Predictive factors of multiple sclerosis relapse after the
first demyelinating event: A 5-year follow-up

J 2023

Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up

KOLČAVA, Jan, Ondřej PELÍŠEK and Eva VLČKOVÁ

Basic information

Original name

Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up

Authors

KOLČAVA, Jan (203 Czech Republic, belonging to the institution), Ondřej PELÍŠEK (203 Czech Republic, belonging to the institution) and Eva VLČKOVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

MULTIPLE SCLEROSIS AND RELATED DISORDERS, OXFORD, ELSEVIER SCI LTD, 2023, 2211-0348

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.000 in 2022

RIV identification code

RIV/00216224:14110/23:00130653

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.msard.2023.104566

UT WoS

000940954500001

Keywords in English

Clinically isolated syndrome; Magnetic resonance imaging; Multiple sclerosis; Oligoclonal bands; Demyelinating diseases

Abstract

V originále

There is a growing need to discover the characteristics that predict prognostic factors after the first demyelin-ating event. In this study of 141 patients that met the 2017 McDonald criteria, a higher number of oligoclonal bands, cervical spinal cord demyelinating lesions, and sensory involvement were identified as independent predictors of the second demyelinating event during the 5-year follow-up period in patients who experienced the first demyelinating event. The identification of the aforementioned risk variables will make it possible to identify patients who are more likely to exhibit early second demyelinating event, implying more frequent monitoring and consideration of early application of highly effective disease-modifying treatment.

Links

MUNI/A/1186/2022, interní kód MU

Name: Diagnostika a patofyziologie neuropatické bolesti a dalších symptomů a komorbidit neurologických onemocnění

Investor: Masaryk University

Citovat

KOLČAVA, Jan, Ondřej PELÍŠEK and Eva VLČKOVÁ. Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up. MULTIPLE SCLEROSIS AND RELATED DISORDERS. OXFORD: ELSEVIER SCI LTD, 2023, vol. 71, March 2023, p. 1-3. ISSN 2211-0348. Available from: https://dx.doi.org/10.1016/j.msard.2023.104566.

@article{2278168,
   author = {Kolčava, Jan and Pelíšek, Ondřej and Vlčková, Eva},
   article_location = {OXFORD},
   article_number = {March 2023},
   doi = {http://dx.doi.org/10.1016/j.msard.2023.104566},
   keywords = {Clinically isolated syndrome; Magnetic resonance imaging; Multiple sclerosis; Oligoclonal bands; Demyelinating diseases},
   language = {eng},
   issn = {2211-0348},
   journal = {MULTIPLE SCLEROSIS AND RELATED DISORDERS},
   title = {Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up},
   url = {https://www.sciencedirect.com/science/article/pii/S2211034823000706?via%3Dihub},
   volume = {71},
   year = {2023}
}

TY  - JOUR
ID  - 2278168
AU  - Kolčava, Jan - Pelíšek, Ondřej - Vlčková, Eva
PY  - 2023
TI  - Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up
JF  - MULTIPLE SCLEROSIS AND RELATED DISORDERS
VL  - 71
IS  - March 2023
SP  - 1-3
EP  - 1-3
PB  - ELSEVIER SCI LTD
SN  - 22110348
KW  - Clinically isolated syndrome
KW  - Magnetic resonance imaging
KW  - Multiple sclerosis
KW  - Oligoclonal bands
KW  - Demyelinating diseases
UR  - https://www.sciencedirect.com/science/article/pii/S2211034823000706?via%3Dihub
N2  - There is a growing need to discover the characteristics that predict prognostic factors after the first demyelin-ating event. In this study of 141 patients that met the 2017 McDonald criteria, a higher number of oligoclonal bands, cervical spinal cord demyelinating lesions, and sensory involvement were identified as independent predictors of the second demyelinating event during the 5-year follow-up period in patients who experienced the first demyelinating event. The identification of the aforementioned risk variables will make it possible to identify patients who are more likely to exhibit early second demyelinating event, implying more frequent monitoring and consideration of early application of highly effective disease-modifying treatment.
ER  -

KOLČAVA, Jan, Ondřej PELÍŠEK and Eva VLČKOVÁ. Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up. \textit{MULTIPLE SCLEROSIS AND RELATED DISORDERS}. OXFORD: ELSEVIER SCI LTD, 2023, vol.~71, March 2023, p.~1-3. ISSN~2211-0348. Available from: https://dx.doi.org/10.1016/j.msard.2023.104566.

Detailed Information on Publication Record