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@proceedings{2293215, author = {Škovranová, Gabriela and Molčanová, Lenka and Klančnik, Anja and Jug, Blaž and SmoleandMožina, Sonja and Sychrová, Alice}, booktitle = {18th Warsaw International Medical Congress, 21st - 23rd April 2023}, keywords = {antimicrobial activity; eradication; Paulownia tomentosa; quorum-sensing; Staphylococcus aureus}, language = {eng}, title = {Paulownia tomentosa extracts fighting against staphylococcal biofilm formation}, url = {https://wimc.wum.edu.pl/18th-wimc-abstract-book/}, year = {2023} }
TY - CONF ID - 2293215 AU - Škovranová, Gabriela - Molčanová, Lenka - Klančnik, Anja - Jug, Blaž - Smole-Možina, Sonja - Sychrová, Alice PY - 2023 TI - Paulownia tomentosa extracts fighting against staphylococcal biofilm formation KW - antimicrobial activity KW - eradication KW - Paulownia tomentosa KW - quorum-sensing KW - Staphylococcus aureus UR - https://wimc.wum.edu.pl/18th-wimc-abstract-book/ N2 - Staphylococcus aureus is challenging to treat especially if biofilm occurs. Prenylated phenolics provide a significant source of potent antimicrobial agents. Ethanolic extract of Paulownia tomentosa was rich in active compounds, but prenylated flavonoids were dominant in the chloroform fraction. MIC of ethanolic extract, chloroform fraction, and three flavonoids showed significant antimicrobial activity, while lower concentrations prolonged the lag phase. Selected compounds reduced the adhesion of bacteria to the abiotic surface, and also the measurement of bioluminescence showed inhibition of intercellular signaling in bacterial suspension treated with plant formulations. ER -
ŠKOVRANOVÁ, Gabriela, Lenka MOLČANOVÁ, Anja KLANČNIK, Blaž JUG, Sonja SMOLE-MOŽINA and Alice SYCHROVÁ. Paulownia tomentosa extracts fighting against staphylococcal biofilm formation. In \textit{18th Warsaw International Medical Congress, 21st - 23rd April 2023}. 2023.
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