| DE LUCA, Giuseppe, Matteo NARDIN, Magdy ALGOWHARY, Berat UGUZ, Dinaldo C OLIVEIRA, Vladimir GANYUKOV, Zan ZIMBAKOV, Miha CERCEK, Okkels Jensen LISETTE, Poay Huan LOH, Lucian CALMAC, Roura Ferrer GERARD, Alexandre QUADROS, Marek MILEWSKI, Scotto di Uccio FORTUNATO, von Birgelen CLEMENS, Francesco VERSACI, Ten Berg JURRIEN, Gianni CASELLA, Wong Sung Lung AARON, Petr KALA, Diez Gil Jose LUIS, Xavier CARRILLO, Maurits DIRKSEN, Victor M BECERRA-MUNOZ, Michael Kang-yin LEE, Arifa Juzar DAFSAH, de Moura Joaquim RODRIGO, Roberto PALADINO, Davor MILICIC, Periklis DAVLOUROS, Nikola BAKRACESKI, Filippo ZILIO, Luca DONAZZAN, Adriaan KRAAIJEVELD, Gennaro GALASSO, Arpad LUX, Lucia MARINUCCI, Vincenzo GUIDUCCI, Maurizio MENICHELLI, Alessandra SCOCCIA, Aylin Hatice YAMAC, Ugur Mert KADIR, Flores Rios XACOBE, Tomas KOVARNIK, Michal KIDAWA, Jose MOREU, Vincent FLAVIEN, Enrico FABRIS, Inigo Lozano MARTINEZ-LUENGAS, Marco BOCCALATTE, Bosa Ojeda FRANCISCO, Carlos ARELLANO-SERRANO, Gianluca CAIAZZO, Giuseppe CIRRINCIONE, Hsien-Li KAO, Sanchis Fores JUAN, Luigi VIGNALI, Helder PEREIRA, Stephane MANZO, Santiago ORDONEZ, Alev Arat OZKAN, Bruno SCHELLER, Heidi LEHTOLA, Rui TELES, Christos MANTIS, Ylitalo ANTTI, A. BRUM SILVEIRA JOAO, Rodrigo ZONI, Ivan BESSONOV, Stefano SAVONITTO, George KOCHIADAKIS, Dimitrios ALEXOPOULOS, Carlos E URIBE, John KANAKAKIS, Benjamin FAURIE, Gabriele GABRIELLI, Gutierrez Barrios ALEJANDRO, Juan Pablo BACHINI, Alex ROCHA, Frankie Chor-Cheung TAM, Alfredo RODRIGUEZ, Antonia Anna LUKITO, Veauthyelau SAINT-JOY, Gustavo PESSAH, Andrea TUCCILLO, Giuliana CORTESE, Guido PARODI, Mohamed Abed BOURAGHDA, Elvin KEDHI, Pablo LAMELAS, Harry SURYAPRANATA and Monica VERDOIA. Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry. RESPIRATORY RESEARCH. LONDON: BMC, 2022, vol. 23, No 1, p. 1-9. ISSN 1465-993X. Available from: https://dx.doi.org/10.1186/s12931-022-02128-0. |
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@article{2251536,
author = {De Luca, Giuseppe and Nardin, Matteo and Algowhary, Magdy and Uguz, Berat and Oliveira, Dinaldo C and Ganyukov, Vladimir and Zimbakov, Zan and Cercek, Miha and Lisette, Okkels Jensen and Loh, Poay Huan and Calmac, Lucian and Gerard, Roura Ferrer and Quadros, Alexandre and Milewski, Marek and Fortunato, Scotto di Uccio and Clemens, von Birgelen and Versaci, Francesco and Jurrien, Ten Berg and Casella, Gianni and Aaron, Wong Sung Lung and Kala, Petr and Luis, Diez Gil Jose and Carrillo, Xavier and Dirksen, Maurits and BecerraandMunoz, Victor M and Lee, Michael Kangandyin and Dafsah, Arifa Juzar and Rodrigo, de Moura Joaquim and Paladino, Roberto and Milicic, Davor and Davlouros, Periklis and Bakraceski, Nikola and Zilio, Filippo and Donazzan, Luca and Kraaijeveld, Adriaan and Galasso, Gennaro and Lux, Arpad and Marinucci, Lucia and Guiducci, Vincenzo and Menichelli, Maurizio and Scoccia, Alessandra and Yamac, Aylin Hatice and Kadir, Ugur Mert and Xacobe, Flores Rios and Kovarnik, Tomas and Kidawa, Michal and Moreu, Jose and Flavien, Vincent and Fabris, Enrico and MartinezandLuengas, Inigo Lozano and Boccalatte, Marco and Francisco, Bosa Ojeda and ArellanoandSerrano, Carlos and Caiazzo, Gianluca and Cirrincione, Giuseppe and Kao, HsienandLi and Juan, Sanchis Fores and Vignali, Luigi and Pereira, Helder and Manzo, Stephane and Ordonez, Santiago and Ozkan, Alev Arat and Scheller, Bruno and Lehtola, Heidi and Teles, Rui and Mantis, Christos and Antti, Ylitalo and Brum Silveira Joao, A. and Zoni, Rodrigo and Bessonov, Ivan and Savonitto, Stefano and Kochiadakis, George and Alexopoulos, Dimitrios and Uribe, Carlos E and Kanakakis, John and Faurie, Benjamin and Gabrielli, Gabriele and Alejandro, Gutierrez Barrios and Bachini, Juan Pablo and Rocha, Alex and Tam, Frankie ChorandCheung and Rodriguez, Alfredo and Lukito, Antonia Anna and SaintandJoy, Veauthyelau and Pessah, Gustavo and Tuccillo, Andrea and Cortese, Giuliana and Parodi, Guido and Bouraghda, Mohamed Abed and Kedhi, Elvin and Lamelas, Pablo and Suryapranata, Harry and Verdoia, Monica},
