BACKGROUD: 3Diamond represents a software product that enables efficient management of the data needed to control 3D printing tasks in a hospital or clinical settings. METHODS: The softwarethat de-facto resembles a product life- -cycle (PLM) system, has been designed by a common effort of biomedical engineers, software developers, clinical data managers, and clinical experts. RESULTS: The PLM software 3DIAMOND has been powered by Clade-IS, which is an EDC (Electronic Data Capture) system, commonly used in clinical research for the facilitation of data management in clinical studies and real-world data projects. DISCUSSION: Due to cyber threats and data privacy regulations, 3D printing tasks need to be handled through valid information systems rather than WhatsApp and USB flash drives.