Detailed Information on Publication Record
2022
Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry
ZEYMER, Uwe, Peter LUDMAN, Nicolas DANCHIN, Petr KALA, Cecile LAROCHE et. al.Basic information
Original name
Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry
Authors
ZEYMER, Uwe (guarantor), Peter LUDMAN, Nicolas DANCHIN, Petr KALA (203 Czech Republic, belonging to the institution), Cecile LAROCHE, Chris P. GALE, Aldo P. MAGGIONI, Soraya SIABANI, Masoumeh SADEGHI, Ahmed WAFA, Stanislaw BARTUS and Franz WEIDINGER
Edition
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, OXFORD, OXFORD UNIV PRESS, 2022, 2048-8726
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30201 Cardiac and Cardiovascular systems
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 4.100
RIV identification code
RIV/00216224:14110/22:00128330
Organization unit
Faculty of Medicine
UT WoS
000799468700001
Keywords in English
Cardiogenic shock; ST-elevation myocardial infarction; Primary percutaneous coronary intervention; Registry; Reperfusion therapy
Tags
International impact, Reviewed
Změněno: 27/1/2023 13:54, Mgr. Tereza Miškechová
Abstract
V originále
Aims To determine the current state of the use of reperfusion and adjunctive therapies and in-hospital outcomes in European Society of Cardiology (ESC) member and affiliated countries for patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Methods and results ESC EurObservational Research Programme prospective international cohort study of admissions with STEMI within 24 h of symptom onset (196 centres; 26 ESC member and 3 affiliated countries). Of 11 462 patients enrolled, 448 (3.9%) had CS. Patients with compared to patients without CS, less frequently received primary percutaneous coronary intervention (PCI) (65.5% vs. 72.2%) and fibrinolysis (15.9% vs. 19.0), and more often had no reperfusion therapy (19.0% vs. 8.5%). Mechanical support devices (intraaortic ballon pump 11.2%, extracoporeal membrane oxygenation 0.7%, other 1.1%) were used infrequently in CS. Bleeding definition academic research consortium 2-5 bleeding complications (10.1% vs. 3.0%, P < 0.01) and stroke (4.2% vs. 0.9%, P < 0.01) occurred more frequently in patients with CS. In-hospital mortality was 10-fold higher (35.5% vs. 3.1%) in patients with CS. Mortality in patients with CS in the groups with PCI, fibrinolysis, and no reperfusion therapy were 27.4%, 36.6%, and 62.4%, respectively. Conclusion In this multi-national registry, patients with STEMI complicated by CS less frequently receive reperfusion therapy than patients with STEMI without CS. Early mortality in patients with CS not treated with primary PCI is very high. Therefore, strategies to improve clinical outcome in STEMI with CS are needed.