Detailed Information on Publication Record
2022
Can different type of the pressure ulcers debridement affect oxidative stress parameters?
ŠÍN, Petr, Alica HOKYNKOVÁ, Marie NOVÁKOVÁ, Hana PAULOVÁ, Petr BABULA et. al.Basic information
Original name
Can different type of the pressure ulcers debridement affect oxidative stress parameters?
Authors
ŠÍN, Petr (203 Czech Republic, belonging to the institution), Alica HOKYNKOVÁ (703 Slovakia, guarantor, belonging to the institution), Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution), Hana PAULOVÁ (203 Czech Republic, belonging to the institution), Petr BABULA (203 Czech Republic, belonging to the institution), Andrea POKORNÁ (203 Czech Republic, belonging to the institution), Lucie NÁRTOVÁ (203 Czech Republic, belonging to the institution), Pavel COUFAL (203 Czech Republic, belonging to the institution) and Michal HENDRYCH (203 Czech Republic, belonging to the institution)
Edition
Ceska a slovenska neurologie a neurochirurgie, Prague, CZECH MEDICAL SOC, 2022, 1210-7859
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30212 Surgery
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 0.500
RIV identification code
RIV/00216224:14110/22:00129732
Organization unit
Faculty of Medicine
UT WoS
000910094000001
Keywords in English
pressure ulcer; pressure injury; debri-dement; Versajet hydrosurgery system; oxidative stress parameters
Tags
International impact, Reviewed
Změněno: 27/1/2023 14:17, Mgr. Tereza Miškechová
Abstract
V originále
Wound debridement is one of the crucial steps in wound bed preparation for surgical closure. Various debridement forms and tools can be employed. Aim: The prospective case series study aimed to compare the impact of two different types of debridement on oxidative stress parameters. Material and methods: This study included five patients with pressure ulcers of deep category various localisation. The wound was divided into halves. In one, the sharp debridement was performed, in the second Hydrosurgery Versajet (R) debridement was accomplished. Tissue, blood and urine samples were collected on days 0 and 7 after the surgery. Histopathological evaluation in tissue samples was performed. Oxidative stress parameters in plasma and urine were evaluated. Results: Diff erences in quality and quantity of granulation tissue between two types of debridement were found. An insignificant decrease of oxidative stress markers in blood plasma and urine 7 days after surgery were observed. Conclusions: Preliminary and pilot results suggest that the wound healing process is closely associated with markers of oxidative stress that are measurable in blood plasma and urine. These could be indicative of the healing process. A nonsignificant decrease was observed for all oxidative stress parameters on day 7 after the surgery. The pilot study will be followed by a detailed molecular bio logical analysis of tissue samples.
Links
| NU21-09-00541, research and development project |
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