article_location = {LONDON},
article_number = {1},
doi = {http://dx.doi.org/10.1186/s12931-022-02128-0},
keywords = {STEMI; COPD; Mortality},
language = {eng},
issn = {1465-993X},
journal = {RESPIRATORY RESEARCH},
title = {Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry},
url = {https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-022-02128-0},
volume = {23},
year = {2022}
}
TY - JOUR
ID - 2251536
AU - De Luca, Giuseppe - Nardin, Matteo - Algowhary, Magdy - Uguz, Berat - Oliveira, Dinaldo C - Ganyukov, Vladimir - Zimbakov, Zan - Cercek, Miha - Lisette, Okkels Jensen - Loh, Poay Huan - Calmac, Lucian - Gerard, Roura Ferrer - Quadros, Alexandre - Milewski, Marek - Fortunato, Scotto di Uccio - Clemens, von Birgelen - Versaci, Francesco - Jurrien, Ten Berg - Casella, Gianni - Aaron, Wong Sung Lung - Kala, Petr - Luis, Diez Gil Jose - Carrillo, Xavier - Dirksen, Maurits - Becerra-Munoz, Victor M - Lee, Michael Kang-yin - Dafsah, Arifa Juzar - Rodrigo, de Moura Joaquim - Paladino, Roberto - Milicic, Davor - Davlouros, Periklis - Bakraceski, Nikola - Zilio, Filippo - Donazzan, Luca - Kraaijeveld, Adriaan - Galasso, Gennaro - Lux, Arpad - Marinucci, Lucia - Guiducci, Vincenzo - Menichelli, Maurizio - Scoccia, Alessandra - Yamac, Aylin Hatice - Kadir, Ugur Mert - Xacobe, Flores Rios - Kovarnik, Tomas - Kidawa, Michal - Moreu, Jose - Flavien, Vincent - Fabris, Enrico - Martinez-Luengas, Inigo Lozano - Boccalatte, Marco - Francisco, Bosa Ojeda - Arellano-Serrano, Carlos - Caiazzo, Gianluca - Cirrincione, Giuseppe - Kao, Hsien-Li - Juan, Sanchis Fores - Vignali, Luigi - Pereira, Helder - Manzo, Stephane - Ordonez, Santiago - Ozkan, Alev Arat - Scheller, Bruno - Lehtola, Heidi - Teles, Rui - Mantis, Christos - Antti, Ylitalo - Brum Silveira Joao, A. - Zoni, Rodrigo - Bessonov, Ivan - Savonitto, Stefano - Kochiadakis, George - Alexopoulos, Dimitrios - Uribe, Carlos E - Kanakakis, John - Faurie, Benjamin - Gabrielli, Gabriele - Alejandro, Gutierrez Barrios - Bachini, Juan Pablo - Rocha, Alex - Tam, Frankie Chor-Cheung - Rodriguez, Alfredo - Lukito, Antonia Anna - Saint-Joy, Veauthyelau - Pessah, Gustavo - Tuccillo, Andrea - Cortese, Giuliana - Parodi, Guido - Bouraghda, Mohamed Abed - Kedhi, Elvin - Lamelas, Pablo - Suryapranata, Harry - Verdoia, Monica
PY - 2022
TI - Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry
JF - RESPIRATORY RESEARCH
VL - 23
IS - 1
SP - 1-9
EP - 1-9
PB - BMC
SN - 1465993X
KW - STEMI
KW - COPD
KW - Mortality
UR - https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-022-02128-0
