| DE LUCA, Giuseppe, Magdy ALGOWHARY, Berat UGUZ, Dinaldo C OLIVEIRA, Vladimir GANYUKOV, Zan ZIMBAKOV, Miha CERCEK, Lisette Okkels JENSEN, Poay Huan LOH, Lucian CALMAC, Gerard Roura I FERRER, Alexandre QUADROS, Marek MILEWSKI, Di Uccio Fortunato SCOTTO, von Birgelen CLEMENS, Francesco VERSACI, Ten Berg JURRIEN, Gianni CASELLA, Aaron Wong Sung LUNG, Petr KALA, Jose Luis Diez GIL, Xavier CARRILLO, Maurits DIRKSEN, Victor M BECERRA-MUNOZ, Michael Kang-Yin LEE, Dafsah Arifa JUZAR, Rodrigo de Moura JOAQUIM, De Simone CIRO, Davor MILICIC, Periklis DAVLOUROS, Nikola BAKRACESKI, Filippo ZILIO, Luca DONAZZAN, Adriaan KRAAIJEVELD, Gennaro GALASSO, Lux ARPAD, Lucia MARINUCCI, Vincenzo GUIDUCCI, Maurizio MENICHELLI, Alessandra SCOCCIA, Aylin Hatice YAMAC, Kadir Ugur MERT, Xacobe Flores RIOS, Tomas KOVARNIK, Michal KIDAWA, Jose MOREU, Vincent FLAVIEN, Enrico FABRIS, Inigo Lozano MARTINEZ-LUENGAS, Marco BOCCALATTE, Francisco Bosa OJEDA, Carlos ARELLANO-SERRANO, Gianluca CAIAZZO, Giuseppe CIRRINCIONE, Hsien-Li KAO, Juan Sanchis FORES, Luigi VIGNALI, Helder PEREIRA, Stephane MANZO-SILBERMANN, Santiago ORDONEZ, Alev Arat OZKAN, Bruno SCHELLER, Heidi LEHTOLA, Rui TELES, Christos MANTIS, Ylitalo ANTTI, Joao Antonio Brum SILVEIRA, Ivan BESSONOV, Rodrigo ZONI, Stefano SAVONITTO, George KOCHIADAKIS, Dimitrios ALEXOPOULOS, Carlos E URIBE, John KANAKAKIS, Benjamin FAURIE, Gabriele GABRIELLI, Alejandro Gutierrez BARRIOS, Juan Pablo BACHINI, Alex ROCHA, Frankie Chor-Cheung TAM, Alfredo RODRIGUEZ, Antonia Anna LUKITO, Anne BELLEMAIN-APPAIX, Gustavo PESSAH, Giuliana CORTESE, Guido PARODI, Mohammed Abed BURGADHA, Elvin KEDHI, Pablo LAMELAS, Harry SURYAPRANATA, Matteo NARDIN and Monica VERDOIA. SARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion. ANGIOLOGY. THOUSAND OAKS: SAGE PUBLICATIONS INC, 2023, vol. 74, No 10, p. 987-996. ISSN 0003-3197. Available from: https://dx.doi.org/10.1177/00033197221129351. |
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@article{2251540,
author = {De Luca, Giuseppe and Algowhary, Magdy and Uguz, Berat and Oliveira, Dinaldo C and Ganyukov, Vladimir and Zimbakov, Zan and Cercek, Miha and Jensen, Lisette Okkels and Loh, Poay Huan and Calmac, Lucian and Ferrer, Gerard Roura I and Quadros, Alexandre and Milewski, Marek and Scotto, Di Uccio Fortunato and Clemens, von Birgelen and Versaci, Francesco and Jurrien, Ten Berg and Casella, Gianni and Lung, Aaron Wong Sung and Kala, Petr and Gil, Jose Luis Diez and Carrillo, Xavier and Dirksen, Maurits and BecerraandMunoz, Victor M and Lee, Michael KangandYin and Juzar, Dafsah Arifa and Joaquim, Rodrigo de Moura and Ciro, De Simone and Milicic, Davor and Davlouros, Periklis and Bakraceski, Nikola and Zilio, Filippo and Donazzan, Luca and Kraaijeveld, Adriaan and Galasso, Gennaro and Arpad, Lux and Marinucci, Lucia and Guiducci, Vincenzo and Menichelli, Maurizio and Scoccia, Alessandra and Yamac, Aylin Hatice and Mert, Kadir Ugur and Rios, Xacobe Flores and Kovarnik, Tomas and Kidawa, Michal and Moreu, Jose and Flavien, Vincent and Fabris, Enrico and MartinezandLuengas, Inigo Lozano and Boccalatte, Marco and Ojeda, Francisco Bosa and ArellanoandSerrano, Carlos and Caiazzo, Gianluca and Cirrincione, Giuseppe and Kao, HsienandLi and Fores, Juan Sanchis and Vignali, Luigi and Pereira, Helder and ManzoandSilbermann, Stephane and Ordonez, Santiago and