J 2022

Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains

FIALOVÁ, Dana, Eva DROZDOVÁ, Eva CHOCHOLOVÁ, Kristýna BRZOBOHATÁ, Filip PARDY et. al.

Basic information

Original name

Multidisciplinary approach to identification of Gregor Johann Mendel's skeletal remains

Authors

FIALOVÁ, Dana (203 Czech Republic, guarantor, belonging to the institution), Eva DROZDOVÁ (203 Czech Republic, belonging to the institution), Eva CHOCHOLOVÁ (203 Czech Republic, belonging to the institution), Kristýna BRZOBOHATÁ (203 Czech Republic, belonging to the institution), Filip PARDY (203 Czech Republic, belonging to the institution), Anna ŠENOVSKÁ (203 Czech Republic, belonging to the institution), Hana SVOBODOVÁ (203 Czech Republic, belonging to the institution), Kateřina NOVOTNÁ (203 Czech Republic, belonging to the institution), Boris TICHÝ (203 Czech Republic, belonging to the institution), Marek PEŠKA, Antonín ZŮBEK, Michael DOUBEK (203 Czech Republic, belonging to the institution) and Šárka POSPÍŠILOVÁ (203 Czech Republic, belonging to the institution)

Edition

Folia Mendeliana : supplementum ad Acta Musei Moraviae, Moravian Museum Brno, 2022, 0085-0748

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10608 Biochemistry and molecular biology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14310/22:00128534

Organization unit

Faculty of Science

Keywords in English

Gregor Johann Mendel; mitogenome; palaeogenomics

Tags

International impact
Změněno: 16/2/2023 11:52, Mgr. Marie Šípková, DiS.

Abstract

V originále

Skeletal remains of five members of the Order of St. Augustine were found in the tomb at the Central Cemetery in Brno during an archaeological excavation in 2021. The aim was to identify Gregor Johann Mendel. Archaeological, anthropological, and genetic approaches were used for this purpose. However, the most reliable method to distinguish his skeletal remains was genetic identification. Specifically, the whole mitochondrial DNA (mitogenome) was read by next-generation sequencing (NGS). The mitogenomes of all five men and twenty DNA samples from Mendel’s personal belongings (e.g., hair from his books and swabs) were compared. A match was found with one hair. The positive identification paved the way for proceeding with the project and reading his entire genome.

Links

LM2015085, research and development project
Name: CERIT Scientific Cloud (Acronym: CERIT-SC)
Investor: Ministry of Education, Youth and Sports of the CR, CERIT Scientific Cloud
LM2018132, research and development project
Name: Národní centrum lékařské genomiky (Acronym: NCLG)
Investor: Ministry of Education, Youth and Sports of the CR, National Center for Medical Genomics