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@article{2319477,
author = {Brat, Kristián and Chovanec, Zdeněk and Mitáš, Ladislav and Šrámek, Vladimír and Olson, Lyle J and Čundrle, Ivan},
article_location = {CAMBRIDGE},
article_number = {6},
doi = {http://dx.doi.org/10.1016/j.heliyon.2023.e17606},
keywords = {Hyperoxemia; Lung resection surgery; Post-operative complications},
language = {eng},
issn = {2405-8440},
journal = {Heliyon},
title = {Hyperoxemia post thoracic surgery-Does it matter?},
url = {https://linkinghub.elsevier.com/retrieve/pii/S2405844023048144},
volume = {9},
year = {2023}
}
TY - JOUR
ID - 2319477
AU - Brat, Kristián - Chovanec, Zdeněk - Mitáš, Ladislav - Šrámek, Vladimír - Olson, Lyle J - Čundrle, Ivan
PY - 2023
TI - Hyperoxemia post thoracic surgery-Does it matter?
JF - Heliyon
VL - 9
IS - 6
SP - 1-8
EP - 1-8
PB - Elsevier
SN - 24058440
KW - Hyperoxemia
KW - Lung resection surgery
KW - Post-operative complications
UR - https://linkinghub.elsevier.com/retrieve/pii/S2405844023048144
N2 - Introduction: Post-operative oxygen therapy is used to prevent hypoxemia and surgical site infection. However, with improvements of anesthesia techniques, post-operative hypoxemia incidence is declining and the benefits of oxygen on surgical site infection have been questioned. Moreover, hyperoxemia might have adverse effects on the pulmonary and cardiovascular systems. We hypothesized hyperoxemia post thoracic surgery is associated with post-operative pulmonary and cardiovascular complications.Methods: Consecutive lung resection patients were included in this post-hoc analysis. Postoperative pulmonary and cardiovascular complications were prospectively assessed during the first 30 post-operative days, or hospital stay. Arterial blood gases were analyzed at 1, 6 and 12 h after surgery. Hyperoxemia was defined as arterial partial pressure of oxygen (PaO2)>100 mmHg. Patients with hyperoxemia duration in at least two adjacent time points were considered as hyperoxemic. Student t-test, Mann-Whitney U test and two-tailed Fisher exact test were used for group comparison. P values < 0.05 were considered statistically significant.Results: Three hundred sixty-three consecutive patients were included in this post-hoc analysis. Two hundred five patients (57%), were considered hyperoxemic and included in the hyperoxemia group. Patients in the hyperoxemia group had significantly higher PaO2 at 1, 6 and 12 h after surgery (p < 0.05). Otherwise, there was no significant difference in age, sex, comorbidities, pulmonary function tests parameters, lung surgery procedure, incidence of post-operative pulmonary and cardiovascular complications, intensive care unit and hospital length of stay and 30 day mortality.Conclusion: Hyperoxemia after lung resection surgery is common and not associated with postoperative complications or 30-day mortality.
ER -
BRAT, Kristián, Zdeněk CHOVANEC, Ladislav MITÁŠ, Vladimír ŠRÁMEK, Lyle J OLSON and Ivan ČUNDRLE. Hyperoxemia post thoracic surgery-Does it matter? \textit{Heliyon}. CAMBRIDGE: Elsevier, 2023, vol.~9, No~6, p.~1-8. ISSN~2405-8440. Available from: https://dx.doi.org/10.1016/j.heliyon.2023.e17606.
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