Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events A 1-Year Follow-up
Authors
NGUYEN, Thanh N (guarantor), Muhammad M QURESHI, Piers KLEIN, Hiroshi YAMAGAMI, Robert MIKULÍK (203 Czech Republic, belonging to the institution), Anna CZLONKOWSKA, Mohamad ABDALKADER, Petra ŠEDOVÁ (203 Czech Republic, belonging to the institution), Anvitha SATHYA, Hannah C LO, Ossama Yassin MANSOUR, Husitha Reddy VANGURU, Emilie LESAINE, Georgios TSIVGOULIS, Aaron I LOOCHTAN, Jelle DEMEESTERE, Ken UCHINO, Violiza INOA, Nitin GOYAL, Andreas CHARIDIMOU, James E SIEGLER, Shadi YAGHI, de Sousa Diana AGUIAR, Mahmoud H MOHAMMADEN, Diogo C HAUSSEN, Espen Saxhaug KRISTOFFERSEN, Virginia Pujol LEREIS, Sergio Daniel SCOLLO, Bruce C V CAMPBELL, Alice MA, James Orton THOMAS, Mark W PARSONS, Shaloo SINGHAL, Lee-Anne SLATER, Rodrigo Tomazini MARTINS, Chris ENZINGER, Thomas GATTRINGER, Aminur RAHMAN, Thomas BONNET, Noemie LIGOT, De Raedt SYLVIE, Robin LEMMENS, Peter VANACKER, Fenne VANDERVORST, Adriana Bastos CONFORTO, Raquel C T HIDALGO, Luciana de Oliveira NEVES, Rodrigo Targa MARTINS, Mora Cuervo Daissy LILIANA, Leticia C REBELLO, Igor Bessa SANTIAGO, da Silva Isabelle LAMEIRINHAS, Teodora SAKELAROVA, Rosen KALPACHKI, Filip ALEXIEV, Luciana CATANESE, Elena Adela CORA, Mayank GOYAL, Michael D HILL, Michael E KELLY, Houman KHOSRAVANI, Pascale LAVOIE, Lissa PEELING, Aleksandra PIKULA, Rodrigo RIVERA, Hui-Sheng CHEN, Yimin CHEN, Xiaochuan HUO, Zhongrong MIAO, Shuiquan YANG, Marina Roje BEDEKOVIC, Marina BRALIC, Hrvoje BUDINCEVIC, Angel Basilio CORREDOR-QUINTERO, Osvaldo E LARA-SARABIA, Martin CABAL, Dusan TENORA, Petr FIBRICH, Roman HERZIG, Emanuela HRABANOVSKA, David HLINOVSKY, Lubomir JURAK, Jana KADLCIKOVA, Igor KARPOWICZ, Lukas KLECKA, Martin KOVAR, David LAUER, Jiri NEUMANN, Hana PALOUSKOVA, Martin REISER, Petra REKOVA, Vladimir ROHAN, Ondrej SKODA, Miroslav ŠKORŇA (203 Czech Republic, belonging to the institution), Martin SRAMEK, Lenka ZAKOVA, Hanne CHRISTENSEN, Nicolas DRENCK, Helle Klingenberg IVERSEN, Thomas Clement TRUELSEN, Troels WIENECKE, Khalid SOBH, Pauli YLIKOTILA, Kemal ALPAY, Daniel STRBIAN, Patricia BERNADY, Philippe CASENAVE, Maria DAN, Jean-Marc FAUCHEUX, Jean-Christophe GENTRIC, Elsa MAGRO, Candice SABBEN, Peggy REINER, Francois ROUANET, Ferdinand O BOHMANN, Stefan BOSKAMP, Joshua MBROH, Simon NAGEL, Christian H NOLTE, Peter A RINGLEB, Michael ROSENKRANZ, Sven POLI, Gotz THOMALLA, Theodoros KARAPANAYIOTIDES, Ioanna KOUTROULOU, Odysseas KARGIOTIS, Lina PALAIODIMOU, Barrientos Guerra Jose DOMINGUO, Vikram HUDED, Bindu MENON, Shashank NAGENDRA, Chintan PRAJAPATI, P N SYLAJA, Nyoman Angga Krishna PRAMANA, Achmad Firdaus SANI, Abdoreza GHOREISHI, Mehdi FARHOUDI, Elyar Sadeghi HOKMABADI, Abu Raya TARIQ, Shani Avnery KALMANOVICH, Levite RONEN, Sergiu Ionut SABETAY, Maurizio ACAMPA, Alessandro ADAMI, Lucio CASTELLAN, Marco LONGONI, Raffaele ORNELLO, Leonardo RENIERI, Claudia Rolla BIGLIANI, Michele ROMOLI, Simona SACCO, Andrea SALMAGGI, Davide SANGALLI, Andrea ZINI, Ryosuke DOIJIRI, Hiroki FUKUDA, Toshiyuki FUJINAKA, Kyohei FUJITA, Hirotoshi IMAMURA, Nobuyuki SAKAI, Takuya KANAMARU, Naoto KIMURA, Ryuhei KONO, Kosuke MIYAKE, Manabu SAKAGUCHI, Kenichiro SAKAI, Kazutaka SONODA, Kenichi TODO, Fumio MIYASHITA, Naoki TOKUDA, Yuji MATSUMARU, Shoji MATSUMOTO, Nobuyuki OHARA, Seigo SHINDO, Yohei TAKENOBU, Takeshi YOSHIMOTO, Kazunori TOYODA, Takeshi UWATOKO, Yoshiki YAGITA, Takehiro YAMADA, Nobuaki YAMAMOTO, Ryoo YAMAMOTO, Yukako YAZAWA, Yuri SUGIURA, Peter Kuria WAWERU, Jang-Hyun BAEK, Si Baek LEE, Kwon-Duk SEO, Sung-Il SOHN, Anita Ante ARSOVSKA, Yong Chieh CHAN, Wan Asyraf Wan ZAIDI, Ainul Syahrilfazli JAAFAR, Fernando GONGORA-RIVERA, Manuel MARTINEZ-MARINO, Adrian