Detailed Information on Publication Record
2022
Pregnancy and Spontaneous Coronary Artery Dissection: Lessons From Survivors and Nonsurvivors
CHAN, Nathan, Diluka PREMAWARDHANA, Abtehale AL-HUSSAINI, Alice WOOD, Vasiliki BOUNTZIOUKA et. al.Basic information
Original name
Pregnancy and Spontaneous Coronary Artery Dissection: Lessons From Survivors and Nonsurvivors
Authors
CHAN, Nathan, Diluka PREMAWARDHANA, Abtehale AL-HUSSAINI, Alice WOOD, Vasiliki BOUNTZIOUKA, Deevia KOTECHA, Eva SWAHN, Henning PALMEFORS, Christos PAGONIS, Sofia Sederholm LAWESSON, Jacek KADZIELA, Marcos GARCIA-GUIMARAES, Fernando ALFONSO, Javier ESCANED, Fernando MACAYA, Melisa SANTAS, Enrico CERRATO, Angela H E M MAAS, Ota HLINOMAZ (203 Czech Republic, belonging to the institution), Nigussie BOGALE, Bernardo CORTESE, Mavis CHENG, Aidan BOLGER, Shazia T HUSSAIN, Nilesh J SAMANI, Marian KNIGHT, Matthew CAULDWELL and David ADLAM (guarantor)
Edition
Circulation, Philadelphia, Lippincott Williams Wilkins, 2022, 0009-7322
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30201 Cardiac and Cardiovascular systems
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 37.800
RIV identification code
RIV/00216224:14110/22:00128486
Organization unit
Faculty of Medicine
UT WoS
000823965200011
Keywords in English
coronary vessels; maternal death; myocardial infarction; pregnancy
Tags
International impact, Reviewed
Změněno: 1/2/2023 14:13, Mgr. Tereza Miškechová
Abstract
V originále
Spontaneous coronary artery dissection (SCAD) is an important cause of myocardial infarction associated with pregnancy (P-SCAD). It is also an understudied cause of maternal death. The present study aimed to report clinical presentation and management of P-SCAD in survivors and non-survivors and to investigate the outcome of pregnancies in women with previous SCAD. Patients were recruited from European SCAD registries with SCAD events from 1984 to 2021. All registries were approved by national or institutional ethical review boards. All patients gave written informed consent. The P-SCAD case series consisted of 82 patients (median age, 36 years [interquartile range, 5]; 94% never/former smokers, 85% White, 15% with hypertension, 5% with diabetes, 13% with dyslipidemia, 2% with previous stroke, 22% with family history of coronary artery disease,16% with extracoronary arteriopathies, and 48% with incomplete screening). Patients were alive at the time of enrollment and presented with SCAD confirmed on invasive angiography occurring during pregnancy or within 12 months of delivery, miscarriage, or termination. The pregnancy after previous SCAD series consisted of 37 pregnancies in 28 patients with angiographically confirmed SCAD who reported a subsequent pregnancy, whether ending in live birth, miscarriage, or termination. Data on 13 patients who did not survive P-SCAD were collected from the MBRRACE-UK audit of maternal deaths. The timing of SCAD in the P-SCAD case series is shown in the Figure. Few (n = 5) SCAD events occurred during pregnancy, with the peak time of vulnerability the first month after delivery. One patient had P-SCAD 4 months after miscarriage during her first trimester. Another had P-SCAD 3 weeks after medical termination.