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@article{2296988,
author = {Dite, Petr and Precechtelova, Marie and Bojkova, Martina and Lovecek, Martin and Ambroz, Radek and Martinek, Arnost and Dolina, Jiří},
article_location = {Olomouc},
article_number = {2},
doi = {http://dx.doi.org/10.5507/bp.2023.019},
keywords = {pancreatic pain; painless form of pancreatitis; diabetes mellitus; pancreatic calcifications; exocrine insufficiency},
language = {eng},
issn = {1213-8118},
journal = {Biomedical Papers, Olomouc: Palacky University},
title = {Painless form of chronic pancreatitis-multicentre study},
url = {https://biomed.papers.upol.cz/artkey/bio-202302-0009_painless-form-of-chronic-pancreatitis-multicentre-study.php},
volume = {167},
year = {2023}
}
TY - JOUR
ID - 2296988
AU - Dite, Petr - Precechtelova, Marie - Bojkova, Martina - Lovecek, Martin - Ambroz, Radek - Martinek, Arnost - Dolina, Jiří
PY - 2023
TI - Painless form of chronic pancreatitis-multicentre study
JF - Biomedical Papers, Olomouc: Palacky University
VL - 167
IS - 2
SP - 157-161
EP - 157-161
PB - Palacky University
SN - 12138118
KW - pancreatic pain
KW - painless form of pancreatitis
KW - diabetes mellitus
KW - pancreatic calcifications
KW - exocrine insufficiency
UR - https://biomed.papers.upol.cz/artkey/bio-202302-0009_painless-form-of-chronic-pancreatitis-multicentre-study.php
N2 - Background. The painless form of chronic pancreatitis is one of the rarer forms of the disease. While 80% to 90% of all chronic pancreatitis cases have abdominal pain as their clinical symptom, a smaller proportion of persons with chronic pancreatitis do not report typical pain. This form of the disease is often associated with exocrine and endocrine pancreatic insufficiency and weight loss, but the absence of pain symptoms may initially lead to misdiagnosis. Methods. In a cohort of 257 people with chronic pancreatitis, the painless form was diagnosed in 30 individuals (11.6%), with an average age of 56 years and a predominance of men (71.4%). Thirty-eight percent were non-smokers and 47.6% of patients smoked up to 10 cigarettes per day. Alcohol intake of less than 40 g per day was reported by 61.9% of subjects. A quarter were moderately overweight, with a mean BMI of 26.5. Newly diagnosed diabetes mellitus had 25.7% of the subjects.Results. A frequent finding was the demonstration of morphological changes, with calcifications found in 85,7% and dilatation of the pancreatic duct greater than 6.0 mm in 66%. A surprising finding was the presence of metabolic syndrome in 42.8% and the most frequent finding was the demonstration of decreased external pancreatic secretion (90%).Conclusion. Painless chronic pancreatitis is usually treated conservatively. We demonstrate a subset of 28 patients with painless chronic pancreatitis treated surgically. Most frequent indications were benign stenosis of the intrapancreatic bile duct and stenosis of the pancreatic duct. Although approximately 1 in 10 people with chronic pancreatitis present with a painless form of it, so that the form of the disease is described as rare, this does not change the fact that management of these people is still not optimal.
ER -
DITE, Petr, Marie PRECECHTELOVA, Martina BOJKOVA, Martin LOVECEK, Radek AMBROZ, Arnost MARTINEK and Jiří DOLINA. Painless form of chronic pancreatitis-multicentre study. \textit{Biomedical Papers, Olomouc: Palacky University}. Olomouc: Palacky University, 2023, vol.~167, No~2, p.~157-161. ISSN~1213-8118. Available from: https://dx.doi.org/10.5507/bp.2023.019.
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