INFANTE-VALENZUELA, Stanislav GROPPA, Pavel LEAHU, Jonathan M COUTINHO, Leon A RINKEL, Diederik W J DIPPEL, Dianne H K VAN DAM-NOLEN, Annemarei RANTA, Teddy Y WU, Tajudeen Temitayo ADEBAYO, Abiodun H BELLO, Ernest Okwundu NWAZOR, Taofiki Ajao SUNMONU, Kolawole Wasiu WAHAB, Ole Morten RONNING, Else Charlotte SANDSET, Amal M AL HASHMI, Saima AHMAD, Umair RASHID, Liliana RODRIGUEZ-KADOTA, Patrick Matic YALUNG, Jon Stewart Hao DY, Maria Carissa PINEDA-FRANKS, Christian Oliver CO, Waldemar BROLA, Aleksander DEBIEC, Malgorzata DOROBEK, Michal Adam KARLINSKI, Beata M LABUZ-ROSZAK, Anetta LASEK-BAL, Halina SIENKIEWICZ-JAROSZ, Jacek STASZEWSKI, Piotr SOBOLEWSKI, Marcin WIACEK, Justyna ZIELINSKA-TUREK, Andre Pinho ARAUJO, Mariana ROCHA, Pedro CASTRO, Vitor Tedim CRUZ, Paulo Venancio FERREIRA, Patricia FERREIRA, Ana Paiva NUNES, Luisa FONSECA, Joao Pedro MARTO, Pinho e Melo TERESA, Miguel RODRIGUES, M Luis SILVA, Adela DIMITRIADE, Cristian FALUP-PECURARIU, May Adel HAMID, Narayanaswamy VENKETASUBRAMANIAN, Georgi KRASTEV, Miroslav MAKO, Oscar AYO-MARTIN, Francisco HERNANDEZ-FERANDEZ, Jordi BLASCO, Alejandro RODRIGUEZ-VAZQUEZ, Antonio CRUZ-CULEBRAS, Francisco MONICHE, Joan MONTANER, Soledad PEREZ-SANCHEZ, Garcia Sanchez Maria JESAS, Guillan Rodriguez MARTA, Katarina JOOD, Annika NORDANSTIG, Michael V MAZYA, Tiago T P MOREIRA, Gianmarco BERNAVA, Morin BEYELER, Manuel BOLOGNESE, Emmanuel CARRERA, Tomas DOBROCKY, Grzegorz Marek KARWACKI, Emanuela KELLER, Chang Yang HSIEH, Surawan BOONYAKARNKUL, Anchalee CHUROJANA, Ozlem AYKAC, Atilla Azcan OZDEMIR, Arsida BAJRAMI, Songul SENADIM, Syed Irteza HUSSAIN, Seby JOHN, Soma BANERJEE, Joseph KWAN, Kailash KRISHNAN, Robert LENTHALL, Ashok MATTHEWS, Ken WONG, Liqun ZHANG, Dorothea ALTSCHUL, Kaiz S ASIF, Zeelalem BAHIRU, Kristine BELOW, Sean RULAND, Saqib A CHAUDRY, Michael CHEN, Alex CHEBL, Jackie CIBULKA, Leon CISTRUNK, Judith CLARK, Marco COLASURDO, Alexandra CZAP, de Havenon ADAM, Salvatore AMATO, Sushrut DHARMADHIKARI, Kasey B GRIMMETT, Adam A DMYTRIW, Mark R ETHERTON, Chizoba EZEPUE, Mudassir FAROOQUI, Steven K FESKE, Lauren FINK, Ulviyya GASIMOVA, Amy K GUZIK, Maryam HAKEMI, Majesta HOVINGH, Muhib KHAN, Dinesh JILLELA, Rakesh KHATRI, Ayaz M KHAWAJA, Naim N KHOURY, Nicole L KILEY, Benny S KIM, Murali K KOLIKONDA, Anna Luisa KUHN, Stephanie LARA, Guillermo LINARES, Italo LINFANTE, Timothy G LUKOVITS, Sarah LYCAN, Shailesh S MALE, Laith MAALI, John MANCIN, Hesham MASOUD, Ghada A MOHAMED, Andre MONTEIRO, Fadi NAHAB, Krishna NALLEBALLE, Santiago ORTEGA-GUTIERREZ, Ajit S PURI, Yazan RADAIDEH, Rahul H RAHANGDALE, Ansaar RAI, Pankajavalli RAMAKRISHNAN, Aravind B REDDY, Diana M ROJAS-SOTO, Jose Rafael ROMERO, Natalia S ROST, Aaron ROTHSTEIN, Setareh Salehi OMRAN, Sunil A SHETH, Adnan H SIDDIQUI, Amy K STAROSCIAK, Nicholas E TARLOV, Robert A TAYLOR, Michael J WANG, Jared WOLFE, Ka-Ho WONG, Huynh Vu LE, Quy Viet NGUYEN, Thong Nhu PHAM, Trung Thanh NGUYEN, Hoang Thi PHAN, Mai Duy TON, Urs FISCHER, Patrik MICHEL, Davide STRAMBO, Sheila O MARTINS, Osama O ZAIDAT and Raul G NOGUEIRA
Edition
Neurology, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2023, 0028-3878
Background and Objectives Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020). Methods We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1–6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1–4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4–5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6–0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31–1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82–2.97], 5,656/195,539) of all stroke hospitalizations. Discussion There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.
