SVATOŇ, Roman, Vladimír PROCHÁZKA, Markéta HANSLIANOVÁ and Zdeněk KALA. Influence of bacteriobilia on postoperative complications in patients with periampullary tumors. Asian Journal of Surgery. SINGAPORE: ELSEVIER SINGAPORE PTE LTD, 2023, vol. 46, No 3, p. 1193-1198. ISSN 1015-9584. Available from: https://dx.doi.org/10.1016/j.asjsur.2022.08.072.
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Basic information
Original name Influence of bacteriobilia on postoperative complications in patients with periampullary tumors
Authors SVATOŇ, Roman (703 Slovakia, guarantor, belonging to the institution), Vladimír PROCHÁZKA (203 Czech Republic, belonging to the institution), Markéta HANSLIANOVÁ (203 Czech Republic, belonging to the institution) and Zdeněk KALA (203 Czech Republic, belonging to the institution).
Edition Asian Journal of Surgery, SINGAPORE, ELSEVIER SINGAPORE PTE LTD, 2023, 1015-9584.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30212 Surgery
Country of publisher Singapore
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.500 in 2022
RIV identification code RIV/00216224:14110/23:00130476
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.asjsur.2022.08.072
UT WoS 000953399000001
Keywords in English Bacteriobilia; Complications; Periampullary tumor
Tags 14110223, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 15/3/2024 10:11.
Abstract
Background Periampullary tumours (PAT) may cause obstruction of distal choledochus. The bile stasis is a risk factor for microbial colonisation of bile (bacteriobilia), cholangitis, hepatic insufficiency and coagulopathy. PAT obstruction can be managed surgically or non-operatively - by inserting a biliary drain or stent (BDS). Although BDS allows for adequate bile drainage, liver function restitution and coagulopathy, increased bacteriobilia has been reported and this is associated with an increased incidence of postoperative complications. Methods A monocentric, prospective, comparative study including 100 patients operated with PAT. The effects of bacteriobilia and the presence of a drain in the biliary tract on the development of postoperative complications were evaluated. Results Positive microbial findings in bile were found in 67% of patients. It was 98% in the biliary drain group vs. 36% in non-drained patients (p = 0.0001). In 68% 2 or more different bacterial strains were simultaneously present (p = 0.0001). Patients with a positive microbial finding in bile had more frequent incidence of infectious complications 40.2% (27) vs. 9.1% (3); p = 0.0011. The most frequent infectious complication was wound infection 29.8% (20) vs. 3.03% (1); p = 0.0014. Similarly, a higher incidence of postoperative infectious complications occurred in patients with BDS - 36% (18) vs. 24% (12); p = 0.2752. Conclusion The presence of a drain or stent in the biliary tract significantly increases the microbial colonisation of bile. It is associated with a significant increase in infectious complications, especially infections in the wound.
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