ŠÍN, Petr, Alica HOKYNKOVÁ, Marie NOVÁKOVÁ, Hana PAULOVÁ, Petr BABULA, Andrea POKORNÁ, Lucie NÁRTOVÁ, Pavel COUFAL and Michal HENDRYCH. Can different type of the pressure ulcers debridement affect oxidative stress parameters? Ceska a slovenska neurologie a neurochirurgie. Prague: CZECH MEDICAL SOC, vol. 85, Supplementum 1, p. "S34"-"S37", 4 pp. ISSN 1210-7859. doi:10.48095/cccsnn2022S34. 2022.
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Basic information
Original name Can different type of the pressure ulcers debridement affect oxidative stress parameters?
Authors ŠÍN, Petr (203 Czech Republic, belonging to the institution), Alica HOKYNKOVÁ (703 Slovakia, guarantor, belonging to the institution), Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution), Hana PAULOVÁ (203 Czech Republic, belonging to the institution), Petr BABULA (203 Czech Republic, belonging to the institution), Andrea POKORNÁ (203 Czech Republic, belonging to the institution), Lucie NÁRTOVÁ (203 Czech Republic, belonging to the institution), Pavel COUFAL (203 Czech Republic, belonging to the institution) and Michal HENDRYCH (203 Czech Republic, belonging to the institution).
Edition Ceska a slovenska neurologie a neurochirurgie, Prague, CZECH MEDICAL SOC, 2022, 1210-7859.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30212 Surgery
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 0.500
RIV identification code RIV/00216224:14110/22:00129732
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.48095/cccsnn2022S34
UT WoS 000910094000001
Keywords in English pressure ulcer; pressure injury; debri-dement; Versajet hydrosurgery system; oxidative stress parameters
Tags 14110112, 14110229, 14110512, 14110515, 14110611, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 27/1/2023 14:17.
Abstract
Wound debridement is one of the crucial steps in wound bed preparation for surgical closure. Various debridement forms and tools can be employed. Aim: The prospective case series study aimed to compare the impact of two different types of debridement on oxidative stress parameters. Material and methods: This study included five patients with pressure ulcers of deep category various localisation. The wound was divided into halves. In one, the sharp debridement was performed, in the second Hydrosurgery Versajet (R) debridement was accomplished. Tissue, blood and urine samples were collected on days 0 and 7 after the surgery. Histopathological evaluation in tissue samples was performed. Oxidative stress parameters in plasma and urine were evaluated. Results: Diff erences in quality and quantity of granulation tissue between two types of debridement were found. An insignificant decrease of oxidative stress markers in blood plasma and urine 7 days after surgery were observed. Conclusions: Preliminary and pilot results suggest that the wound healing process is closely associated with markers of oxidative stress that are measurable in blood plasma and urine. These could be indicative of the healing process. A nonsignificant decrease was observed for all oxidative stress parameters on day 7 after the surgery. The pilot study will be followed by a detailed molecular bio logical analysis of tissue samples.
Links
NU21-09-00541, research and development projectName: Role oxidativního stresu při hojení dekubitů u pacientů s míšní lézí
Investor: Ministry of Health of the CR, Subprogram 1 - standard
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