NGUYEN, Thanh N, Muhammad M QURESHI, Piers KLEIN, Hiroshi YAMAGAMI, Robert MIKULÍK, Anna CZLONKOWSKA, Mohamad ABDALKADER, Petra ŠEDOVÁ, Anvitha SATHYA, Hannah C LO, Ossama Yassin MANSOUR, Husitha Reddy VANGURU, Emilie LESAINE, Georgios TSIVGOULIS, Aaron I LOOCHTAN, Jelle DEMEESTERE, Ken UCHINO, Violiza INOA, Nitin GOYAL, Andreas CHARIDIMOU, James E SIEGLER, Shadi YAGHI, de Sousa Diana AGUIAR, Mahmoud H MOHAMMADEN, Diogo C HAUSSEN, Espen Saxhaug KRISTOFFERSEN, Virginia Pujol LEREIS, Sergio Daniel SCOLLO, Bruce C V CAMPBELL, Alice MA, James Orton THOMAS, Mark W PARSONS, Shaloo SINGHAL, Lee-Anne SLATER, Rodrigo Tomazini MARTINS, Chris ENZINGER, Thomas GATTRINGER, Aminur RAHMAN, Thomas BONNET, Noemie LIGOT, De Raedt SYLVIE, Robin LEMMENS, Peter VANACKER, Fenne VANDERVORST, Adriana Bastos CONFORTO, Raquel C T HIDALGO, Luciana de Oliveira NEVES, Rodrigo Targa MARTINS, Mora Cuervo Daissy LILIANA, Leticia C REBELLO, Igor Bessa SANTIAGO, da Silva Isabelle LAMEIRINHAS, Teodora SAKELAROVA, Rosen KALPACHKI, Filip ALEXIEV, Luciana CATANESE, Elena Adela CORA, Mayank GOYAL, Michael D HILL, Michael E KELLY, Houman KHOSRAVANI, Pascale LAVOIE, Lissa PEELING, Aleksandra PIKULA, Rodrigo RIVERA, Hui-Sheng CHEN, Yimin CHEN, Xiaochuan HUO, Zhongrong MIAO, Shuiquan YANG, Marina Roje BEDEKOVIC, Marina BRALIC, Hrvoje BUDINCEVIC, Angel Basilio CORREDOR-QUINTERO, Osvaldo E LARA-SARABIA, Martin CABAL, Dusan TENORA, Petr FIBRICH, Roman HERZIG, Emanuela HRABANOVSKA, David HLINOVSKY, Lubomir JURAK, Jana KADLCIKOVA, Igor KARPOWICZ, Lukas KLECKA, Martin KOVAR, David LAUER, Jiri NEUMANN, Hana PALOUSKOVA, Martin REISER, Petra REKOVA, Vladimir ROHAN, Ondrej SKODA, Miroslav ŠKORŇA, Martin SRAMEK, Lenka ZAKOVA, Hanne CHRISTENSEN, Nicolas DRENCK, Helle Klingenberg IVERSEN, Thomas Clement TRUELSEN, Troels WIENECKE, Khalid SOBH, Pauli YLIKOTILA, Kemal ALPAY, Daniel STRBIAN, Patricia BERNADY, Philippe CASENAVE, Maria DAN, Jean-Marc FAUCHEUX, Jean-Christophe GENTRIC, Elsa MAGRO, Candice SABBEN, Peggy REINER, Francois ROUANET, Ferdinand O BOHMANN, Stefan BOSKAMP, Joshua MBROH, Simon NAGEL, Christian H NOLTE, Peter A RINGLEB, Michael ROSENKRANZ, Sven POLI, Gotz THOMALLA, Theodoros KARAPANAYIOTIDES, Ioanna KOUTROULOU, Odysseas KARGIOTIS, Lina PALAIODIMOU, Barrientos Guerra Jose DOMINGUO, Vikram HUDED, Bindu MENON, Shashank NAGENDRA, Chintan PRAJAPATI, P N SYLAJA, Nyoman Angga Krishna PRAMANA, Achmad Firdaus SANI, Abdoreza GHOREISHI, Mehdi FARHOUDI, Elyar Sadeghi HOKMABADI, Abu Raya TARIQ, Shani Avnery KALMANOVICH, Levite RONEN, Sergiu Ionut SABETAY, Maurizio ACAMPA, Alessandro ADAMI, Lucio CASTELLAN, Marco LONGONI, Raffaele ORNELLO, Leonardo RENIERI, Claudia Rolla BIGLIANI, Michele ROMOLI, Simona SACCO, Andrea SALMAGGI, Davide SANGALLI, Andrea ZINI, Ryosuke DOIJIRI, Hiroki FUKUDA, Toshiyuki FUJINAKA, Kyohei FUJITA, Hirotoshi IMAMURA, Nobuyuki SAKAI, Takuya KANAMARU, Naoto KIMURA, Ryuhei KONO, Kosuke MIYAKE, Manabu SAKAGUCHI, Kenichiro SAKAI, Kazutaka SONODA, Kenichi TODO, Fumio MIYASHITA, Naoki TOKUDA, Yuji MATSUMARU, Shoji MATSUMOTO, Nobuyuki OHARA, Seigo SHINDO, Yohei TAKENOBU, Takeshi YOSHIMOTO, Kazunori TOYODA, Takeshi UWATOKO, Yoshiki YAGITA, Takehiro YAMADA, Nobuaki YAMAMOTO, Ryoo YAMAMOTO, Yukako YAZAWA, Yuri SUGIURA, Peter Kuria WAWERU, Jang-Hyun BAEK, Si Baek LEE, Kwon-Duk SEO, Sung-Il SOHN, Anita Ante ARSOVSKA, Yong Chieh CHAN, Wan Asyraf Wan ZAIDI, Ainul