Ozkan, Alev Arat and Scheller, Bruno and Lehtola, Heidi and Teles, Rui and Mantis, Christos and Antti, Ylitalo and Silveira, Joao Antonio Brum and Bessonov, Ivan and Zoni, Rodrigo and Savonitto, Stefano and Kochiadakis, George and Alexopoulos, Dimitrios and Uribe, Carlos E and Kanakakis, John and Faurie, Benjamin and Gabrielli, Gabriele and Barrios, Alejandro Gutierrez and Bachini, Juan Pablo and Rocha, Alex and Tam, Frankie ChorandCheung and Rodriguez, Alfredo and Lukito, Antonia Anna and BellemainandAppaix, Anne and Pessah, Gustavo and Cortese, Giuliana and Parodi, Guido and Burgadha, Mohammed Abed and Kedhi, Elvin and Lamelas, Pablo and Suryapranata, Harry and Nardin, Matteo and Verdoia, Monica},
article_location = {THOUSAND OAKS},
article_number = {10},
doi = {http://dx.doi.org/10.1177/00033197221129351},
keywords = {thrombosis; STEMI; outcome},
language = {eng},
issn = {0003-3197},
journal = {ANGIOLOGY},
title = {SARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion},
url = {https://journals.sagepub.com/doi/10.1177/00033197221129351},
volume = {74},
year = {2023}
}
TY - JOUR
ID - 2251540
AU - De Luca, Giuseppe - Algowhary, Magdy - Uguz, Berat - Oliveira, Dinaldo C - Ganyukov, Vladimir - Zimbakov, Zan - Cercek, Miha - Jensen, Lisette Okkels - Loh, Poay Huan - Calmac, Lucian - Ferrer, Gerard Roura I - Quadros, Alexandre - Milewski, Marek - Scotto, Di Uccio Fortunato - Clemens, von Birgelen - Versaci, Francesco - Jurrien, Ten Berg - Casella, Gianni - Lung, Aaron Wong Sung - Kala, Petr - Gil, Jose Luis Diez - Carrillo, Xavier - Dirksen, Maurits - Becerra-Munoz, Victor M - Lee, Michael Kang-Yin - Juzar, Dafsah Arifa - Joaquim, Rodrigo de Moura - Ciro, De Simone - Milicic, Davor - Davlouros, Periklis - Bakraceski, Nikola - Zilio, Filippo - Donazzan, Luca - Kraaijeveld, Adriaan - Galasso, Gennaro - Arpad, Lux - Marinucci, Lucia - Guiducci, Vincenzo - Menichelli, Maurizio - Scoccia, Alessandra - Yamac, Aylin Hatice - Mert, Kadir Ugur - Rios, Xacobe Flores - Kovarnik, Tomas - Kidawa, Michal - Moreu, Jose - Flavien, Vincent - Fabris, Enrico - Martinez-Luengas, Inigo Lozano - Boccalatte, Marco - Ojeda, Francisco Bosa - Arellano-Serrano, Carlos - Caiazzo, Gianluca - Cirrincione, Giuseppe - Kao, Hsien-Li - Fores, Juan Sanchis - Vignali, Luigi - Pereira, Helder - Manzo-Silbermann, Stephane - Ordonez, Santiago - Ozkan, Alev Arat - Scheller, Bruno - Lehtola, Heidi - Teles, Rui - Mantis, Christos - Antti, Ylitalo - Silveira, Joao Antonio Brum - Bessonov, Ivan - Zoni, Rodrigo - Savonitto, Stefano - Kochiadakis, George - Alexopoulos, Dimitrios - Uribe, Carlos E - Kanakakis, John - Faurie, Benjamin - Gabrielli, Gabriele - Barrios, Alejandro Gutierrez - Bachini, Juan Pablo - Rocha, Alex - Tam, Frankie Chor-Cheung - Rodriguez, Alfredo - Lukito, Antonia Anna - Bellemain-Appaix, Anne - Pessah, Gustavo - Cortese, Giuliana - Parodi, Guido - Burgadha, Mohammed Abed - Kedhi, Elvin - Lamelas, Pablo - Suryapranata, Harry - Nardin, Matteo - Verdoia, Monica
PY - 2023
TI - SARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion
JF - ANGIOLOGY
VL - 74
IS - 10
SP - 987-996
EP - 987-996
PB - SAGE PUBLICATIONS INC
SN - 00033197
KW - thrombosis
KW - STEMI
KW - outcome
UR - https://journals.sagepub.com/doi/10.1177/00033197221129351
