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@inproceedings{2268703,
author = {Trnková, Libuše and Třísková, Iveta and Farka, Zdeněk},
address = {Ústí nad Labem},
booktitle = {41. Moderní elektrochemické metody : Sborník přednášek},
editor = {Navrátil, Tomáš; Fojta, Miroslav; Schwarzová},
keywords = {Insulin; Tyrosine; Screen-printed graphite electrode; Pencil graphite electrodes; Voltammetry; Circular dichroism; Denaturation; BeStSel},
howpublished = {tištěná verze "print"},
language = {eng},
location = {Ústí nad Labem},
isbn = {978-80-905221-9-0},
pages = {200-203},
publisher = {Best Servis},
title = {Electrochemical Analysis of Insulin on Graphite Electrodes},
url = {https://www.bestservis.eu/images/file/Sbornik_metody22.pdf},
year = {2022}
}
TY - JOUR
ID - 2268703
AU - Trnková, Libuše - Třísková, Iveta - Farka, Zdeněk
PY - 2022
TI - Electrochemical Analysis of Insulin on Graphite Electrodes
PB - Best Servis
CY - Ústí nad Labem
SN - 9788090522190
KW - Insulin
KW - Tyrosine
KW - Screen-printed graphite electrode
KW - Pencil graphite electrodes
KW - Voltammetry
KW - Circular dichroism
KW - Denaturation
KW - BeStSel
UR - https://www.bestservis.eu/images/file/Sbornik_metody22.pdf
N2 - Electrochemical study of insulin on non-modified and nanoparticle-modified graphite electrodes was performed. The insulin oxidation signal, for which tyrosine is responsible, has been investigated not only in terms of insulin forms (native, denatured, dimeric, monomeric) and adjustable solution parameters (pH, concentration, ionic strength, and buffer) but also in terms of the modification of electrode surface. It was found that all the above-mentioned parameters have effect on insulin oxidation, but the greatest changes in voltammetric signals were caused by the nano-modification of electrode surfaces and the structure of insulin. The information about the secondary structure of insulin in solutions was obtained by measuring circular dichroism spectra and their subsequent evaluation using a novel method for secondary structure determination of proteins BeStSel (Beta Structure Selection).
ER -
TRNKOVÁ, Libuše, Iveta TŘÍSKOVÁ and Zdeněk FARKA. Electrochemical Analysis of Insulin on Graphite Electrodes. In Navrátil, Tomáš; Fojta, Miroslav; Schwarzová. \textit{41. Moderní elektrochemické metody : Sborník přednášek}. Ústí nad Labem: Best Servis, 2022, p.~200-203. ISBN~978-80-905221-9-0.
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