Syahrilfazli JAAFAR, Fernando GONGORA-RIVERA, Manuel MARTINEZ-MARINO, Adrian INFANTE-VALENZUELA, Stanislav GROPPA, Pavel LEAHU, Jonathan M COUTINHO, Leon A RINKEL, Diederik W J DIPPEL, Dianne H K VAN DAM-NOLEN, Annemarei RANTA, Teddy Y WU, Tajudeen Temitayo ADEBAYO, Abiodun H BELLO, Ernest Okwundu NWAZOR, Taofiki Ajao SUNMONU, Kolawole Wasiu WAHAB, Ole Morten RONNING, Else Charlotte SANDSET, Amal M AL HASHMI, Saima AHMAD, Umair RASHID, Liliana RODRIGUEZ-KADOTA, Patrick Matic YALUNG, Jon Stewart Hao DY, Maria Carissa PINEDA-FRANKS, Christian Oliver CO, Waldemar BROLA, Aleksander DEBIEC, Malgorzata DOROBEK, Michal Adam KARLINSKI, Beata M LABUZ-ROSZAK, Anetta LASEK-BAL, Halina SIENKIEWICZ-JAROSZ, Jacek STASZEWSKI, Piotr SOBOLEWSKI, Marcin WIACEK, Justyna ZIELINSKA-TUREK, Andre Pinho ARAUJO, Mariana ROCHA, Pedro CASTRO, Vitor Tedim CRUZ, Paulo Venancio FERREIRA, Patricia FERREIRA, Ana Paiva NUNES, Luisa FONSECA, Joao Pedro MARTO, Pinho e Melo TERESA, Miguel RODRIGUES, M Luis SILVA, Adela DIMITRIADE, Cristian FALUP-PECURARIU, May Adel HAMID, Narayanaswamy VENKETASUBRAMANIAN, Georgi KRASTEV, Miroslav MAKO, Oscar AYO-MARTIN, Francisco HERNANDEZ-FERANDEZ, Jordi BLASCO, Alejandro RODRIGUEZ-VAZQUEZ, Antonio CRUZ-CULEBRAS, Francisco MONICHE, Joan MONTANER, Soledad PEREZ-SANCHEZ, Garcia Sanchez Maria JESAS, Guillan Rodriguez MARTA, Katarina JOOD, Annika NORDANSTIG, Michael V MAZYA, Tiago T P MOREIRA, Gianmarco BERNAVA, Morin BEYELER, Manuel BOLOGNESE, Emmanuel CARRERA, Tomas DOBROCKY, Grzegorz Marek KARWACKI, Emanuela KELLER, Chang Yang HSIEH, Surawan BOONYAKARNKUL, Anchalee CHUROJANA, Ozlem AYKAC, Atilla Azcan OZDEMIR, Arsida BAJRAMI, Songul SENADIM, Syed Irteza HUSSAIN, Seby JOHN, Soma BANERJEE, Joseph KWAN, Kailash KRISHNAN, Robert LENTHALL, Ashok MATTHEWS, Ken WONG, Liqun ZHANG, Dorothea ALTSCHUL, Kaiz S ASIF, Zeelalem BAHIRU, Kristine BELOW, Sean RULAND, Saqib A CHAUDRY, Michael CHEN, Alex CHEBL, Jackie CIBULKA, Leon CISTRUNK, Judith CLARK, Marco COLASURDO, Alexandra CZAP, de Havenon ADAM, Salvatore AMATO, Sushrut DHARMADHIKARI, Kasey B GRIMMETT, Adam A DMYTRIW, Mark R ETHERTON, Chizoba EZEPUE, Mudassir FAROOQUI, Steven K FESKE, Lauren FINK, Ulviyya GASIMOVA, Amy K GUZIK, Maryam HAKEMI, Majesta HOVINGH, Muhib KHAN, Dinesh JILLELA, Rakesh KHATRI, Ayaz M KHAWAJA, Naim N KHOURY, Nicole L KILEY, Benny S KIM, Murali K KOLIKONDA, Anna Luisa KUHN, Stephanie LARA, Guillermo LINARES, Italo LINFANTE, Timothy G LUKOVITS, Sarah LYCAN, Shailesh S MALE, Laith MAALI, John MANCIN, Hesham MASOUD, Ghada A MOHAMED, Andre MONTEIRO, Fadi NAHAB, Krishna NALLEBALLE, Santiago ORTEGA-GUTIERREZ, Ajit S PURI, Yazan RADAIDEH, Rahul H RAHANGDALE, Ansaar RAI, Pankajavalli RAMAKRISHNAN, Aravind B REDDY, Diana M ROJAS-SOTO, Jose Rafael ROMERO, Natalia S ROST, Aaron ROTHSTEIN, Setareh Salehi OMRAN, Sunil A SHETH, Adnan H SIDDIQUI, Amy K STAROSCIAK, Nicholas E TARLOV, Robert A TAYLOR, Michael J WANG, Jared WOLFE, Ka-Ho WONG, Huynh Vu LE, Quy Viet NGUYEN, Thong Nhu PHAM, Trung Thanh NGUYEN, Hoang Thi PHAN, Mai Duy TON, Urs FISCHER, Patrik MICHEL, Davide STRAMBO, Sheila O MARTINS, Osama O ZAIDAT and Raul G NOGUEIRA. Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events A 1-Year Follow-up. Neurology. Philadelphia: LIPPINCOTT WILLIAMS & WILKINS, 2023, vol. 100, No 4, p. "E408"-"E421", 14 pp. ISSN 0028-3878. Available from: https://dx.doi.org/10.1212/WNL.0000000000201426.
