Solid-State NMR: The Useful Tool in The Development of Thymol Self-Emulsifying Pellets

MACKŮ, Jan, Kateřina KUBOVÁ and Martina ČUBOVÁ URBANOVÁ. Solid-State NMR: The Useful Tool in The Development of Thymol Self-Emulsifying Pellets. In Student scientific conference MUNI PHARM doctoral students 2022. 2022. ISBN 978-80-280-0105-6.

Basic information

Original name

Solid-State NMR: The Useful Tool in The Development of Thymol Self-Emulsifying Pellets

Name in Czech

NMR v pevné fázi: užitečný nástroj při vývoji samoemulgujících pelet s obsahemthymolu

Authors

MACKŮ, Jan (203 Czech Republic, belonging to the institution), Kateřina KUBOVÁ (203 Czech Republic, belonging to the institution) and Martina ČUBOVÁ URBANOVÁ (203 Czech Republic)

Edition

Student scientific conference MUNI PHARM doctoral students 2022, 2022

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Other information

Language

English

Type of outcome

Prezentace na konferencích

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Pharmacy

ISBN

978-80-280-0105-6

Keywords (in Czech)

samoemulgující systém; thymol; pelety; NMR spektroskopie v pevné fázi

Keywords in English

self-emulsifying system; thymol; pellets; solid-state NMR spectroscopy

Tags

ÚFT

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Abstract

V originále

Experiment aims on formulation of self-emulsifying pellets, reveals multiple methods of preparation and selects the most industrialy feasible while probing the possible structural differences via ss-NMR spectroscopy. Self-emulsifying pellets were formulated, tested in-vitro and ex-vivo. In-vitro dissolution confirmed that pellets are gastro-resistant. Ex-vivo experiment confirmed that thymol is cummulated in the intestinal wall.