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@proceedings{2313657, author = {Dvořáková, Martina and Kollár, Peter and Onuščáková, Magdaléna and Bobáľ, Pavel and Kauerová, Tereza}, booktitle = {Student Scientific Conference MUNI PHARM 2022}, keywords = {histone deacetylase inhibitors; vorinostat; hydroxamic acids; histones; apoptosis}, language = {eng}, isbn = {978-80-280-0106-3}, title = {Novel potential histone deacetylase inhibitors and their proapoptotic effects in cancer cells}, url = {https://www.pharm.muni.cz/veda-a-vyzkum/svk/magistersti-studenti/archiv-sborniku/2022}, year = {2022} }
TY - CONF ID - 2313657 AU - Dvořáková, Martina - Kollár, Peter - Onuščáková, Magdaléna - Bobáľ, Pavel - Kauerová, Tereza PY - 2022 TI - Novel potential histone deacetylase inhibitors and their proapoptotic effects in cancer cells SN - 9788028001063 KW - histone deacetylase inhibitors KW - vorinostat KW - hydroxamic acids KW - histones KW - apoptosis UR - https://www.pharm.muni.cz/veda-a-vyzkum/svk/magistersti-studenti/archiv-sborniku/2022 N2 - Our research studied the biological activity of new derivates of hydroxamic acids as potential histone deacetylase inhibitors designed and synthesized by the Department of Chemical Drugs, Faculty of Pharmacy, Masaryk University. In particular, our study was focused on evaluating their potential to affect histone acetylation and to induce apoptosis in the monocytic leukemia cell line compared with vorinostat. ER -
DVOŘÁKOVÁ, Martina, Peter KOLLÁR, Magdaléna ONUŠČÁKOVÁ, Pavel BOBÁĽ and Tereza KAUEROVÁ. Novel potential histone deacetylase inhibitors and their proapoptotic effects in cancer cells. In \textit{Student Scientific Conference MUNI PHARM 2022}. 2022. ISBN~978-80-280-0106-3.
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