@article{2319538, author = {Nguyen, Thanh N and Qureshi, Muhammad M and Klein, Piers and Yamagami, Hiroshi and Mikulík, Robert and Czlonkowska, Anna and Abdalkader, Mohamad and Šedová, Petra and Sathya, Anvitha and Lo, Hannah C and Mansour, Ossama Yassin and Vanguru, Husitha Reddy and Lesaine, Emilie and Tsivgoulis, Georgios and Loochtan, Aaron I and Demeestere, Jelle and Uchino, Ken and Inoa, Violiza and Goyal, Nitin and Charidimou, Andreas and Siegler, James E and Yaghi, Shadi and Aguiar, de Sousa Diana and Mohammaden, Mahmoud H and Haussen, Diogo C and Kristoffersen, Espen Saxhaug and Lereis, Virginia Pujol and Scollo, Sergio Daniel and Campbell, Bruce C V and Ma, Alice and Thomas, James Orton and Parsons, Mark W and Singhal, Shaloo and Slater, LeeandAnne and Martins, Rodrigo Tomazini and Enzinger, Chris and Gattringer, Thomas and Rahman, Aminur and Bonnet, Thomas and Ligot, Noemie and Sylvie, De Raedt and Lemmens, Robin and Vanacker, Peter and Vandervorst, Fenne and Conforto, Adriana Bastos and Hidalgo, Raquel C T and Neves, Luciana de Oliveira and Martins, Rodrigo Targa and Liliana, Mora Cuervo Daissy and Rebello, Leticia C and Santiago, Igor Bessa and Lameirinhas, da Silva Isabelle and Sakelarova, Teodora and Kalpachki, Rosen and Alexiev, Filip and Catanese, Luciana and Cora, Elena Adela and Goyal, Mayank and Hill, Michael D and Kelly, Michael E and Khosravani, Houman and Lavoie, Pascale and Peeling, Lissa and Pikula, Aleksandra and Rivera, Rodrigo and Chen, HuiandSheng and Chen, Yimin and Huo, Xiaochuan and Miao, Zhongrong and Yang, Shuiquan and Bedekovic, Marina Roje and Bralic, Marina and Budincevic, Hrvoje and CorredorandQuintero, Angel Basilio and LaraandSarabia, Osvaldo E and Cabal, Martin and Tenora, Dusan and Fibrich, Petr and Herzig, Roman and Hrabanovska, Emanuela and Hlinovsky, David and Jurak, Lubomir and Kadlcikova, Jana and Karpowicz, Igor and Klecka, Lukas and Kovar, Martin and Lauer, David and Neumann, Jiri and Palouskova, Hana and Reiser, Martin and Rekova, Petra and Rohan, Vladimir and Skoda, Ondrej and Škorňa, Miroslav and Sramek, Martin and Zakova, Lenka and Christensen, Hanne and Drenck, Nicolas and Iversen, Helle Klingenberg and Truelsen, Thomas Clement and Wienecke, Troels and Sobh, Khalid and Ylikotila, Pauli and Alpay, Kemal and Strbian, Daniel and Bernady, Patricia and Casenave, Philippe and Dan, Maria and Faucheux, JeanandMarc and Gentric, JeanandChristophe and Magro, Elsa and Sabben, Candice and Reiner, Peggy and Rouanet, Francois and Bohmann, Ferdinand O and Boskamp, Stefan and Mbroh, Joshua and Nagel, Simon and Nolte, Christian H and Ringleb, Peter A and Rosenkranz, Michael and Poli, Sven and Thomalla, Gotz and Karapanayiotides, Theodoros and Koutroulou, Ioanna and Kargiotis, Odysseas and Palaiodimou, Lina and Dominguo, Barrientos Guerra Jose and Huded, Vikram and Menon, Bindu and Nagendra, Shashank and Prajapati, Chintan and Sylaja, P N and Pramana, Nyoman Angga Krishna and Sani, Achmad Firdaus and Ghoreishi, Abdoreza and Farhoudi, Mehdi and Hokmabadi, Elyar Sadeghi and Tariq, Abu Raya and Kalmanovich, Shani Avnery and Ronen, Levite and Sabetay, Sergiu Ionut and Acampa, Maurizio and Adami, Alessandro and Castellan, Lucio and Longoni, Marco and Ornello, Raffaele and Renieri, Leonardo and Bigliani, Claudia Rolla and Romoli, Michele and Sacco, Simona and Salmaggi, Andrea and Sangalli, Davide and Zini, Andrea and Doijiri, Ryosuke and Fukuda, Hiroki and Fujinaka, Toshiyuki and Fujita, Kyohei and Imamura, Hirotoshi and Sakai, Nobuyuki and Kanamaru, Takuya and Kimura, Naoto and Kono, Ryuhei and Miyake, Kosuke and Sakaguchi, Manabu and Sakai, Kenichiro and Sonoda, Kazutaka and Todo, Kenichi and Miyashita, Fumio and Tokuda, Naoki and Matsumaru, Yuji and Matsumoto, Shoji and Ohara, Nobuyuki and Shindo, Seigo and Takenobu, Yohei and Yoshimoto, Takeshi and Toyoda, Kazunori and Uwatoko, Takeshi and Yagita, Yoshiki et al.}, article_location = {Philadelphia}, article_number = {4}, doi = {http://dx.doi.org/10.1212/WNL.0000000000201426}, keywords = {COVID-19 Pandemic; Stroke Volumes; Cerebrovascular Events}, language = {eng}, issn = {0028-3878}, journal = {Neurology}, title = {Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events A 1-Year Follow-up}, url = {https://n.neurology.org/content/100/4/e408}, volume = {100}, year = {2023} }
