Detailed Information on Publication Record
2023
The effect of intrapartum antibiotics prophylaxis on neonatal gut and oral bacteriome
PIVRNCOVÁ, Eliška, Iva KOTÁSKOVÁ, Lucie BUREŠOVÁ, Lenka ANDRÝSKOVÁ, Pavel PILER et. al.Basic information
Original name
The effect of intrapartum antibiotics prophylaxis on neonatal gut and oral bacteriome
Authors
PIVRNCOVÁ, Eliška (203 Czech Republic, belonging to the institution), Iva KOTÁSKOVÁ (203 Czech Republic), Lucie BUREŠOVÁ (203 Czech Republic), Lenka ANDRÝSKOVÁ (203 Czech Republic), Pavel PILER (203 Czech Republic), Petr JANKŮ (203 Czech Republic), Ivo BOREK (203 Czech Republic), Jana KLÁNOVÁ (203 Czech Republic), Petra VÍDEŇSKÁ (203 Czech Republic), Eva BUDINSKÁ (703 Slovakia) and Petra BOŘILOVÁ LINHARTOVÁ (203 Czech Republic, guarantor)
Edition
RECETOX PhD Conference 2023, 2023
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
10608 Biochemistry and molecular biology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/23:00131175
Organization unit
Faculty of Science
Keywords in English
antibiotics prophylaxis;neonatal gut;oral bacteriome
Změněno: 7/7/2023 11:13, Mgr. Terezie Slámová
Abstract
V originále
The administration of intrapartum antibiotics prophylaxis (IAP) is commonly used in cesarean section and for the prevention of early-onset Group-B-streptococci infection. Since IAP may influence the microbiome development in neonates, our pilot study aimed to characterize the gut and oral bacteriome changes between neonates grouped according to their exposure to antibiotics during the delivery and sampling time in the first week of their life. 16S rDNA sequencing revealed differences in bacterial abundance in transitional stool samples, but not in meconium samples. Moreover, IAP influenced the oral bacteriome of neonates within 48 hours after birth. However, the effect of IAP on oral bacteriome seems to be suppressed later in the first week of their life.
Links
EF17_043/0009632, research and development project |
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LM2018132, research and development project |
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LM2018140, research and development project |
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LM2023069, research and development project |
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