Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass
Spectrometry: Toward the Imaging of Individual Nanoparticles

J 2023

Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles

PRYSIAZHNYI, Vadym, Antonín BEDNAŘÍK, Michal ŽALUD, Veronika HEGROVÁ, Jan NEUMAN et. al.

Basic information

Original name

Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles

Authors

PRYSIAZHNYI, Vadym (203 Czech Republic, belonging to the institution), Antonín BEDNAŘÍK (203 Czech Republic, belonging to the institution), Michal ŽALUD (203 Czech Republic, belonging to the institution), Veronika HEGROVÁ (203 Czech Republic), Jan NEUMAN (203 Czech Republic) and Jan PREISLER (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of the American Society for Mass Spectrometry, American Chemical Society, 2023, 1044-0305

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.200 in 2022

RIV identification code

RIV/00216224:14310/23:00130754

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1021/jasms.2c00300

UT WoS

000953993900001

Keywords in English

Gold; Ions; Lasers; Metal nanoparticles; Suspensions

Abstract

V originále

This study focuses on mapping the spatial distribution of Au nanoparticles (NPs) by laser desorption/ionization mass spectrometry imaging (LDI MSI). Laser interaction with NPs and associated phenomena, such as change of shape, melting, migration, and release of Au ions, are explored at the single particle level. Arrays of dried droplets containing low numbers of spatially segregated NPs were reproducibly prepared by automated drop-on-demand piezo-dispensing and analyzed by LDI MSI using an ultrahigh resolution orbital trapping instrument. To enhance the signal from NPs, an in source gas-phase chemical reaction of generated Au ions with xylene was employed. The developed technique allowed the detecting, chemical characterization, and mapping of the spatial distribution of Au NPs; the ion signals were detected from as low as ten 50 nm Au NPs on a pixel. Furthermore, the Au NP melting dynamics under laser irradiation was monitored by correlative atomic force microscopy (AFM) and scanning electron microscopy (SEM). AFM measurements of Au NPs before and after LDI MSI analysis revealed changes in NP shape from a sphere to a half-ellipsoid and total volume reduction of NPs down to 45% of their initial volume.

Links

GA21-12262S, research and development project

Name: Nanočásticové sondy pro zobrazovací hmotnostní spektrometrii

Investor: Czech Science Foundation

MUNI/A/1421/2022, interní kód MU

Name: Vývoj metod a instrumentace pro analýzu biologicky významných látek 2023

Investor: Masaryk University

90127, large research infrastructures

Name: CIISB II

Citovat

PRYSIAZHNYI, Vadym, Antonín BEDNAŘÍK, Michal ŽALUD, Veronika HEGROVÁ, Jan NEUMAN and Jan PREISLER. Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles. Journal of the American Society for Mass Spectrometry. American Chemical Society, 2023, vol. 34, No 4, p. 570-578. ISSN 1044-0305. Available from: https://dx.doi.org/10.1021/jasms.2c00300.

@article{2281538,
   author = {Prysiazhnyi, Vadym and Bednařík, Antonín and Žalud, Michal and Hegrová, Veronika and Neuman, Jan and Preisler, Jan},
   article_number = {4},
   doi = {http://dx.doi.org/10.1021/jasms.2c00300},
   keywords = {Gold; Ions; Lasers; Metal nanoparticles; Suspensions},
   language = {eng},
   issn = {1044-0305},
   journal = {Journal of the American Society for Mass Spectrometry},
   title = {Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles},
   url = {https://pubs.acs.org/doi/10.1021/jasms.2c00300},
   volume = {34},
   year = {2023}
}

TY  - JOUR
ID  - 2281538
AU  - Prysiazhnyi, Vadym - Bednařík, Antonín - Žalud, Michal - Hegrová, Veronika - Neuman, Jan - Preisler, Jan
PY  - 2023
TI  - Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles
JF  - Journal of the American Society for Mass Spectrometry
VL  - 34
IS  - 4
SP  - 570-578
EP  - 570-578
PB  - American Chemical Society
SN  - 10440305
KW  - Gold
KW  - Ions
KW  - Lasers
KW  - Metal nanoparticles
KW  - Suspensions
UR  - https://pubs.acs.org/doi/10.1021/jasms.2c00300
N2  - This study focuses on mapping the spatial distribution of Au nanoparticles (NPs) by laser desorption/ionization mass spectrometry imaging (LDI MSI). Laser interaction with NPs and associated phenomena, such as change of shape, melting, migration, and release of Au ions, are explored at the single particle level. Arrays of dried droplets containing low numbers of spatially segregated NPs were reproducibly prepared by automated drop-on-demand piezo-dispensing and analyzed by LDI MSI using an ultrahigh resolution orbital trapping instrument. To enhance the signal from NPs, an in source gas-phase chemical reaction of generated Au ions with xylene was employed. The developed technique allowed the detecting, chemical characterization, and mapping of the spatial distribution of Au NPs; the ion signals were detected from as low as ten 50 nm Au NPs on a pixel. Furthermore, the Au NP melting dynamics under laser irradiation was monitored by correlative atomic force microscopy (AFM) and scanning electron microscopy (SEM). AFM measurements of Au NPs before and after LDI MSI analysis revealed changes in NP shape from a sphere to a half-ellipsoid and total volume reduction of NPs down to 45% of their initial volume.
ER  -

PRYSIAZHNYI, Vadym, Antonín BEDNAŘÍK, Michal ŽALUD, Veronika HEGROVÁ, Jan NEUMAN and Jan PREISLER. Fate of Gold Nanoparticles in Laser Desorption/Ionization Mass Spectrometry: Toward the Imaging of Individual Nanoparticles. \textit{Journal of the American Society for Mass Spectrometry}. American Chemical Society, 2023, vol.~34, No~4, p.~570-578. ISSN~1044-0305. Available from: https://dx.doi.org/10.1021/jasms.2c00300.

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