mortality rate was 16.6% persons/year for patients with elevated CFL >= 110 cm/s. The value 81 cm/s was the best predictor for death/MI, sensitivity 61%, specificity 80%, p < .0005; annual mortality rate was 11.2% persons/year for patients with elevated CFL >= 81 cm/s (p < .0001). Conclusion Doppler CFL scanning during routine echocardiography is a feasible and valuable tool for assessment of short-term prognosis in elderly patients.