Chronic venous insufficiency and venous leg ulcers: Aetiology,
on the pathophysiology-based treatment

J 2024

Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment

KRIŽANOVÁ, Oľga, Adela PENESOVA, Alica HOKYNKOVÁ, Andrea POKORNÁ, Amir SAMADIAN et. al.

Basic information

Original name

Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment

Authors

KRIŽANOVÁ, Oľga (703 Slovakia, belonging to the institution), Adela PENESOVA (703 Slovakia), Alica HOKYNKOVÁ (703 Slovakia, belonging to the institution), Andrea POKORNÁ (203 Czech Republic, belonging to the institution), Amir SAMADIAN (364 Islamic Republic of Iran, belonging to the institution) and Petr BABULA (203 Czech Republic, guarantor, belonging to the institution)

Edition

International Wound Journal, Hoboken, Wiley-Blackwell, 2024, 1742-4801

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30216 Dermatology and venereal diseases

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.100 in 2022

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1111/iwj.14405

UT WoS

001085543900001

Keywords in English

chronic venous insufficiency; compression therapy; therapy; venous leg ulcers; wound coverage

Abstract

V originále

The chronic venous disease covers a wide spectrum of venous disorders that are characterized by severely impaired blood return that primarily affects veins in the lower extremities. Morphological and functional abnormalities of the venous system led to chronic venous insufficiency (CVI), and present as leg heaviness/achiness, edema, telangiectasia, and varices. The term 'chronic venous insufficiency' (CVI) refers to a disease of greater severity. Venous dysfunction is associated with venous hypertension and is associated with venous reflux due to poorly functioning or incompetent venous valves, which ultimately reduces venous return, leading to a cascade of morphological, physiological, and histologic abnormalities such as blood pooling, hypoxia, inflammation, swelling, skin changes (lipodermatosclerosis), and in severe cases, venous leg ulcers (VLU). This review summarizes recent knowledge about the aetiology, risk factors, and pathophysiology of VLU and compared the possibilities of their treatment.

Links

NU21-09-00541, research and development project

Name: Role oxidativního stresu při hojení dekubitů u pacientů s míšní lézí

Investor: Ministry of Health of the CR, Subprogram 1 - standard

Citovat

KRIŽANOVÁ, Oľga, Adela PENESOVA, Alica HOKYNKOVÁ, Andrea POKORNÁ, Amir SAMADIAN and Petr BABULA. Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment. International Wound Journal. Hoboken: Wiley-Blackwell, 2024, vol. 21, No 2, p. 1-9. ISSN 1742-4801. Available from: https://dx.doi.org/10.1111/iwj.14405.

@article{2338641,
   author = {Križanová, Oľga and Penesova, Adela and Hokynková, Alica and Pokorná, Andrea and Samadian, Amir and Babula, Petr},
   article_location = {Hoboken},
   article_number = {2},
   doi = {http://dx.doi.org/10.1111/iwj.14405},
   keywords = {chronic venous insufficiency; compression therapy; therapy; venous leg ulcers; wound coverage},
   language = {eng},
   issn = {1742-4801},
   journal = {International Wound Journal},
   title = {Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment},
   url = {https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.14405},
   volume = {21},
   year = {2024}
}

TY  - JOUR
ID  - 2338641
AU  - Križanová, Oľga - Penesova, Adela - Hokynková, Alica - Pokorná, Andrea - Samadian, Amir - Babula, Petr
PY  - 2024
TI  - Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment
JF  - International Wound Journal
VL  - 21
IS  - 2
SP  - 1-9
EP  - 1-9
PB  - Wiley-Blackwell
SN  - 17424801
KW  - chronic venous insufficiency
KW  - compression therapy
KW  - therapy
KW  - venous leg ulcers
KW  - wound coverage
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.14405
N2  - The chronic venous disease covers a wide spectrum of venous disorders that are characterized by severely impaired blood return that primarily affects veins in the lower extremities. Morphological and functional abnormalities of the venous system led to chronic venous insufficiency (CVI), and present as leg heaviness/achiness, edema, telangiectasia, and varices. The term 'chronic venous insufficiency' (CVI) refers to a disease of greater severity. Venous dysfunction is associated with venous hypertension and is associated with venous reflux due to poorly functioning or incompetent venous valves, which ultimately reduces venous return, leading to a cascade of morphological, physiological, and histologic abnormalities such as blood pooling, hypoxia, inflammation, swelling, skin changes (lipodermatosclerosis), and in severe cases, venous leg ulcers (VLU). This review summarizes recent knowledge about the aetiology, risk factors, and pathophysiology of VLU and compared the possibilities of their treatment.
ER  -

KRIŽANOVÁ, Oľga, Adela PENESOVA, Alica HOKYNKOVÁ, Andrea POKORNÁ, Amir SAMADIAN and Petr BABULA. Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment. \textit{International Wound Journal}. Hoboken: Wiley-Blackwell, 2024, vol.~21, No~2, p.~1-9. ISSN~1742-4801. Available from: https://dx.doi.org/10.1111/iwj.14405.

Detailed Information on Publication Record