Donor nerve selection in free gracilis muscle transfer for
facial reanimation. A systematic review and meta-analysis of
clinical outcomes

J 2023

Donor nerve selection in free gracilis muscle transfer for facial reanimation. A systematic review and meta-analysis of clinical outcomes

BAYEZID, Kadir Can, Marek JOUKAL, Erdem KARABULUT, Jan MACEK, Ludmila MORAVCOVÁ et. al.

Basic information

Original name

Donor nerve selection in free gracilis muscle transfer for facial reanimation. A systematic review and meta-analysis of clinical outcomes

Authors

BAYEZID, Kadir Can (792 Turkey, belonging to the institution), Marek JOUKAL (203 Czech Republic, belonging to the institution), Erdem KARABULUT (792 Turkey), Jan MACEK (203 Czech Republic, belonging to the institution), Ludmila MORAVCOVÁ (203 Czech Republic, belonging to the institution) and Libor STREIT (203 Czech Republic, guarantor, belonging to the institution)

Edition

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, OXFORD, ELSEVIER SCI LTD, 2023, 1748-6815

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.700 in 2022

RIV identification code

RIV/00216224:14110/23:00131589

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.bjps.2023.04.014

UT WoS

001053394100001

Keywords in English

Facial palsy; Facial reanimation; Free gracilis muscle transfer; Dual innervated free gracilis flap

Abstract

V originále

Background: One of the critical factors in facial reanimation is selecting the donor nerve. The most favored neurotizers are the contralateral facial nerve with a cross-face nerve graft (CFNG) and motor nerve to the masseter (MNM). A relatively new dual innervation (DI) method has shown successful results. This study aimed to compare the clinical outcomes of different neurotization strategies for free gracilis muscle transfer (FGMT). Methods: The Scopus and WoS databases were queried with 21 keywords. Three-stage article selection was performed for the systematic review. Articles presenting quantitative data for commissure excursion and facial symmetry were included in meta-analysis, using random-ef- fects model. ROBINS-I tool and Newcastle-Ottawa scale were used to assess bias and study quality. Results: One hundred forty-seven articles containing FGMT were systematically reviewed. Most studies indicated CFNG as the first choice. MNM was primarily indicated in bilateral palsy and in elderly. Clinical outcomes of DI studies were promising. 13 studies including 435 observations (179 CFNG, 182 MNM, 74 DI) were eligible for meta-analysis. The mean change in commissure excursion was 7.15 mm (95% CI: 4.57-9.72) for CFNG, 8.46 mm (95% CI: 6.86-10.06) for MNM, and 5.18 mm (95% CI: 4.01-6.34) for DI. In pairwise comparisons, a significant difference was found between MNM and DI (p = 0.0011), despite the superior outcomes described in DI studies.

Links

MUNI/A/1360/2022, interní kód MU

Name: Evaluace inovativních postupů plastické a rekonstrukční chirurgie III

Investor: Masaryk University, Evaluation of Innovative Procedures in Plastic and Reconstructive Surgery III

MUNI/A/1668/2020, interní kód MU

Name: Evaluace inovativních postupů plastické a rekonstrukční chirurgie (Acronym: KPECH SV 2021)

Investor: Masaryk University

MUNI/11/SUP/01/2020, interní kód MU

Name: Reanimace obličeje při obrně lícního nervu: Zdvojená inervace motorické jednotky v experimentu in vivo

Investor: Masaryk University

Citovat

BAYEZID, Kadir Can, Marek JOUKAL, Erdem KARABULUT, Jan MACEK, Ludmila MORAVCOVÁ and Libor STREIT. Donor nerve selection in free gracilis muscle transfer for facial reanimation. A systematic review and meta-analysis of clinical outcomes. JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY. OXFORD: ELSEVIER SCI LTD, 2023, vol. 82, July 2023, p. 31-47. ISSN 1748-6815. Available from: https://dx.doi.org/10.1016/j.bjps.2023.04.014.

@article{2306560,
   author = {Bayezid, Kadir Can and Joukal, Marek and Karabulut, Erdem and Macek, Jan and Moravcová, Ludmila and Streit, Libor},
   article_location = {OXFORD},
   article_number = {July 2023},
   doi = {http://dx.doi.org/10.1016/j.bjps.2023.04.014},
   keywords = {Facial palsy; Facial reanimation; Free gracilis muscle transfer; Dual innervated free gracilis flap},
   language = {eng},
   issn = {1748-6815},
   journal = {JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY},
   title = {Donor nerve selection in free gracilis muscle transfer for facial reanimation. A systematic review and meta-analysis of clinical outcomes},
   url = {https://www.sciencedirect.com/science/article/pii/S1748681523001638?via%3Dihub},
   volume = {82},
   year = {2023}
}

TY  - JOUR
ID  - 2306560
AU  - Bayezid, Kadir Can - Joukal, Marek - Karabulut, Erdem - Macek, Jan - Moravcová, Ludmila - Streit, Libor
PY  - 2023
TI  - Donor nerve selection in free gracilis muscle transfer for facial reanimation. A systematic review and meta-analysis of clinical outcomes
JF  - JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
VL  - 82
IS  - July 2023
SP  - 31-47
EP  - 31-47
PB  - ELSEVIER SCI LTD
SN  - 17486815
KW  - Facial palsy
KW  - Facial reanimation
KW  - Free gracilis muscle transfer
KW  - Dual innervated free gracilis flap
UR  - https://www.sciencedirect.com/science/article/pii/S1748681523001638?via%3Dihub
N2  - Background: One of the critical factors in facial reanimation is selecting the donor nerve. The most favored neurotizers are the contralateral facial nerve with a cross-face nerve graft (CFNG) and motor nerve to the masseter (MNM). A relatively new dual innervation (DI) method has shown successful results. This study aimed to compare the clinical outcomes of different neurotization strategies for free gracilis muscle transfer (FGMT). Methods: The Scopus and WoS databases were queried with 21 keywords. Three-stage article selection was performed for the systematic review. Articles presenting quantitative data for commissure excursion and facial symmetry were included in meta-analysis, using random-ef- fects model. ROBINS-I tool and Newcastle-Ottawa scale were used to assess bias and study quality. Results: One hundred forty-seven articles containing FGMT were systematically reviewed. Most studies indicated CFNG as the first choice. MNM was primarily indicated in bilateral palsy and in elderly. Clinical outcomes of DI studies were promising. 13 studies including 435 observations (179 CFNG, 182 MNM, 74 DI) were eligible for meta-analysis. The mean change in commissure excursion was 7.15 mm (95% CI: 4.57-9.72) for CFNG, 8.46 mm (95% CI: 6.86-10.06) for MNM, and 5.18 mm (95% CI: 4.01-6.34) for DI. In pairwise comparisons, a significant difference was found between MNM and DI (p = 0.0011), despite the superior outcomes described in DI studies.
ER  -

BAYEZID, Kadir Can, Marek JOUKAL, Erdem KARABULUT, Jan MACEK, Ludmila MORAVCOVÁ and Libor STREIT. Donor nerve selection in free gracilis muscle transfer for facial reanimation. A systematic review and meta-analysis of clinical outcomes. \textit{JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY}. OXFORD: ELSEVIER SCI LTD, 2023, vol.~82, July 2023, p.~31-47. ISSN~1748-6815. Available from: https://dx.doi.org/10.1016/j.bjps.2023.04.014.

Detailed Information on Publication Record