FIALOVÁ, Dana, Eva DROZDOVÁ, Eva CHOCHOLOVÁ, Kristýna BRZOBOHATÁ, Filip PARDY, Anna ŠENOVSKÁ, Hana SVOBODOVÁ, Kateřina NOVOTNÁ, Boris TICHÝ, Marek PEŠKA, Antonín ZŮBEK, Michael DOUBEK and Šárka POSPÍŠILOVÁ. Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains. Folia Mendeliana : supplementum ad Acta Musei Moraviae. Moravian Museum Brno, 2022, vol. 58, No 1, p. 29-36. ISSN 0085-0748.
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Basic information
Original name Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains
Authors FIALOVÁ, Dana (203 Czech Republic, guarantor, belonging to the institution), Eva DROZDOVÁ (203 Czech Republic, belonging to the institution), Eva CHOCHOLOVÁ (203 Czech Republic, belonging to the institution), Kristýna BRZOBOHATÁ (203 Czech Republic, belonging to the institution), Filip PARDY (203 Czech Republic, belonging to the institution), Anna ŠENOVSKÁ (203 Czech Republic, belonging to the institution), Hana SVOBODOVÁ (203 Czech Republic, belonging to the institution), Kateřina NOVOTNÁ (203 Czech Republic, belonging to the institution), Boris TICHÝ (203 Czech Republic, belonging to the institution), Marek PEŠKA, Antonín ZŮBEK, Michael DOUBEK (203 Czech Republic, belonging to the institution) and Šárka POSPÍŠILOVÁ (203 Czech Republic, belonging to the institution).
Edition Folia Mendeliana : supplementum ad Acta Musei Moraviae, Moravian Museum Brno, 2022, 0085-0748.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10608 Biochemistry and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14310/22:00128534
Organization unit Faculty of Science
Keywords in English Gregor Johann Mendel; mitogenome; palaeogenomics
Tags International impact
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 16/2/2023 11:52.
Abstract
Skeletal remains of five members of the Order of St. Augustine were found in the tomb at the Central Cemetery in Brno during an archaeological excavation in 2021. The aim was to identify Gregor Johann Mendel. Archaeological, anthropological, and genetic approaches were used for this purpose. However, the most reliable method to distinguish his skeletal remains was genetic identification. Specifically, the whole mitochondrial DNA (mitogenome) was read by next-generation sequencing (NGS). The mitogenomes of all five men and twenty DNA samples from Mendel’s personal belongings (e.g., hair from his books and swabs) were compared. A match was found with one hair. The positive identification paved the way for proceeding with the project and reading his entire genome.
Links
LM2015085, research and development projectName: CERIT Scientific Cloud (Acronym: CERIT-SC)
Investor: Ministry of Education, Youth and Sports of the CR, CERIT Scientific Cloud
LM2018132, research and development projectName: Národní centrum lékařské genomiky (Acronym: NCLG)
Investor: Ministry of Education, Youth and Sports of the CR, National Center for Medical Genomics
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