ZEYMER, Uwe, Peter LUDMAN, Nicolas DANCHIN, Petr KALA, Cecile LAROCHE, Chris P. GALE, Aldo P. MAGGIONI, Soraya SIABANI, Masoumeh SADEGHI, Ahmed WAFA, Stanislaw BARTUS and Franz WEIDINGER. Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry. EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. OXFORD: OXFORD UNIV PRESS, 2022, vol. 11, No 6, p. 481-490. ISSN 2048-8726. Available from: https://dx.doi.org/10.1093/ehjacc/zuac049.
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Basic information
Original name Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry
Authors ZEYMER, Uwe (guarantor), Peter LUDMAN, Nicolas DANCHIN, Petr KALA (203 Czech Republic, belonging to the institution), Cecile LAROCHE, Chris P. GALE, Aldo P. MAGGIONI, Soraya SIABANI, Masoumeh SADEGHI, Ahmed WAFA, Stanislaw BARTUS and Franz WEIDINGER.
Edition EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, OXFORD, OXFORD UNIV PRESS, 2022, 2048-8726.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.100
RIV identification code RIV/00216224:14110/22:00128330
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1093/ehjacc/zuac049
UT WoS 000799468700001
Keywords in English Cardiogenic shock; ST-elevation myocardial infarction; Primary percutaneous coronary intervention; Registry; Reperfusion therapy
Tags 14110211, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 27/1/2023 13:54.
Abstract
Aims To determine the current state of the use of reperfusion and adjunctive therapies and in-hospital outcomes in European Society of Cardiology (ESC) member and affiliated countries for patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Methods and results ESC EurObservational Research Programme prospective international cohort study of admissions with STEMI within 24 h of symptom onset (196 centres; 26 ESC member and 3 affiliated countries). Of 11 462 patients enrolled, 448 (3.9%) had CS. Patients with compared to patients without CS, less frequently received primary percutaneous coronary intervention (PCI) (65.5% vs. 72.2%) and fibrinolysis (15.9% vs. 19.0), and more often had no reperfusion therapy (19.0% vs. 8.5%). Mechanical support devices (intraaortic ballon pump 11.2%, extracoporeal membrane oxygenation 0.7%, other 1.1%) were used infrequently in CS. Bleeding definition academic research consortium 2-5 bleeding complications (10.1% vs. 3.0%, P < 0.01) and stroke (4.2% vs. 0.9%, P < 0.01) occurred more frequently in patients with CS. In-hospital mortality was 10-fold higher (35.5% vs. 3.1%) in patients with CS. Mortality in patients with CS in the groups with PCI, fibrinolysis, and no reperfusion therapy were 27.4%, 36.6%, and 62.4%, respectively. Conclusion In this multi-national registry, patients with STEMI complicated by CS less frequently receive reperfusion therapy than patients with STEMI without CS. Early mortality in patients with CS not treated with primary PCI is very high. Therefore, strategies to improve clinical outcome in STEMI with CS are needed.
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