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@article{2251353,
author = {Werff, ten Bosch Jutte van der and Hlaváčková, Eva and Derpoorter, Charlotte and Fischer, Ute and Saettini, Francesco and Ghosh, Sujal and Farah, Roula and Bogaert, Delfien and Wagener, Rabea and Loeffen, Jan and Bacon, Chris M and Bomken, Simon},
article_location = {Philadelphia},
article_number = {2},
doi = {http://dx.doi.org/10.1080/08880018.2022.2085830},
keywords = {Inborn errors of immunity; investigation; malignancy; pediatric; primary immunodeficiency},
language = {eng},
issn = {0888-0018},
journal = {Pediatric Hematology and Oncology},
title = {How to recognize inborn errors of immunity in a child presenting with a malignancy: guidelines for the pediatric hemato-oncologist},
url = {https://www.tandfonline.com/doi/full/10.1080/08880018.2022.2085830},
volume = {40},
year = {2023}
}
TY - JOUR
ID - 2251353
AU - Werff, ten Bosch Jutte van der - Hlaváčková, Eva - Derpoorter, Charlotte - Fischer, Ute - Saettini, Francesco - Ghosh, Sujal - Farah, Roula - Bogaert, Delfien - Wagener, Rabea - Loeffen, Jan - Bacon, Chris M - Bomken, Simon
PY - 2023
TI - How to recognize inborn errors of immunity in a child presenting with a malignancy: guidelines for the pediatric hemato-oncologist
JF - Pediatric Hematology and Oncology
VL - 40
IS - 2
SP - 131-146
EP - 131-146
PB - Taylor & Francis
SN - 08880018
KW - Inborn errors of immunity
KW - investigation
KW - malignancy
KW - pediatric
KW - primary immunodeficiency
UR - https://www.tandfonline.com/doi/full/10.1080/08880018.2022.2085830
N2 - Inborn errors of immunity (IEI) are a group of disorders caused by genetically determined defects in the immune system, leading to infections, autoimmunity, autoinflammation and an increased risk of malignancy. In some cases, a malignancy might be the first sign of an underlying IEI. As therapeutic strategies might be different in these patients, recognition of the underlying IEI by the pediatric hemato-oncologist is important. This article, written by a group of experts in pediatric immunology, hemato-oncology, pathology and genetics, aims to provide guidelines for pediatric hemato-oncologists on how to recognize a possible underlying IEI and what diagnostic tests can be performed, and gives some consideration to treatment possibilities.
ER -
WERFF, ten Bosch Jutte van der, Eva HLAVÁČKOVÁ, Charlotte DERPOORTER, Ute FISCHER, Francesco SAETTINI, Sujal GHOSH, Roula FARAH, Delfien BOGAERT, Rabea WAGENER, Jan LOEFFEN, Chris M BACON and Simon BOMKEN. How to recognize inborn errors of immunity in a child presenting with a malignancy: guidelines for the pediatric hemato-oncologist. \textit{Pediatric Hematology and Oncology}. Philadelphia: Taylor \&{} Francis, 2023, vol.~40, No~2, p.~131-146. ISSN~0888-0018. Available from: https://dx.doi.org/10.1080/08880018.2022.2085830.
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