N2 - Background Chronic obstructive pulmonary disease (COPD) is projected to become the third cause of mortality worldwide. COPD shares several pathophysiological mechanisms with cardiovascular disease, especially atherosclerosis. However, no definite answers are available on the prognostic role of COPD in the setting of ST elevation myocardial infarction (STEMI), especially during COVID-19 pandemic, among patients undergoing primary angioplasty, that is therefore the aim of the current study. Methods In the ISACS-STEMI COVID-19 registry we included retrospectively patients with STEMI treated with primary percutaneous coronary intervention (PCI) between March and June of 2019 and 2020 from 109 high-volume primary PCI centers in 4 continents. Results A total of 15,686 patients were included in this analysis. Of them, 810 (5.2%) subjects had a COPD diagnosis. They were more often elderly and with a more pronounced cardiovascular risk profile. No preminent procedural dissimilarities were noticed except for a lower proportion of dual antiplatelet therapy at discharge among COPD patients (98.9% vs. 98.1%, P = 0.038). With regards to short-term fatal outcomes, both in-hospital and 30-days mortality occurred more frequently among COPD patients, similarly in pre-COVID-19 and COVID-19 era. However, after adjustment for main baseline differences, COPD did not result as independent predictor for in-hospital death (adjusted OR [95% CI] = 0.913[0.658-1.266], P = 0.585) nor for 30-days mortality (adjusted OR [95% CI] = 0.850 [0.620-1.164], P = 0.310). No significant differences were detected in terms of SARS-CoV-2 positivity between the two groups. Conclusion This is one of the largest studies investigating characteristics and outcome of COPD patients with STEMI undergoing primary angioplasty, especially during COVID pandemic. COPD was associated with significantly higher rates of in-hospital and 30-days mortality. However, this association disappeared after adjustment for baseline characteristics. Furthermore, COPD did not significantly affect SARS-CoV-2 positivity. Trial registration number: NCT 04412655 (2nd June 2020).
ER -
DE LUCA, Giuseppe, Matteo NARDIN, Magdy ALGOWHARY, Berat UGUZ, Dinaldo C OLIVEIRA, Vladimir GANYUKOV, Zan ZIMBAKOV, Miha CERCEK, Okkels Jensen LISETTE, Poay Huan LOH, Lucian CALMAC, Roura Ferrer GERARD, Alexandre QUADROS, Marek MILEWSKI, Scotto di Uccio FORTUNATO, von Birgelen CLEMENS, Francesco VERSACI, Ten Berg JURRIEN, Gianni CASELLA, Wong Sung Lung AARON, Petr KALA, Diez Gil Jose LUIS, Xavier CARRILLO, Maurits DIRKSEN, Victor M BECERRA-MUNOZ, Michael Kang-yin LEE, Arifa Juzar DAFSAH, de Moura Joaquim RODRIGO, Roberto PALADINO, Davor MILICIC, Periklis DAVLOUROS, Nikola BAKRACESKI, Filippo ZILIO, Luca DONAZZAN, Adriaan KRAAIJEVELD, Gennaro GALASSO, Arpad LUX, Lucia MARINUCCI, Vincenzo GUIDUCCI, Maurizio MENICHELLI, Alessandra SCOCCIA, Aylin Hatice YAMAC, Ugur Mert KADIR, Flores Rios XACOBE, Tomas KOVARNIK, Michal KIDAWA, Jose MOREU, Vincent FLAVIEN, Enrico FABRIS, Inigo Lozano MARTINEZ-LUENGAS, Marco BOCCALATTE, Bosa Ojeda FRANCISCO, Carlos ARELLANO-SERRANO, Gianluca CAIAZZO, Giuseppe CIRRINCIONE, Hsien-Li KAO, Sanchis Fores JUAN, Luigi VIGNALI, Helder PEREIRA, Stephane MANZO, Santiago ORDONEZ, Alev Arat OZKAN, Bruno SCHELLER, Heidi LEHTOLA, Rui TELES, Christos MANTIS, Ylitalo ANTTI, A. BRUM SILVEIRA JOAO, Rodrigo ZONI, Ivan BESSONOV, Stefano SAVONITTO, George KOCHIADAKIS, Dimitrios ALEXOPOULOS, Carlos E URIBE, John KANAKAKIS, Benjamin FAURIE, Gabriele GABRIELLI, Gutierrez Barrios ALEJANDRO, Juan Pablo BACHINI, Alex ROCHA, Frankie Chor-Cheung TAM, Alfredo RODRIGUEZ, Antonia Anna LUKITO, Veauthyelau SAINT-JOY, Gustavo PESSAH, Andrea TUCCILLO, Giuliana CORTESE, Guido PARODI, Mohamed Abed BOURAGHDA, Elvin KEDHI, Pablo LAMELAS, Harry SURYAPRANATA and Monica VERDOIA. Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry. \textit{RESPIRATORY RESEARCH}. LONDON: BMC, 2022, vol.~23, No~1, p.~1-9. ISSN~1465-993X. Available from: https://dx.doi.org/10.1186/s12931-022-02128-0.
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