PAVLOVA, Iveta and Jana RUDÁ. Brain metabolic derangements examined using 1H MRS and their (in)consistency among different rodent models of depression. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2023, vol. 127, December 2023, p. 1-17. ISSN 0278-5846. Available from: https://dx.doi.org/10.1016/j.pnpbp.2023.110808.
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Basic information
Original name Brain metabolic derangements examined using 1H MRS and their (in)consistency among different rodent models of depression
Name in Czech Metabolické změny mozku zkoumané pomocí 1H MRS a jejich (ne)konzistence mezi různými modely deprese u hlodavců
Authors PAVLOVA, Iveta (688 Serbia, belonging to the institution) and Jana RUDÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2023, 0278-5846.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 5.600 in 2022
RIV identification code RIV/00216224:14110/23:00130976
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.pnpbp.2023.110808
UT WoS 001058514600001
Keywords in English Animal models Depression Proton magnetic resonance spectroscopy Metabolites
Tags 14110516, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 25/1/2024 15:14.
Abstract
This review summarises the current knowledge of 1H MRS findings from rodent models of MDD, assesses the results from both a biological and a technical perspective, and identifies the main sources of bias. From a technical point of view, bias-introducing factors are the diversity of the measured volumes and their positioning in the brain, the data processing, and the metabolite concentration expression.
Links
LM2018129, research and development projectName: Národní infrastruktura pro biologické a medicínské zobrazování Czech-BioImaging
Investor: Ministry of Education, Youth and Sports of the CR
LM2023050, research and development projectName: Národní infrastruktura pro biologické a medicínské zobrazování
Investor: Ministry of Education, Youth and Sports of the CR, Czech BioImaging: National research infrastructure for biological and medical imaging
MUNI/A/1342/2022, interní kód MUName: Preklinický a klinický výzkum v oblasti farmakokinetiky, neuropsychofarmakologie a personalizované farmakoterapie v onkologii
Investor: Masaryk University, Preclinical and clinical research in pharmacokinetics, neuropsychopharmacology and personalized pharmacotherapy in oncology
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