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@proceedings{2279578,
author = {Souralová, Tereza and Ventruba, Pavel and Ješeta, Michal and Řeháková, Daniela and Hampl, Aleš and Koutná, Irena},
booktitle = {Standardizing Stem Cell Core Facilities in Europe: a CorEuStem Symposium, Lisbon, Portugal},
keywords = {human embryonic stem cells; quality control},
language = {eng},
title = {Quality control of clinical-grade human embryonic stem cells},
year = {2023}
}
TY - CONF
ID - 2279578
AU - Souralová, Tereza - Ventruba, Pavel - Ješeta, Michal - Řeháková, Daniela - Hampl, Aleš - Koutná, Irena
PY - 2023
TI - Quality control of clinical-grade human embryonic stem cells
KW - human embryonic stem cells
KW - quality control
N2 - Human embryonic stem cells are able to differentiate into every cell type in the human body making them a tremendous cell source for regenerative medicine. However, the production of human embryonic stem cell lines for clinical use is challenging as clean rooms, highly-qualified personnel, and standard operating procedures for both manufacture and quality control are required. Here we present the quality control of clinical-grade hESC lines that were derived in xeno-free, feeder-free conditions, and according to current good manufacturing practices. In-depth quality control provides essential information about the safety, pluripotency, and differentiation potential of lines and it is a necessary component of new clinical-grade hESC line establishment.
ER -
SOURALOVÁ, Tereza, Pavel VENTRUBA, Michal JEŠETA, Daniela ŘEHÁKOVÁ, Aleš HAMPL and Irena KOUTNÁ. Quality control of clinical-grade human embryonic stem cells. In \textit{Standardizing Stem Cell Core Facilities in Europe: a CorEuStem Symposium, Lisbon, Portugal}. 2023.
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