TY - JOUR ID - 2319538 AU - Nguyen, Thanh N - Qureshi, Muhammad M - Klein, Piers - Yamagami, Hiroshi - Mikulík, Robert - Czlonkowska, Anna - Abdalkader, Mohamad - Šedová, Petra - Sathya, Anvitha - Lo, Hannah C - Mansour, Ossama Yassin - Vanguru, Husitha Reddy - Lesaine, Emilie - Tsivgoulis, Georgios - Loochtan, Aaron I - Demeestere, Jelle - Uchino, Ken - Inoa, Violiza - Goyal, Nitin - Charidimou, Andreas - Siegler, James E - Yaghi, Shadi - Aguiar, de Sousa Diana - Mohammaden, Mahmoud H - Haussen, Diogo C - Kristoffersen, Espen Saxhaug - Lereis, Virginia Pujol - Scollo, Sergio Daniel - Campbell, Bruce C V - Ma, Alice - Thomas, James Orton - Parsons, Mark W - Singhal, Shaloo - Slater, Lee-Anne - Martins, Rodrigo Tomazini - Enzinger, Chris - Gattringer, Thomas - Rahman, Aminur - Bonnet, Thomas - Ligot, Noemie - Sylvie, De Raedt - Lemmens, Robin - Vanacker, Peter - Vandervorst, Fenne - Conforto, Adriana Bastos - Hidalgo, Raquel C T - Neves, Luciana de Oliveira - Martins, Rodrigo Targa - Liliana, Mora Cuervo Daissy - Rebello, Leticia C - Santiago, Igor Bessa - Lameirinhas, da Silva Isabelle - Sakelarova, Teodora - Kalpachki, Rosen - Alexiev, Filip - Catanese, Luciana - Cora, Elena Adela - Goyal, Mayank - Hill, Michael D - Kelly, Michael E - Khosravani, Houman - Lavoie, Pascale - Peeling, Lissa - Pikula, Aleksandra - Rivera, Rodrigo - Chen, Hui-Sheng - Chen, Yimin - Huo, Xiaochuan - Miao, Zhongrong - Yang, Shuiquan - Bedekovic, Marina Roje - Bralic, Marina - Budincevic, Hrvoje - Corredor-Quintero, Angel Basilio - Lara-Sarabia, Osvaldo E - Cabal, Martin - Tenora, Dusan - Fibrich, Petr - Herzig, Roman - Hrabanovska, Emanuela - Hlinovsky, David - Jurak, Lubomir - Kadlcikova, Jana - Karpowicz, Igor - Klecka, Lukas - Kovar, Martin - Lauer, David - Neumann, Jiri - Palouskova, Hana - Reiser, Martin - Rekova, Petra - Rohan, Vladimir - Skoda, Ondrej - Škorňa, Miroslav - Sramek, Martin - Zakova, Lenka - Christensen, Hanne - Drenck, Nicolas - Iversen, Helle Klingenberg - Truelsen, Thomas Clement - Wienecke, Troels - Sobh, Khalid - Ylikotila, Pauli - Alpay, Kemal - Strbian, Daniel - Bernady, Patricia - Casenave, Philippe - Dan, Maria - Faucheux, Jean-Marc - Gentric, Jean-Christophe - Magro, Elsa - Sabben, Candice - Reiner, Peggy - Rouanet, Francois - Bohmann, Ferdinand O - Boskamp, Stefan - Mbroh, Joshua - Nagel, Simon - Nolte, Christian H - Ringleb, Peter A - Rosenkranz, Michael - Poli, Sven - Thomalla, Gotz - Karapanayiotides, Theodoros - Koutroulou, Ioanna - Kargiotis, Odysseas - Palaiodimou, Lina - Dominguo, Barrientos Guerra Jose - Huded, Vikram - Menon, Bindu - Nagendra, Shashank - Prajapati, Chintan - Sylaja, P N - Pramana, Nyoman Angga Krishna - Sani, Achmad Firdaus - Ghoreishi, Abdoreza - Farhoudi, Mehdi - Hokmabadi, Elyar Sadeghi - Tariq, Abu Raya - Kalmanovich, Shani Avnery - Ronen, Levite - Sabetay, Sergiu Ionut - Acampa, Maurizio - Adami, Alessandro - Castellan, Lucio - Longoni, Marco - Ornello, Raffaele - Renieri, Leonardo - Bigliani, Claudia Rolla - Romoli, Michele - Sacco, Simona - Salmaggi, Andrea - Sangalli, Davide - Zini, Andrea - Doijiri, Ryosuke - Fukuda, Hiroki - Fujinaka, Toshiyuki - Fujita, Kyohei - Imamura, Hirotoshi - Sakai, Nobuyuki - Kanamaru, Takuya - Kimura, Naoto - Kono, Ryuhei - Miyake, Kosuke - Sakaguchi, Manabu - Sakai, Kenichiro - Sonoda, Kazutaka - Todo, Kenichi - Miyashita, Fumio - Tokuda, Naoki - Matsumaru, Yuji - Matsumoto, Shoji - Ohara, Nobuyuki - Shindo, Seigo - Takenobu, Yohei - Yoshimoto, Takeshi - Toyoda, Kazunori - Uwatoko, Takeshi - Yagita, Yoshiki et al. PY - 2023 TI - Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events A 1-Year Follow-up JF - Neurology VL - 100 IS - 4 SP - "E408"-"E421" EP - "E408"-"E421" PB - LIPPINCOTT WILLIAMS & WILKINS SN - 00283878 KW - COVID-19 Pandemic KW - Stroke Volumes KW - Cerebrovascular Events UR - https://n.neurology.org/content/100/4/e408 N2 - Background and Objectives Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020). Methods We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. Results There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1–6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1–4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4–5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6–0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31–1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82–2.97], 5,656/195,539) of all stroke hospitalizations. Discussion There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year. ER -
NGUYEN, Thanh N, Muhammad M QURESHI, Piers KLEIN, Hiroshi YAMAGAMI, Robert MIKULÍK, Anna CZLONKOWSKA, Mohamad ABDALKADER, Petra ŠEDOVÁ, Anvitha SATHYA, Hannah C LO, Ossama Yassin MANSOUR, Husitha Reddy VANGURU, Emilie LESAINE, Georgios TSIVGOULIS, Aaron I LOOCHTAN, Jelle DEMEESTERE, Ken UCHINO, Violiza INOA, Nitin GOYAL, Andreas CHARIDIMOU, James E SIEGLER, Shadi YAGHI, de Sousa Diana AGUIAR, Mahmoud H MOHAMMADEN, Diogo C HAUSSEN, Espen Saxhaug KRISTOFFERSEN, Virginia Pujol LEREIS, Sergio Daniel SCOLLO, Bruce C V CAMPBELL, Alice MA, James Orton THOMAS, Mark W PARSONS, Shaloo SINGHAL, Lee-Anne SLATER, Rodrigo Tomazini MARTINS, Chris ENZINGER, Thomas GATTRINGER, Aminur RAHMAN, Thomas BONNET, Noemie LIGOT, De Raedt SYLVIE, Robin LEMMENS, Peter VANACKER, Fenne VANDERVORST, Adriana Bastos CONFORTO, Raquel C T HIDALGO, Luciana de Oliveira NEVES, Rodrigo Targa MARTINS, Mora Cuervo Daissy LILIANA, Leticia C REBELLO, Igor Bessa SANTIAGO, da Silva Isabelle LAMEIRINHAS, Teodora SAKELAROVA, Rosen KALPACHKI, Filip ALEXIEV, Luciana CATANESE, Elena Adela CORA, Mayank GOYAL, Michael D HILL, Michael E KELLY, Houman KHOSRAVANI, Pascale LAVOIE, Lissa PEELING, Aleksandra PIKULA, Rodrigo RIVERA, Hui-Sheng CHEN, Yimin CHEN, Xiaochuan HUO, Zhongrong MIAO, Shuiquan YANG, Marina Roje BEDEKOVIC, Marina BRALIC, Hrvoje BUDINCEVIC, Angel Basilio CORREDOR-QUINTERO, Osvaldo E LARA-SARABIA, Martin CABAL, Dusan TENORA, Petr FIBRICH, Roman HERZIG, Emanuela HRABANOVSKA, David HLINOVSKY, Lubomir JURAK, Jana KADLCIKOVA, Igor KARPOWICZ, Lukas KLECKA, Martin KOVAR, David LAUER, Jiri NEUMANN, Hana PALOUSKOVA, Martin REISER, Petra REKOVA, Vladimir ROHAN, Ondrej SKODA, Miroslav ŠKORŇA, Martin SRAMEK, Lenka ZAKOVA, Hanne CHRISTENSEN, Nicolas DRENCK, Helle Klingenberg IVERSEN, Thomas Clement TRUELSEN, Troels WIENECKE, Khalid SOBH, Pauli YLIKOTILA, Kemal ALPAY, Daniel STRBIAN, Patricia BERNADY, Philippe CASENAVE, Maria DAN, Jean-Marc FAUCHEUX, Jean-Christophe GENTRIC, Elsa MAGRO, Candice SABBEN, Peggy REINER, Francois ROUANET, Ferdinand O BOHMANN, Stefan BOSKAMP, Joshua MBROH, Simon NAGEL, Christian H NOLTE, Peter A RINGLEB, Michael ROSENKRANZ, Sven POLI, Gotz THOMALLA, Theodoros KARAPANAYIOTIDES, Ioanna KOUTROULOU, Odysseas KARGIOTIS, Lina PALAIODIMOU, Barrientos Guerra Jose DOMINGUO, Vikram HUDED, Bindu MENON, Shashank NAGENDRA, Chintan PRAJAPATI, P N SYLAJA, Nyoman Angga Krishna PRAMANA, Achmad Firdaus SANI, Abdoreza GHOREISHI, Mehdi FARHOUDI, Elyar Sadeghi HOKMABADI, Abu Raya TARIQ, Shani Avnery KALMANOVICH, Levite RONEN, Sergiu Ionut SABETAY, Maurizio ACAMPA, Alessandro ADAMI, Lucio CASTELLAN, Marco LONGONI, Raffaele ORNELLO, Leonardo RENIERI, Claudia Rolla BIGLIANI, Michele ROMOLI, Simona SACCO, Andrea SALMAGGI, Davide SANGALLI, Andrea ZINI, Ryosuke DOIJIRI, Hiroki FUKUDA, Toshiyuki FUJINAKA, Kyohei FUJITA, Hirotoshi IMAMURA, Nobuyuki SAKAI, Takuya KANAMARU, Naoto