Detailed Information on Publication Record
2023
Cortisol in deciduous tooth tissues: A potential metric for assessing stress exposure in archaeological and living populations
QUADE, Leslie, Miroslav KRÁLÍK, Petra BENCÚROVÁ and Erin C. DUNNBasic information
Original name
Cortisol in deciduous tooth tissues: A potential metric for assessing stress exposure in archaeological and living populations
Authors
QUADE, Leslie (840 United States of America, guarantor, belonging to the institution), Miroslav KRÁLÍK (203 Czech Republic, belonging to the institution), Petra BENCÚROVÁ (703 Slovakia, belonging to the institution) and Erin C. DUNN (840 United States of America)
Edition
International Journal of Paleopathology, Elsevier, 2023, 1879-9817
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10700 1.7 Other natural sciences
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 1.200 in 2022
RIV identification code
RIV/00216224:14310/23:00131508
Organization unit
Faculty of Science
UT WoS
001067211900001
Keywords in English
Glucocorticoid Hormones; Dentine; Enamel; Circumpulpal Dentine; Fetus; Dentition
Tags
Tags
International impact, Reviewed
Změněno: 7/3/2024 10:37, Mgr. Eva Dubská
Abstract
V originále
Objective. Cortisol is a glucocorticoid hormone produced by the hypothalamic-pituitary-adrenal axis that is regularly assessed in modern human and non-human populations in saliva, blood, and hair as a measure of stress exposure and stress reactivity. While recent research has detected cortisol concentrations in modern and archaeological permanent dental tissues, the present study assessed human primary (deciduous) teeth for cortisol concentrations. Materials and Methods. Fifty-one dentine and enamel samples from nine modern and 10 archaeological deciduous teeth were analyzed for cortisol concentrations via enzyme-linked immunosorbent assay (ELISA). Results. Detectable concentrations of cortisol were identified in 15 (of 32) dentine and 8 (of 19) enamel samples coming from modern and archaeological deciduous teeth. Conclusions. This study is the first known analysis of cortisol from deciduous dental tissues, demonstrating the potential to identify measurable concentrations. Significance. The ability to analyze deciduous teeth is integral to developing dental cortisol methods with multiple potential future applications, including research on the biological embedding of stress in the skeleton. This study marks a key step in a larger research program to study stress in primary dentition from living and archaeological populations. Limitations. Multiple samples generated cortisol values that were not detectable with ELISA. Minimum quantities of tissue may be required to generate detectable levels of cortisol. Suggestions for Further Research. Future research should include larger sample sizes and consideration of intrinsic biological and extrinsic preservation factors on dental cortisol. Further method validation and alternative methods for assessing dental cortisol are needed.
Links
| EF18_053/0016952, research and development project |
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