Other formats:
BibTeX
LaTeX
RIS
@article{2264628,
author = {Polechova, Jitka and Johnson, Kory D and Payne, Pavel and Crozier, Alex and Beiglboeck, Mathias and Plevka, Pavel and Schernhammer, Eva},
article_location = {New York},
article_number = {MAY},
doi = {http://dx.doi.org/10.1016/j.jclinepi.2022.01.002},
keywords = {COVID-19; SARS-CoV-2; Lateral flow device; Public health; Repeat testing; Large-scale testing},
language = {eng},
issn = {0895-4356},
journal = {Journal of clinical epidemiology},
title = {SARS-CoV-2 rapid antigen tests provide benefits for epidemic control - observations from Austrian schools},
url = {https://www.sciencedirect.com/science/article/pii/S0895435622000087?via%3Dihub},
volume = {145},
year = {2022}
}
TY - JOUR
ID - 2264628
AU - Polechova, Jitka - Johnson, Kory D - Payne, Pavel - Crozier, Alex - Beiglboeck, Mathias - Plevka, Pavel - Schernhammer, Eva
PY - 2022
TI - SARS-CoV-2 rapid antigen tests provide benefits for epidemic control - observations from Austrian schools
JF - Journal of clinical epidemiology
VL - 145
IS - MAY
SP - 14-19
EP - 14-19
PB - Elsevier
SN - 08954356
KW - COVID-19
KW - SARS-CoV-2
KW - Lateral flow device
KW - Public health
KW - Repeat testing
KW - Large-scale testing
UR - https://www.sciencedirect.com/science/article/pii/S0895435622000087?via%3Dihub
N2 - Objective: This paper motivates and justifies the use of antigen tests for epidemic control as distinct from a diagnostic test. Study Design and Setting: We discuss the relative advantages of antigen and PCR tests, summarizing evidence from both the literature as well as Austrian schools, which conducted frequent, mass rapid antigen testing during the spring of 2021. While our report on testing predates Delta, we have updated the review with recent data on viral loads in breakthrough infections and more information about testing efficacy, especially in children. Results: Rapid antigen tests detect proteins at the surface of virus particles, identifying the disease during its infectious phase. In contrast, PCR tests detect viral genomes: they can thus diagnose COVID-19 before the infectious phase but also react to remnants of the virus genome, even weeks after live virus ceases to be detectable in the respiratory tract. Furthermore, the logistics for administering the tests are different. Large-scale rapid antigen testing in Austrian schools showed low false-positive rates along with an approximately 10% lower effective reproduction number in the tested cohort. Conclusion: Using antigen tests at least 2-3 times per week could become a powerful tool to suppress the COVID-19 pandemic. (c) 2022 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
ER -
POLECHOVA, Jitka, Kory D JOHNSON, Pavel PAYNE, Alex CROZIER, Mathias BEIGLBOECK, Pavel PLEVKA and Eva SCHERNHAMMER. SARS-CoV-2 rapid antigen tests provide benefits for epidemic control - observations from Austrian schools. \textit{Journal of clinical epidemiology}. New York: Elsevier, 2022, vol.~145, MAY, p.~14-19. ISSN~0895-4356. Available from: https://dx.doi.org/10.1016/j.jclinepi.2022.01.002.
|
