MACKŮ, Jan, Kateřina KUBOVÁ and Martina ČUBOVÁ URBANOVÁ. Solid-State NMR: The Useful Tool in The Development of Thymol Self-Emulsifying Pellets. In Student scientific conference MUNI PHARM doctoral students 2022. 2022. ISBN 978-80-280-0105-6.
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Basic information
Original name Solid-State NMR: The Useful Tool in The Development of Thymol Self-Emulsifying Pellets
Name in Czech NMR v pevné fázi: užitečný nástroj při vývoji samoemulgujících pelet s obsahemthymolu
Authors MACKŮ, Jan (203 Czech Republic, belonging to the institution), Kateřina KUBOVÁ (203 Czech Republic, belonging to the institution) and Martina ČUBOVÁ URBANOVÁ (203 Czech Republic).
Edition Student scientific conference MUNI PHARM doctoral students 2022, 2022.
Other information
Original language English
Type of outcome Presentations at conferences
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Pharmacy
ISBN 978-80-280-0105-6
Keywords (in Czech) samoemulgující systém; thymol; pelety; NMR spektroskopie v pevné fázi
Keywords in English self-emulsifying system; thymol; pellets; solid-state NMR spectroscopy
Tags ÚFT
Changed by Changed by: Mgr. Jan Macků, učo 451414. Changed: 2/5/2024 12:06.
Abstract
Experiment aims on formulation of self-emulsifying pellets, reveals multiple methods of preparation and selects the most industrialy feasible while probing the possible structural differences via ss-NMR spectroscopy. Self-emulsifying pellets were formulated, tested in-vitro and ex-vivo. In-vitro dissolution confirmed that pellets are gastro-resistant. Ex-vivo experiment confirmed that thymol is cummulated in the intestinal wall.
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