CHARESHNEU, Aliaksei, Adam MIDLIK, Crina-Maria IONESCU, Alexander ROSE, Vladimír HORSKÝ, Alessio CANTARA, Radka SVOBODOVÁ, Karel BERKA and David SEHNAL. Mol* Volumes and Segmentations: visualization and interpretation of cell imaging data alongside macromolecular structure data and biological annotations. Nucleic Acids Research. Oxford University Press, 2023, vol. 51, W1, p. "W326"-"W330", 5 pp. ISSN 0305-1048. Available from: https://dx.doi.org/10.1093/nar/gkad411.
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Basic information
Original name Mol* Volumes and Segmentations: visualization and interpretation of cell imaging data alongside macromolecular structure data and biological annotations
Authors CHARESHNEU, Aliaksei (112 Belarus, belonging to the institution), Adam MIDLIK (703 Slovakia, belonging to the institution), Crina-Maria IONESCU (203 Czech Republic, belonging to the institution), Alexander ROSE, Vladimír HORSKÝ (203 Czech Republic, belonging to the institution), Alessio CANTARA (380 Italy, belonging to the institution), Radka SVOBODOVÁ (203 Czech Republic, belonging to the institution), Karel BERKA (203 Czech Republic) and David SEHNAL (203 Czech Republic, guarantor, belonging to the institution).
Edition Nucleic Acids Research, Oxford University Press, 2023, 0305-1048.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 14.900 in 2022
RIV identification code RIV/00216224:14310/23:00131662
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1093/nar/gkad411
UT WoS 000989609300001
Keywords in English 3D structure; visualization; biomacromolecules; organelle- and cell-sized models
Tags CF BDMA, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Eva Dubská, učo 77638. Changed: 3/3/2024 14:20.
Abstract
Segmentation helps interpret imaging data in a biological context. With the development of powerful tools for automated segmentation, public repositories for imaging data have added support for sharing and visualizing segmentations, creating the need for interactive web-based visualization of 3D volume segmentations. To address the ongoing challenge of integrating and visualizing multimodal data, we developed Mol* Volumes and Segmentations (Mol*VS), which enables the interactive, web-based visualization of cellular imaging data supported by macromolecular data and biological annotations. Mol*VS is fully integrated into Mol* Viewer, which is already used for visualization by several public repositories. All EMDB and EMPIAR entries with segmentation datasets are accessible via Mol*VS, which supports the visualization of data from a wide range of electron and light microscopy experiments. Additionally, users can run a local instance of Mol*VS to visualize and share custom datasets in generic or application-specific formats including volumes in .ccp4, .mrc, and .map, and segmentations in EMDB-SFF .hff, Amira .am, iMod .mod, and Segger .seg. Mol*VS is open source and freely available at https://molstarvolseg.ncbr.muni.cz/.
Links
GM22-30571M, research and development projectName: Cell*: webová platforma pro vizualizaci, modelování a dynamiku organelových a buněčných struktur (Acronym: Cell*)
Investor: Czech Science Foundation
LM2023054, research and development projectName: e-Infrastruktura CZ
Investor: Ministry of Education, Youth and Sports of the CR
LM2023055, research and development projectName: Česká národní infrastruktura pro biologická data
Investor: Ministry of Education, Youth and Sports of the CR, ELIXIR-CZ: Czech National Infrastructure for Biological Data
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