Detailed Information on Publication Record
2023
Effect of titanium nanostructured surface on fibroblast behavior
VRCHOVECKÁ, Kateřina, Jan KUTA, Martin UHER, Jan PŘIBYL, Monika PÁVKOVÁ GOLDBERGOVÁ et. al.Basic information
Original name
Effect of titanium nanostructured surface on fibroblast behavior
Authors
VRCHOVECKÁ, Kateřina (203 Czech Republic, belonging to the institution), Jan KUTA (203 Czech Republic, belonging to the institution), Martin UHER (203 Czech Republic, belonging to the institution), Jan PŘIBYL (203 Czech Republic, guarantor, belonging to the institution) and Monika PÁVKOVÁ GOLDBERGOVÁ (203 Czech Republic, belonging to the institution)
Edition
Journal of Biomedical Materials Research Part A, HOBOKEN, WILEY111, 2023, 1549-3296
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
21002 Nano-processes ;
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 4.900 in 2022
RIV identification code
RIV/00216224:14110/23:00130787
Organization unit
Faculty of Medicine
UT WoS
000958302100001
Keywords in English
cell morphology; cell viability; fibroblast; ion release; titanium nanotubes
Tags
International impact, Reviewed
Změněno: 18/10/2024 13:45, Ing. Jana Kuchtová
Abstract
V originále
As the consumption of implants increases, so do the requirements for individual types of implants, for example, improved biocompatibility or longevity. Therefore, the nano-modification of the titanium surface is often chosen. The aim was to characterize the modified surface with a focus on medical applications. The titanium surface was modified by the anodic oxidation method to form nanotubes. Subsequently, the material was characterized and analyzed for medical applications—surface morphology, surface wettability, chemical composition, and release of ions into biological fluids. A human gingival fibroblasts (HGFb) cell line was used in the viability study. A homogeneous layer of nanotubes of defined dimensions was formed on the titanium surface, ensuring the material's biocompatibility—the preparation conditions influence the resulting properties of the nanostructured surface. Nanostructured titanium exhibited more suitable characteristics (e.g., wettability, roughness, ion release) for biological applications than compared to pure titanium. It was possible to understand the behavior of the modified layer on the titanium surface and its effect on cell behavior. Another contribution of this work is the combination of material characterization (ion release) with the study of cytocompatibility (direct contact of cells with metals).
Links
EF17_043/0009632, research and development project |
| ||
EF18_046/0015974, research and development project |
| ||
GA20-11321S, research and development project |
| ||
LM2018121, research and development project |
| ||
MUNI/A/1370/2022, interní kód MU |
| ||
NU20-08-00149, research and development project |
| ||
90121, large research infrastructures |
| ||
90242, large research infrastructures |
|