Heterosis versus breakdown in cyprinid hybrids associated with
SVCV infection revealed by transcriptome profile analysis of
head kidney

J 2024

Heterosis versus breakdown in cyprinid hybrids associated with SVCV infection revealed by transcriptome profile analysis of head kidney

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea, Kristína KŘÍŽOVÁ, Kristýna VOŘÍŠKOVÁ, Lukáš VETEŠNÍK, Václav HEJRET et. al.

Basic information

Original name

Heterosis versus breakdown in cyprinid hybrids associated with SVCV infection revealed by transcriptome profile analysis of head kidney

Authors

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea (203 Czech Republic, guarantor, belonging to the institution), Kristína KŘÍŽOVÁ (703 Slovakia, belonging to the institution), Kristýna VOŘÍŠKOVÁ (203 Czech Republic, belonging to the institution), Lukáš VETEŠNÍK (203 Czech Republic, belonging to the institution), Václav HEJRET (203 Czech Republic, belonging to the institution), Lenka GETTOVÁ (703 Slovakia, belonging to the institution), Jiří VOREL (203 Czech Republic, belonging to the institution), Nikol RESLOVÁ (203 Czech Republic, belonging to the institution) and Vojtěch BYSTRÝ (203 Czech Republic, belonging to the institution)

Edition

Aquaculture, AMSTERDAM, ELSEVIER, 2024, 0044-8486

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10617 Marine biology, freshwater biology, limnology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.500 in 2022

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1016/j.aquaculture.2023.740083

UT WoS

001081360000001

Keywords in English

Cyprinids; Cyprinus carpio; Carassius gibelio; SVCV; Hybridization; Hybrid heterosis; Hybrid breakdown; Transcriptome profile analysis

Abstract

V originále

Whilst the hybrids of F1 generations usually experience heterosis for fitness-related traits (including the resistance to parasites), post-F1 generations, due to Dobzhansky-Muller genetic incompatibilities, express numerous disadvantageous traits (including susceptibility to parasites). Genetic disruption in hybrids may also result from the broken system of cyto-nuclear coadaptation. Maternal backcrosses (having parents with the same mtDNA) and paternal backcrosses (having parents with different mtDNA) have the same nuclear genetic compositions, but differ in cytoplasmic genetic elements, affecting their viability and survival.Spring viraemia of the carp virus (SVCV), a disease with a serious economic impact in aquacultures, affects almost exclusively cyprinids, primarily common carp (Cyprinus carpio), and causes high mortality, whilst gibel carp (Carassius gibelio) is a less susceptible species. Our study was focused on the transcriptome profile analysis of head kidney to reveal differential gene expression in highly susceptible common carp, weakly susceptible gibel carp, and hybrid lines, hypothetizing that the patterns of differential gene expression will reflect hybrid heterosis in F1 generations and hybrid breakdown in backcrosses and F2 generations. We expected the differences in differential gene expression between maternal and paternal backcrosses to be in line with the hypothesis of broken cyto-nuclear coadaptation.The pattern of differential gene expression revealed from the transcriptomic analysis of head kidney was linked to the resistance or susceptibility to SVCV infections in two pure species, C. gibelio and C. carpio, and their various generations of inter-specific hybrids. We evidenced hybrid heterosis for F1 generations of hybrids, mostly reflected by similarity in the down-regulation of differentially expressed genes classified within the viral infection disease category. High hybrid breakdown was documented throughout the transcriptomic analysis for paternal backcross generations and F2 generation of hybrids, confirming the broken system of cyto-nuclear coadaptation in those post-F1 generations. This evidence may support the role of intrinsic selection acting against inter-specific hybridization in freshwater fish.

Links

GA19-10088S, research and development project

Name: Genetická disrupce u mezidruhových hybridů kaprovitých ryb: její dopad na kondici-asociované znaky, imunitu a parazitární zátěž

Investor: Czech Science Foundation

Citovat

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea, Kristína KŘÍŽOVÁ, Kristýna VOŘÍŠKOVÁ, Lukáš VETEŠNÍK, Václav HEJRET, Lenka GETTOVÁ, Jiří VOREL, Nikol RESLOVÁ and Vojtěch BYSTRÝ. Heterosis versus breakdown in cyprinid hybrids associated with SVCV infection revealed by transcriptome profile analysis of head kidney. Aquaculture. AMSTERDAM: ELSEVIER, 2024, vol. 578, January, p. "740083", 14 pp. ISSN 0044-8486. Available from: https://dx.doi.org/10.1016/j.aquaculture.2023.740083.

