J 2023

Role of the Inspiratory Muscles on Functional Performance From Critical Care to Hospital Discharge and Beyond in Patients With COVID-19

FORMIGA, Magno F, Filip DOSBABA, Martin HARTMAN, Ladislav BAŤALÍK, Vojtech SENKYR et. al.

Basic information

Original name

Role of the Inspiratory Muscles on Functional Performance From Critical Care to Hospital Discharge and Beyond in Patients With COVID-19

Authors

FORMIGA, Magno F, Filip DOSBABA (203 Czech Republic), Martin HARTMAN (203 Czech Republic), Ladislav BAŤALÍK (203 Czech Republic, belonging to the institution), Vojtech SENKYR (203 Czech Republic), Ivana RADKOVCOVA (203 Czech Republic), Svatopluk RICHTER (203 Czech Republic), Kristián BRAT (703 Slovakia) and Lawrence P CAHALIN

Edition

PHYSICAL THERAPY, CARY, OXFORD UNIV PRESS INC, 2023, 0031-9023

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.200 in 2022

RIV identification code

RIV/00216224:14110/23:00131759

Organization unit

Faculty of Medicine

DOI

UT WoS

001042704600001

Keywords in English

1 Minute Sit-to-Stand Test; COVID-19; Function; Functional Performance; Inspiratory Muscle Performance; Maximal Inspiratory Pressure

Tags

Tags

International impact, Reviewed
Změněno: 29/1/2024 14:22, Mgr. Tereza Miškechová

Abstract

V originále

Objective The role of inspiratory muscle performance in functional performance in patients with coronavirus disease 2019 (COVID-19) is poorly understood. The purpose of this study was to perform a longitudinal examination of inspiratory and functional performance from intensive care unit (ICU) discharge (ICUD) to hospital discharge (HD) and symptoms at HD and 1 month after HD in patients with COVID-19. Methods Thirty patients (19 men, 11 women) with COVID-19 were included. Examination of inspiratory muscle performance at ICUD and HD was performed with an electronic manometer, which provided the maximal inspiratory pressure (MIP) and several other inspiratory measures. Examination of dyspnea and functional performance was performed at ICUD and HD with the Modified Borg Dyspnea Scale and the 1-minute sit-to-stand test (1MSST), respectively. Results The mean age was 71 (SD = 11) years, the mean length of ICU stay was 9 (SD = 6) days, and the mean length of hospital stay was 26 (SD = 16) days. Most of the patients were diagnosed with severe COVID-19 (76.7%) and had a mean Charlson Comorbidity Index of 4.4 (SD = 1.9), reflecting high comorbidity. The mean MIP of the entire cohort increased minimally from ICUD to HD (from 36 [SD = 21] to 40 [SD = 20] cm H2O), reflecting predicted values for men and women at ICUD and HD of 46 (25%) to 51 (23%) and 37 (24%) to 37 (20%), respectively. The 1MSTS score increased significantly from ICUD to HD (9.9 [SD = 7.1] vs 17.7 [SD = 11.1]) for the entire cohort but remained far below population-based reference values (2.5th percentile) for the majority of patients at ICUD and HD. At ICUD, MIP was found to be a significant predictor of a favorable change in 1MSTS performance (& beta; = 0.308; odds ratio = 1.36) at HD. Conclusion A significant reduction in inspiratory and functional performance exists in patients with COVID-19 at both ICUD and HD, with a greater MIP at ICUD being a significant predictor of a greater 1MSTS score at HD. Impact This study shows that inspiratory muscle training may be an important adjunct after COVID-19.