N2 - SARS-Cov-2 has been suggested to promote thrombotic complications and higher mortality. The aim of the present study was to evaluate the impact of SARS-CoV-2 positivity on in-hospital outcome and 30-day mortality in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) enrolled in the International Survey on Acute Coronary Syndromes ST-segment elevation Myocardial Infarction (ISACS-STEMI COVID-19 registry. The 109 SARS-CoV-2 positive patients were compared with 2005 SARS-CoV-2 negative patients. Positive patients were older (P = .002), less often active smokers (P = .002), and hypercholesterolemic (P = .006), they presented more often later than 12 h (P = .037), more often to the hub and were more often in cardiogenic shock (P = .02), or requiring rescue percutaneous coronary intervention after failed thrombolysis (P < .0001). Lower postprocedural Thrombolysis in Myocardial Infarction 3 flow (P = .029) and more thrombectomy (P = .046) were observed. SARS-CoV-2 was associated with a significantly higher in-hospital mortality (25.7 vs 7%, adjusted Odds Ratio (OR) [95% Confidence Interval] = 3.2 [1.71-5.99], P < .001) in-hospital definite in-stent thrombosis (6.4 vs 1.1%, adjusted Odds Ratio [95% CI] = 6.26 [2.41-16.25], P < .001) and 30-day mortality (34.4 vs 8.5%, adjusted Hazard Ratio [95% CI] = 2.16 [1.45-3.23], P < .001), confirming that SARS-CoV-2 positivity is associated with impaired reperfusion, with negative prognostic consequences.
ER -
DE LUCA, Giuseppe, Magdy ALGOWHARY, Berat UGUZ, Dinaldo C OLIVEIRA, Vladimir GANYUKOV, Zan ZIMBAKOV, Miha CERCEK, Lisette Okkels JENSEN, Poay Huan LOH, Lucian CALMAC, Gerard Roura I FERRER, Alexandre QUADROS, Marek MILEWSKI, Di Uccio Fortunato SCOTTO, von Birgelen CLEMENS, Francesco VERSACI, Ten Berg JURRIEN, Gianni CASELLA, Aaron Wong Sung LUNG, Petr KALA, Jose Luis Diez GIL, Xavier CARRILLO, Maurits DIRKSEN, Victor M BECERRA-MUNOZ, Michael Kang-Yin LEE, Dafsah Arifa JUZAR, Rodrigo de Moura JOAQUIM, De Simone CIRO, Davor MILICIC, Periklis DAVLOUROS, Nikola BAKRACESKI, Filippo ZILIO, Luca DONAZZAN, Adriaan KRAAIJEVELD, Gennaro GALASSO, Lux ARPAD, Lucia MARINUCCI, Vincenzo GUIDUCCI, Maurizio MENICHELLI, Alessandra SCOCCIA, Aylin Hatice YAMAC, Kadir Ugur MERT, Xacobe Flores RIOS, Tomas KOVARNIK, Michal KIDAWA, Jose MOREU, Vincent FLAVIEN, Enrico FABRIS, Inigo Lozano MARTINEZ-LUENGAS, Marco BOCCALATTE, Francisco Bosa OJEDA, Carlos ARELLANO-SERRANO, Gianluca CAIAZZO, Giuseppe CIRRINCIONE, Hsien-Li KAO, Juan Sanchis FORES, Luigi VIGNALI, Helder PEREIRA, Stephane MANZO-SILBERMANN, Santiago ORDONEZ, Alev Arat OZKAN, Bruno SCHELLER, Heidi LEHTOLA, Rui TELES, Christos MANTIS, Ylitalo ANTTI, Joao Antonio Brum SILVEIRA, Ivan BESSONOV, Rodrigo ZONI, Stefano SAVONITTO, George KOCHIADAKIS, Dimitrios ALEXOPOULOS, Carlos E URIBE, John KANAKAKIS, Benjamin FAURIE, Gabriele GABRIELLI, Alejandro Gutierrez BARRIOS, Juan Pablo BACHINI, Alex ROCHA, Frankie Chor-Cheung TAM, Alfredo RODRIGUEZ, Antonia Anna LUKITO, Anne BELLEMAIN-APPAIX, Gustavo PESSAH, Giuliana CORTESE, Guido PARODI, Mohammed Abed BURGADHA, Elvin KEDHI, Pablo LAMELAS, Harry SURYAPRANATA, Matteo NARDIN and Monica VERDOIA. SARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion. \textit{ANGIOLOGY}. THOUSAND OAKS: SAGE PUBLICATIONS INC, 2023, vol.~74, No~10, p.~987-996. ISSN~0003-3197. Available from: https://dx.doi.org/10.1177/00033197221129351.
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