J 2023

Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley

BOBALOVA, Janette, Dana STROUHALOVA a Pavel BOBÁĽ

Základní údaje

Originální název

Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley

Autoři

BOBALOVA, Janette (garant), Dana STROUHALOVA a Pavel BOBÁĽ (703 Slovensko, domácí)

Vydání

Journal of Agricultural and Food Chemistry, WASHINGTON, AMER CHEMICAL SOC, 2023, 0021-8561

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.100 v roce 2022

Kód RIV

RIV/00216224:14160/23:00132279

Organizační jednotka

Farmaceutická fakulta

DOI

http://dx.doi.org/10.1021/acs.jafc.3c00886

UT WoS

001079010800001

Klíčová slova anglicky

barley; post-translationalmodification; protein; mass spectrometry

Štítky

rivok, ÚChL

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 15. 11. 2023 15:21, JUDr. Sabina Krejčiříková

Anotace

V originále

Post-translational modifications (PTMs) of biomacromolecules can be useful for understanding the processes by which a relatively small number of individual genes in a particular genome can generate enormous biological complexity in different organisms. The proteomes of barley and the brewing process were investigated by different techniques. However, their diverse and complex PTMs remain understudied. As standard analytical approaches have limitations, innovative analytical approaches need to be developed and applied in PTM studies. To make further progress in this field, it is necessary to specify the sites of modification, as well as to characterize individual isoforms with increased selectivity and sensitivity. This review summarizes advances in the PTM analysis of barley proteins, particularly those involving mass spectrometric detection. Our focus is on monitoring phosphorylation, glycation, and glycosylation, which critically influence functional behavior in metabolism and regulation in organisms.
Zobrazeno: 31. 10. 2024 12:17