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@article{2338641, author = {Križanová, Oľga and Penesova, Adela and Hokynková, Alica and Pokorná, Andrea and Samadian, Amir and Babula, Petr}, article_location = {Hoboken}, article_number = {2}, doi = {http://dx.doi.org/10.1111/iwj.14405}, keywords = {chronic venous insufficiency; compression therapy; therapy; venous leg ulcers; wound coverage}, language = {eng}, issn = {1742-4801}, journal = {International Wound Journal}, title = {Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment}, url = {https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.14405}, volume = {21}, year = {2024} }
TY - JOUR ID - 2338641 AU - Križanová, Oľga - Penesova, Adela - Hokynková, Alica - Pokorná, Andrea - Samadian, Amir - Babula, Petr PY - 2024 TI - Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment JF - International Wound Journal VL - 21 IS - 2 SP - 1-9 EP - 1-9 PB - Wiley-Blackwell SN - 17424801 KW - chronic venous insufficiency KW - compression therapy KW - therapy KW - venous leg ulcers KW - wound coverage UR - https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.14405 N2 - The chronic venous disease covers a wide spectrum of venous disorders that are characterized by severely impaired blood return that primarily affects veins in the lower extremities. Morphological and functional abnormalities of the venous system led to chronic venous insufficiency (CVI), and present as leg heaviness/achiness, edema, telangiectasia, and varices. The term 'chronic venous insufficiency' (CVI) refers to a disease of greater severity. Venous dysfunction is associated with venous hypertension and is associated with venous reflux due to poorly functioning or incompetent venous valves, which ultimately reduces venous return, leading to a cascade of morphological, physiological, and histologic abnormalities such as blood pooling, hypoxia, inflammation, swelling, skin changes (lipodermatosclerosis), and in severe cases, venous leg ulcers (VLU). This review summarizes recent knowledge about the aetiology, risk factors, and pathophysiology of VLU and compared the possibilities of their treatment. ER -
KRIŽANOVÁ, Oľga, Adela PENESOVA, Alica HOKYNKOVÁ, Andrea POKORNÁ, Amir SAMADIAN and Petr BABULA. Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment. \textit{International Wound Journal}. Hoboken: Wiley-Blackwell, 2024, vol.~21, No~2, p.~1-9. ISSN~1742-4801. Available from: https://dx.doi.org/10.1111/iwj.14405.
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