| KUBÍČEK, Luboš, Radek VITASEK, David SCHWARZ, Robert STAFFA, Petr STRAKOS and Stanislav POLZER. Biomechanical Rupture Risk Assessment in Management of Patients with Abdominal Aortic Aneurysm in COVID-19 Pandemic. Diagnostics. Basel: MDPI, 2023, vol. 13, No 1, p. 1-12. ISSN 2075-4418. Available from: https://dx.doi.org/10.3390/diagnostics13010132. |
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@article{2258298,
author = {Kubíček, Luboš and Vitasek, Radek and Schwarz, David and Staffa, Robert and Strakos, Petr and Polzer, Stanislav},
article_location = {Basel},
article_number = {1},
doi = {http://dx.doi.org/10.3390/diagnostics13010132},
keywords = {abdominal aortic aneurysm; biomechanics; rupture risk; predictability; COVID-19},
language = {eng},
issn = {2075-4418},
journal = {Diagnostics},
title = {Biomechanical Rupture Risk Assessment in Management of Patients with Abdominal Aortic Aneurysm in COVID-19 Pandemic},
url = {https://www.mdpi.com/2075-4418/13/1/132},
volume = {13},
year = {2023}
}
TY - JOUR
ID - 2258298
AU - Kubíček, Luboš - Vitasek, Radek - Schwarz, David - Staffa, Robert - Strakos, Petr - Polzer, Stanislav
PY - 2023
TI - Biomechanical Rupture Risk Assessment in Management of Patients with Abdominal Aortic Aneurysm in COVID-19 Pandemic
JF - Diagnostics
VL - 13
IS - 1
SP - 1-12
EP - 1-12
PB - MDPI
SN - 20754418
KW - abdominal aortic aneurysm
KW - biomechanics
KW - rupture risk
KW - predictability
KW - COVID-19
UR - https://www.mdpi.com/2075-4418/13/1/132
N2 - Background: The acute phase of the COVID-19 pandemic requires a redefinition of healthcare system to increase the number of available intensive care units for COVID-19 patients. This leads to the postponement of elective surgeries including the treatment of abdominal aortic aneurysm (AAA). The probabilistic rupture risk index (PRRI) recently showed its advantage over the diameter criterion in AAA rupture risk assessment. Its major improvement is in increased specificity and yet has the same sensitivity as the maximal diameter criterion. The objective of this study was to test the clinical applicability of the PRRI method in a quasi-prospective patient cohort study. Methods: Nineteen patients (fourteen males, five females) with intact AAA who were postponed due to COVID-19 pandemic were included in this study. The PRRI was calculated at the baseline via finite element method models. If a case was diagnosed as high risk (PRRI > 3%), the patient was offered priority in AAA intervention. Cases were followed until 10 September 2021 and a number of false positive and false negative cases were recorded. Results: Each case was assessed within 3 days. Priority in intervention was offered to two patients with high PRRI. There were four false positive cases and no false negative cases classified by PRRI. In three cases, the follow-up was very short to reach any conclusion. Conclusions: Integrating PRRI into clinical workflow is possible. Longitudinal validation of PRRI did not fail and may significantly decrease the false positive rate in AAA treatment.
ER -
KUBÍČEK, Luboš, Radek VITASEK, David SCHWARZ, Robert STAFFA, Petr STRAKOS and Stanislav POLZER. Biomechanical Rupture Risk Assessment in Management of Patients with Abdominal Aortic Aneurysm in COVID-19 Pandemic. \textit{Diagnostics}. Basel: MDPI, 2023, vol.~13, No~1, p.~1-12. ISSN~2075-4418. Available from: https://dx.doi.org/10.3390/diagnostics13010132.
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