EDWARDS, Christopher, Brian DRUMM, James E SIEGLER, Wouter J SCHONEWILLE, Piers KLEIN, Xiaochuan HUO, Yimin CHEN, Mohamad ABDALKADER, Muhammad M QURESHI, Daniel STRBIAN, Xinfeng LIU, Wei HU, Xunming JI, Chuanhui LI, Urs FISCHER, Simon NAGEL, Volker PUETZ, Patrik MICHEL, Fana ALEMSEGED, Simona SACCO, Hiroshi YAMAGAMI, Shadi YAGHI, Davide STRAMBO, Espen Saxhaug KRISTOFFERSEN, Else C SANDSET, Robert MIKULÍK, Georgios TSIVGOULIS, Hesham E MASOUD, de Sousa Diana AGUIAR, Joao Pedro MARTO, Kyriakos LOBOTESIS, Dylan ROI, Anne BERBERICH, Jelle DEMEESTERE, Thomas R MEINEL, Rodrigo RIVERA, Sven POLI, Mai Duy TON, Yuyou ZHU, Fengli LI, Hongfei SANG, Goetz THOMALLA, Mark PARSONS, Bruce C V CAMPBELL, Osama O ZAIDAT, Hui-Sheng CHEN, Thalia S FIELD, Jean RAYMOND, Johannes KAESMACHER, Raul G NOGUEIRA, Tudor G JOVIN, Dapeng SUN, Raynald LIU, Adnan I QURESHI, Zhongming QIU, Zhongrong MIAO, Soma BANERJEE and Thanh N NGUYEN. Basilar artery occlusion management: Specialist perspectives from an international survey. Journal of Neuroimaging. Hoboken: Wiley-Blackwell, 2023, vol. 33, No 3, p. 422-433. ISSN 1051-2284. Available from: https://dx.doi.org/10.1111/jon.13084.
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Basic information
Original name Basilar artery occlusion management: Specialist perspectives from an international survey
Authors EDWARDS, Christopher, Brian DRUMM, James E SIEGLER, Wouter J SCHONEWILLE, Piers KLEIN, Xiaochuan HUO, Yimin CHEN, Mohamad ABDALKADER, Muhammad M QURESHI, Daniel STRBIAN, Xinfeng LIU, Wei HU, Xunming JI, Chuanhui LI, Urs FISCHER, Simon NAGEL, Volker PUETZ, Patrik MICHEL, Fana ALEMSEGED, Simona SACCO, Hiroshi YAMAGAMI, Shadi YAGHI, Davide STRAMBO, Espen Saxhaug KRISTOFFERSEN, Else C SANDSET, Robert MIKULÍK (203 Czech Republic, belonging to the institution), Georgios TSIVGOULIS, Hesham E MASOUD, de Sousa Diana AGUIAR, Joao Pedro MARTO, Kyriakos LOBOTESIS, Dylan ROI, Anne BERBERICH, Jelle DEMEESTERE, Thomas R MEINEL, Rodrigo RIVERA, Sven POLI, Mai Duy TON, Yuyou ZHU, Fengli LI, Hongfei SANG, Goetz THOMALLA, Mark PARSONS, Bruce C V CAMPBELL, Osama O ZAIDAT, Hui-Sheng CHEN, Thalia S FIELD, Jean RAYMOND, Johannes KAESMACHER, Raul G NOGUEIRA, Tudor G JOVIN, Dapeng SUN, Raynald LIU, Adnan I QURESHI, Zhongming QIU, Zhongrong MIAO, Soma BANERJEE and Thanh N NGUYEN (guarantor).
Edition Journal of Neuroimaging, Hoboken, Wiley-Blackwell, 2023, 1051-2284.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.400 in 2022
RIV identification code RIV/00216224:14110/23:00130696
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1111/jon.13084
UT WoS 000940458800001
Keywords in English basilar artery occlusion; endovascular therapy; intravenous thrombolysis; mechanical thrombectomy
Tags 14110127, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 30/1/2024 11:43.
Abstract
Background and PurposeTwo early basilar artery occlusion (BAO) randomized controlled trials did not establish the superiority of endovascular thrombectomy (EVT) over medical management. While many providers continue to recommend EVT for acute BAO, perceptions of equipoise in randomizing patients with BAO to EVT versus medical management may differ between clinician specialties. MethodsWe conducted an international survey (January 18, 2022 to March 31, 2022) regarding management strategies in acute BAO prior to the announcement of two trials indicating the superiority of EVT, and compared responses between interventionalists (INTs) and non-interventionalists (nINTs). Selection practices for routine EVT and perceptions of equipoise regarding randomizing to medical management based on neuroimaging and clinical features were compared between the two groups using descriptive statistics. ResultsAmong the 1245 respondents (nINTs = 702), INTs more commonly believed that EVT was superior to medical management in acute BAO (98.5% vs. 95.1%, p < .01). A similar proportion of INTs and nINTs responded that they would not randomize a patient with BAO to EVT (29.4% vs. 26.7%), or that they would only under specific clinical circumstances (p = .45). Among respondents who would recommend EVT for BAO, there was no difference in the maximum prestroke disability, minimum stroke severity, or infarct burden on computed tomography between the two groups (p > .05), although nINTs more commonly preferred perfusion imaging (24.2% vs. 19.7%, p = .04). Among respondents who indicated they would randomize to medical management, INTs were more likely to randomize when the National Institutes of Health Stroke Scale was >= 10 (15.9% vs. 6.9%, p < .01). ConclusionsFollowing the publication of two neutral clinical trials in BAO EVT, most stroke providers believed EVT to be superior to medical management in carefully selected patients, with most indicating they would not randomize a BAO patient to medical treatment. There were small differences in preference for advanced neuroimaging for patient selection, although these preferences were unsupported by clinical trial data at the time of the survey.
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