KIMURA, Ryuhei KONO, Kosuke MIYAKE, Manabu SAKAGUCHI, Kenichiro SAKAI, Kazutaka SONODA, Kenichi TODO, Fumio MIYASHITA, Naoki TOKUDA, Yuji MATSUMARU, Shoji MATSUMOTO, Nobuyuki OHARA, Seigo SHINDO, Yohei TAKENOBU, Takeshi YOSHIMOTO, Kazunori TOYODA, Takeshi UWATOKO, Yoshiki YAGITA, Takehiro YAMADA, Nobuaki YAMAMOTO, Ryoo YAMAMOTO, Yukako YAZAWA, Yuri SUGIURA, Peter Kuria WAWERU, Jang-Hyun BAEK, Si Baek LEE, Kwon-Duk SEO, Sung-Il SOHN, Anita Ante ARSOVSKA, Yong Chieh CHAN, Wan Asyraf Wan ZAIDI, Ainul Syahrilfazli JAAFAR, Fernando GONGORA-RIVERA, Manuel MARTINEZ-MARINO, Adrian INFANTE-VALENZUELA, Stanislav GROPPA, Pavel LEAHU, Jonathan M COUTINHO, Leon A RINKEL, Diederik W J DIPPEL, Dianne H K VAN DAM-NOLEN, Annemarei RANTA, Teddy Y WU, Tajudeen Temitayo ADEBAYO, Abiodun H BELLO, Ernest Okwundu NWAZOR, Taofiki Ajao SUNMONU, Kolawole Wasiu WAHAB, Ole Morten RONNING, Else Charlotte SANDSET, Amal M AL HASHMI, Saima AHMAD, Umair RASHID, Liliana RODRIGUEZ-KADOTA, Patrick Matic YALUNG, Jon Stewart Hao DY, Maria Carissa PINEDA-FRANKS, Christian Oliver CO, Waldemar BROLA, Aleksander DEBIEC, Malgorzata DOROBEK, Michal Adam KARLINSKI, Beata M LABUZ-ROSZAK, Anetta LASEK-BAL, Halina SIENKIEWICZ-JAROSZ, Jacek STASZEWSKI, Piotr SOBOLEWSKI, Marcin WIACEK, Justyna ZIELINSKA-TUREK, Andre Pinho ARAUJO, Mariana ROCHA, Pedro CASTRO, Vitor Tedim CRUZ, Paulo Venancio FERREIRA, Patricia FERREIRA, Ana Paiva NUNES, Luisa FONSECA, Joao Pedro MARTO, Pinho e Melo TERESA, Miguel RODRIGUES, M Luis SILVA, Adela DIMITRIADE, Cristian FALUP-PECURARIU, May Adel HAMID, Narayanaswamy VENKETASUBRAMANIAN, Georgi KRASTEV, Miroslav MAKO, Oscar AYO-MARTIN, Francisco HERNANDEZ-FERANDEZ, Jordi BLASCO, Alejandro RODRIGUEZ-VAZQUEZ, Antonio CRUZ-CULEBRAS, Francisco MONICHE, Joan MONTANER, Soledad PEREZ-SANCHEZ, Garcia Sanchez Maria JESAS, Guillan Rodriguez MARTA, Katarina JOOD, Annika NORDANSTIG, Michael V MAZYA, Tiago T P MOREIRA, Gianmarco BERNAVA, Morin BEYELER, Manuel BOLOGNESE, Emmanuel CARRERA, Tomas DOBROCKY, Grzegorz Marek KARWACKI, Emanuela KELLER, Chang Yang HSIEH, Surawan BOONYAKARNKUL, Anchalee CHUROJANA, Ozlem AYKAC, Atilla Azcan OZDEMIR, Arsida BAJRAMI, Songul SENADIM, Syed Irteza HUSSAIN, Seby JOHN, Soma BANERJEE, Joseph KWAN, Kailash KRISHNAN, Robert LENTHALL, Ashok MATTHEWS, Ken WONG, Liqun ZHANG, Dorothea ALTSCHUL, Kaiz S ASIF, Zeelalem BAHIRU, Kristine BELOW, Sean RULAND, Saqib A CHAUDRY, Michael CHEN, Alex CHEBL, Jackie CIBULKA, Leon CISTRUNK, Judith CLARK, Marco COLASURDO, Alexandra CZAP, de Havenon ADAM, Salvatore AMATO, Sushrut DHARMADHIKARI, Kasey B GRIMMETT, Adam A DMYTRIW, Mark R ETHERTON, Chizoba EZEPUE, Mudassir FAROOQUI, Steven K FESKE, Lauren FINK, Ulviyya GASIMOVA, Amy K GUZIK, Maryam HAKEMI, Majesta HOVINGH, Muhib KHAN, Dinesh JILLELA, Rakesh KHATRI, Ayaz M KHAWAJA, Naim N KHOURY, Nicole L KILEY, Benny S KIM, Murali K KOLIKONDA, Anna Luisa KUHN, Stephanie LARA, Guillermo LINARES, Italo LINFANTE, Timothy G LUKOVITS, Sarah LYCAN, Shailesh S MALE, Laith MAALI, John MANCIN, Hesham MASOUD, Ghada A MOHAMED, Andre MONTEIRO, Fadi NAHAB, Krishna NALLEBALLE, Santiago ORTEGA-GUTIERREZ, Ajit S PURI, Yazan RADAIDEH, Rahul H RAHANGDALE, Ansaar RAI, Pankajavalli RAMAKRISHNAN, Aravind B REDDY, Diana M ROJAS-SOTO, Jose Rafael ROMERO, Natalia S ROST, Aaron ROTHSTEIN, Setareh Salehi OMRAN, Sunil A SHETH, Adnan H SIDDIQUI, Amy K STAROSCIAK, Nicholas E TARLOV, Robert A TAYLOR, Michael J WANG, Jared WOLFE, Ka-Ho WONG, Huynh Vu LE, Quy Viet NGUYEN, Thong Nhu PHAM, Trung Thanh NGUYEN, Hoang Thi PHAN, Mai Duy TON, Urs FISCHER, Patrik MICHEL, Davide STRAMBO, Sheila O MARTINS, Osama O ZAIDAT and Raul G NOGUEIRA. Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events A 1-Year Follow-up. \textit{Neurology}. Philadelphia: LIPPINCOTT WILLIAMS \&{} WILKINS, 2023, vol.~100, No~4, p.~''E408''-''E421'', 14 pp. ISSN~0028-3878. Available from: https://dx.doi.org/10.1212/WNL.0000000000201426.