P 2022

Substituted propanamides as inhibitors of nucleases

PARUCH, Kamil, Benoit Jean-Pierre CARBAIN, Štěpán HAVEL, Vít VŠIANSKÝ, Fedor NIKULENKOV et. al.

Basic information

Original name

Substituted propanamides as inhibitors of nucleases

Authors

PARUCH, Kamil (203 Czech Republic, belonging to the institution), Benoit Jean-Pierre CARBAIN (250 France, belonging to the institution), Štěpán HAVEL (203 Czech Republic, belonging to the institution), Vít VŠIANSKÝ (203 Czech Republic, belonging to the institution), Fedor NIKULENKOV (203 Czech Republic, belonging to the institution) and Lumír KREJČÍ (203 Czech Republic, belonging to the institution)

Edition

Number: AU2019256672, Publisher: IP Australia, Place of publication: Woden ACT, Owner's name: Masarykova univerzita, 2022

Other information

Language

English

Type of outcome

Patent

Field of Study

10401 Organic chemistry

Country of publisher

Australia

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14310/22:00134802

Organization unit

Faculty of Science

Keywords in English

DNA; propanamide; nuclease

Tags

Tags

International impact
Změněno: 6/8/2024 10:40, Mgr. Marie Šípková, DiS.

Abstract

V originále

Compounds represented by the structural formula (1) where R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

Links

EF16_025/0007381, research and development project
Name: Preklinická progrese nových organických sloučenin s cílenou biologickou aktivitou
LM2018130, research and development project
Name: Národní infrastruktura chemické biologie (Acronym: CZ-­OPENSCREEN)
Investor: Ministry of Education, Youth and Sports of the CR