@article{2333158,
   author = {Vetešníková Šimková, Andrea and Křížová, Kristína and Voříšková, Kristýna and Vetešník, Lukáš and Hejret, Václav and Gettová, Lenka and Vorel, Jiří and Reslová, Nikol and Bystrý, Vojtěch},
   article_location = {AMSTERDAM},
   article_number = {January},
   doi = {http://dx.doi.org/10.1016/j.aquaculture.2023.740083},
   keywords = {Cyprinids; Cyprinus carpio; Carassius gibelio; SVCV; Hybridization; Hybrid heterosis; Hybrid breakdown; Transcriptome profile analysis},
   language = {eng},
   issn = {0044-8486},
   journal = {Aquaculture},
   title = {Heterosis versus breakdown in cyprinid hybrids associated with SVCV infection revealed by transcriptome profile analysis of head kidney},
   url = {https://doi.org/10.1016/j.aquaculture.2023.740083},
   volume = {578},
   year = {2024}
}

TY  - JOUR
ID  - 2333158
AU  - Vetešníková Šimková, Andrea - Křížová, Kristína - Voříšková, Kristýna - Vetešník, Lukáš - Hejret, Václav - Gettová, Lenka - Vorel, Jiří - Reslová, Nikol - Bystrý, Vojtěch
PY  - 2024
TI  - Heterosis versus breakdown in cyprinid hybrids associated with SVCV infection revealed by transcriptome profile analysis of head kidney
JF  - Aquaculture
VL  - 578
IS  - January
SP  - "740083"
EP  - "740083"
PB  - ELSEVIER
SN  - 00448486
KW  - Cyprinids
KW  - Cyprinus carpio
KW  - Carassius gibelio
KW  - SVCV
KW  - Hybridization
KW  - Hybrid heterosis
KW  - Hybrid breakdown
KW  - Transcriptome profile analysis
UR  - https://doi.org/10.1016/j.aquaculture.2023.740083
N2  - Whilst the hybrids of F1 generations usually experience heterosis for fitness-related traits (including the resistance to parasites), post-F1 generations, due to Dobzhansky-Muller genetic incompatibilities, express numerous disadvantageous traits (including susceptibility to parasites). Genetic disruption in hybrids may also result from the broken system of cyto-nuclear coadaptation. Maternal backcrosses (having parents with the same mtDNA) and paternal backcrosses (having parents with different mtDNA) have the same nuclear genetic compositions, but differ in cytoplasmic genetic elements, affecting their viability and survival.Spring viraemia of the carp virus (SVCV), a disease with a serious economic impact in aquacultures, affects almost exclusively cyprinids, primarily common carp (Cyprinus carpio), and causes high mortality, whilst gibel carp (Carassius gibelio) is a less susceptible species. Our study was focused on the transcriptome profile analysis of head kidney to reveal differential gene expression in highly susceptible common carp, weakly susceptible gibel carp, and hybrid lines, hypothetizing that the patterns of differential gene expression will reflect hybrid heterosis in F1 generations and hybrid breakdown in backcrosses and F2 generations. We expected the differences in differential gene expression between maternal and paternal backcrosses to be in line with the hypothesis of broken cyto-nuclear coadaptation.The pattern of differential gene expression revealed from the transcriptomic analysis of head kidney was linked to the resistance or susceptibility to SVCV infections in two pure species, C. gibelio and C. carpio, and their various generations of inter-specific hybrids. We evidenced hybrid heterosis for F1 generations of hybrids, mostly reflected by similarity in the down-regulation of differentially expressed genes classified within the viral infection disease category. High hybrid breakdown was documented throughout the transcriptomic analysis for paternal backcross generations and F2 generation of hybrids, confirming the broken system of cyto-nuclear coadaptation in those post-F1 generations. This evidence may support the role of intrinsic selection acting against inter-specific hybridization in freshwater fish.
ER  -

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea, Kristína KŘÍŽOVÁ, Kristýna VOŘÍŠKOVÁ, Lukáš VETEŠNÍK, Václav HEJRET, Lenka GETTOVÁ, Jiří VOREL, Nikol RESLOVÁ and Vojtěch BYSTRÝ. Heterosis versus breakdown in cyprinid hybrids associated with SVCV infection revealed by transcriptome profile analysis of head kidney. \textit{Aquaculture}. AMSTERDAM: ELSEVIER, 2024, vol.~578, January, p.~''740083'', 14 pp. ISSN~0044-8486. Available from: https://dx.doi.org/10.1016/j.aquaculture.2023.740083.

Detailed Information on Publication Record