ŘIHÁČKOVÁ, Eva, Michal ŘIHÁČEK, Mária VYSKOČILOVÁ, Dalibor VALÍK and Lubomír ELBL. Revisiting treatment-related cardiotoxicity in patients with malignant lymphoma-a review and prospects for the future. Frontiers in Cardiovascular Medicine. Lausanne: Frontiers, 2023, vol. 10, August 2023, p. 1-16. ISSN 2297-055X. Available from: https://dx.doi.org/10.3389/fcvm.2023.1243531.
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Basic information
Original name Revisiting treatment-related cardiotoxicity in patients with malignant lymphoma-a review and prospects for the future
Authors ŘIHÁČKOVÁ, Eva (203 Czech Republic, belonging to the institution), Michal ŘIHÁČEK (203 Czech Republic, belonging to the institution), Mária VYSKOČILOVÁ (703 Slovakia, belonging to the institution), Dalibor VALÍK (203 Czech Republic, belonging to the institution) and Lubomír ELBL (203 Czech Republic, belonging to the institution).
Edition Frontiers in Cardiovascular Medicine, Lausanne, Frontiers, 2023, 2297-055X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.600 in 2022
RIV identification code RIV/00216224:14110/23:00131614
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3389/fcvm.2023.1243531
UT WoS 001064769300001
Keywords in English lymphoma; cardiotoxicity; chemotherapy; modern treatment; prevention; cardiac adverse events
Tags 14110211, 14110512, 14110516, 14110616, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 17/1/2024 11:56.
Abstract
Treatment of malignant lymphoma has for years been represented by many cardiotoxic agents especially anthracyclines, cyclophosphamide, and thoracic irradiation. Although they are in clinical practice for decades, the precise mechanism of cardiotoxicity and effective prevention is still part of the research. At this article we discuss most routinely used anti-cancer drugs in chemotherapeutic regiments for malignant lymphoma with the focus on novel insight on molecular mechanisms of cardiotoxicity. Understanding toxicity at molecular levels may unveil possible targets of cardioprotective supportive therapy or optimization of current therapeutic protocols. Additionally, we review novel specific targeted therapy and its challenges in cardio-oncology.
Links
90249, large research infrastructuresName: CZECRIN IV
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