KOLČAVA, Jan, Ondřej PELÍŠEK and Eva VLČKOVÁ. Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up. MULTIPLE SCLEROSIS AND RELATED DISORDERS. OXFORD: ELSEVIER SCI LTD, 2023, vol. 71, March 2023, p. 1-3. ISSN 2211-0348. Available from: https://dx.doi.org/10.1016/j.msard.2023.104566.
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Basic information
Original name Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up
Authors KOLČAVA, Jan (203 Czech Republic, belonging to the institution), Ondřej PELÍŠEK (203 Czech Republic, belonging to the institution) and Eva VLČKOVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition MULTIPLE SCLEROSIS AND RELATED DISORDERS, OXFORD, ELSEVIER SCI LTD, 2023, 2211-0348.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.000 in 2022
RIV identification code RIV/00216224:14110/23:00130653
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.msard.2023.104566
UT WoS 000940954500001
Keywords in English Clinically isolated syndrome; Magnetic resonance imaging; Multiple sclerosis; Oligoclonal bands; Demyelinating diseases
Tags 14110221, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 27/4/2023 09:44.
Abstract
There is a growing need to discover the characteristics that predict prognostic factors after the first demyelin-ating event. In this study of 141 patients that met the 2017 McDonald criteria, a higher number of oligoclonal bands, cervical spinal cord demyelinating lesions, and sensory involvement were identified as independent predictors of the second demyelinating event during the 5-year follow-up period in patients who experienced the first demyelinating event. The identification of the aforementioned risk variables will make it possible to identify patients who are more likely to exhibit early second demyelinating event, implying more frequent monitoring and consideration of early application of highly effective disease-modifying treatment.
Links
MUNI/A/1186/2022, interní kód MUName: Diagnostika a patofyziologie neuropatické bolesti a dalších symptomů a komorbidit neurologických onemocnění
Investor: Masaryk University
PrintDisplayed: 8/8/2024 00:27