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@proceedings{2277437, author = {Doležalová, Irena and Koriťáková, Eva and Chladek, J. and Jurková, Tereza and Chrastina, Jan and Jurak, P. and Brázdil, Milan}, booktitle = {8th Congress of the European-Academy-of-Neurology (EAN)}, keywords = {EEG; epileptic patients; vagal nerve stimulation}, language = {eng}, title = {Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls?}, url = {https://onlinelibrary.wiley.com/doi/epdf/10.1111/ene.15466}, year = {2022} }
TY - CONF ID - 2277437 AU - Doležalová, Irena - Koriťáková, Eva - Chladek, J. - Jurková, Tereza - Chrastina, Jan - Jurak, P. - Brázdil, Milan PY - 2022 TI - Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls? KW - EEG KW - epileptic patients KW - vagal nerve stimulation UR - https://onlinelibrary.wiley.com/doi/epdf/10.1111/ene.15466 N2 - Background and aims: The presented work is based on the results of our published work, in which we focused on the VNS efficacy prediction in patients with drug-resistant epilepsy. We found that there are differences in power spectra between VNS responders and non-responders. We asked two more questions. Are there differences between the epileptic patients with VNS and healthy controls? Do the EEG power spectra in healthy controls resemble more responders or non-responders to VNS therapy? Methods: We identified retrospectively EEG recording in epileptic patients with VNS and in healthy controls. The epileptic patients were classified based on the VNS efficacy as responder and non-responders EEG was segmented into several time-intervals (resting-state, eyes-opening 1, resting state, photic stimulation, hyperventilation, eyes opening 2, resting state 3 and resting state) and frequency bands. Subsequently, we established relative EEG power spectra in pre-defined frequency bands and time-intervals. Results: We identified EEG in 56 healthy controls and in 60 epileptic patients with VNS (35 responders, 25 non-responders). When compared healthy controls and epileptic patients, we identified EEG power spectra differences in theta (eyes-opening 1, 2), alpha (eyes-opening 1,2) and beta frequency range (eyes-opening 1). When compared responders to VNS therapy and healthy controls, we found more significant differences than in non-responders. ER -
DOLEŽALOVÁ, Irena, Eva KORIŤÁKOVÁ, J. CHLADEK, Tereza JURKOVÁ, Jan CHRASTINA, P. JURAK and Milan BRÁZDIL. Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls? In \textit{8th Congress of the European-Academy-of-Neurology (EAN)}. 2022. ISSN~1351-5101.
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