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@article{2270557, author = {Balazova, Ludmila and Wolaschka, Tomáš and Rohaľová, Simona and Daneu, Nina and Stahorsky, Martin and Salayova, Aneta and Tkacikova, Ludmila and Eftimova, Jarmila}, article_location = {BASEL}, article_number = {2}, doi = {http://dx.doi.org/10.3390/life13020573}, keywords = {nanoparticles; silver; Agrimonia eupatoria; in situ gel}, language = {eng}, issn = {2075-1729}, journal = {LIFE-BASEL}, title = {In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity}, url = {https://mdpi-res.com/d_attachment/life/life-13-00573/article_deploy/life-13-00573-v2.pdf?version=1676886955}, volume = {13}, year = {2023} }
TY - JOUR ID - 2270557 AU - Balazova, Ludmila - Wolaschka, Tomáš - Rohaľová, Simona - Daneu, Nina - Stahorsky, Martin - Salayova, Aneta - Tkacikova, Ludmila - Eftimova, Jarmila PY - 2023 TI - In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity JF - LIFE-BASEL VL - 13 IS - 2 SP - 1-20 EP - 1-20 PB - MDPI SN - 20751729 KW - nanoparticles KW - silver KW - Agrimonia eupatoria KW - in situ gel UR - https://mdpi-res.com/d_attachment/life/life-13-00573/article_deploy/life-13-00573-v2.pdf?version=1676886955 N2 - Silver nanoparticles (Ag NPs) with antibacterial activity can be prepared in different ways. In our case, we used ecological green synthesis with Agrimonia eupatoria L. The plant extract was used with Ag NPs for the first time to prepare termosensitive in situ gels (ISGs). Such gels are used to heal human or animal skin and mucous membranes, as they can change from a liquid to solid state after application. Ag NPs were characterized with various techniques (FTIR, TEM, size distribution, zeta potential) and their antibacterial activity was tested against Staphylococcus aureus and Escherichia coli. In accordance with the TEM data, we prepared monodispersed spherical Ag NPs with an average size of about 20 nm. Organic active compounds from Agrimonia eupatoria L. were found on their surfaces using FTIR spectroscopy. Surprisingly, only the in situ gel with Ag NPs showed antibacterial activity against Escherichia coli, while Ag NPs alone did not. Ag NPs prepared via green synthesis using plants with medicinal properties and incorporated into ISGs have great potential for wound healing due to the antibacterial activity of Ag NPs and the dermatological activity of organic substances from plants. ER -
BALAZOVA, Ludmila, Tomáš WOLASCHKA, Simona ROHAĽOVÁ, Nina DANEU, Martin STAHORSKY, Aneta SALAYOVA, Ludmila TKACIKOVA and Jarmila EFTIMOVA. In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity. \textit{LIFE-BASEL}. BASEL: MDPI, 2023, vol.~13, No~2, p.~1-20. ISSN~2075-1729. Available from: https://dx.doi.org/10.3390/life13020573.
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