Common Post-translational Modifications (PTMs) of Proteins:
Analysis by Up-to-Date Analytical Techniques with an Emphasis
on Barley

J 2023

Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley

BOBALOVA, Janette, Dana STROUHALOVA and Pavel BOBÁĽ

Basic information

Original name

Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley

Authors

BOBALOVA, Janette (guarantor), Dana STROUHALOVA and Pavel BOBÁĽ (703 Slovakia, belonging to the institution)

Edition

Journal of Agricultural and Food Chemistry, WASHINGTON, AMER CHEMICAL SOC, 2023, 0021-8561

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 6.100 in 2022

RIV identification code

RIV/00216224:14160/23:00132279

Organization unit

Faculty of Pharmacy

DOI

http://dx.doi.org/10.1021/acs.jafc.3c00886

UT WoS

001079010800001

Keywords in English

barley; post-translationalmodification; protein; mass spectrometry

Abstract

V originále

Post-translational modifications (PTMs) of biomacromolecules can be useful for understanding the processes by which a relatively small number of individual genes in a particular genome can generate enormous biological complexity in different organisms. The proteomes of barley and the brewing process were investigated by different techniques. However, their diverse and complex PTMs remain understudied. As standard analytical approaches have limitations, innovative analytical approaches need to be developed and applied in PTM studies. To make further progress in this field, it is necessary to specify the sites of modification, as well as to characterize individual isoforms with increased selectivity and sensitivity. This review summarizes advances in the PTM analysis of barley proteins, particularly those involving mass spectrometric detection. Our focus is on monitoring phosphorylation, glycation, and glycosylation, which critically influence functional behavior in metabolism and regulation in organisms.

Citovat

BOBALOVA, Janette, Dana STROUHALOVA and Pavel BOBÁĽ. Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley. Journal of Agricultural and Food Chemistry. WASHINGTON: AMER CHEMICAL SOC, 2023, vol. 71, No 41, p. 14825-14837. ISSN 0021-8561. Available from: https://dx.doi.org/10.1021/acs.jafc.3c00886.

@article{2339698,
   author = {Bobalova, Janette and Strouhalova, Dana and Bobáľ, Pavel},
   article_location = {WASHINGTON},
   article_number = {41},
   doi = {http://dx.doi.org/10.1021/acs.jafc.3c00886},
   keywords = {barley; post-translationalmodification; protein; mass spectrometry},
   language = {eng},
   issn = {0021-8561},
   journal = {Journal of Agricultural and Food Chemistry},
   title = {Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley},
   url = {https://pubs.acs.org/doi/10.1021/acs.jafc.3c00886},
   volume = {71},
   year = {2023}
}

TY  - JOUR
ID  - 2339698
AU  - Bobalova, Janette - Strouhalova, Dana - Bobáľ, Pavel
PY  - 2023
TI  - Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley
JF  - Journal of Agricultural and Food Chemistry
VL  - 71
IS  - 41
SP  - 14825-14837
EP  - 14825-14837
PB  - AMER CHEMICAL SOC
SN  - 00218561
KW  - barley
KW  - post-translationalmodification
KW  - protein
KW  - mass spectrometry
UR  - https://pubs.acs.org/doi/10.1021/acs.jafc.3c00886
N2  - Post-translational modifications (PTMs) of biomacromolecules can be useful for understanding the processes by which a relatively small number of individual genes in a particular genome can generate enormous biological complexity in different organisms. The proteomes of barley and the brewing process were investigated by different techniques. However, their diverse and complex PTMs remain understudied. As standard analytical approaches have limitations, innovative analytical approaches need to be developed and applied in PTM studies. To make further progress in this field, it is necessary to specify the sites of modification, as well as to characterize individual isoforms with increased selectivity and sensitivity. This review summarizes advances in the PTM analysis of barley proteins, particularly those involving mass spectrometric detection. Our focus is on monitoring phosphorylation, glycation, and glycosylation, which critically influence functional behavior in metabolism and regulation in organisms.
ER  -

BOBALOVA, Janette, Dana STROUHALOVA and Pavel BOBÁĽ. Common Post-translational Modifications (PTMs) of Proteins: Analysis by Up-to-Date Analytical Techniques with an Emphasis on Barley. \textit{Journal of Agricultural and Food Chemistry}. WASHINGTON: AMER CHEMICAL SOC, 2023, vol.~71, No~41, p.~14825-14837. ISSN~0021-8561. Available from: https://dx.doi.org/10.1021/acs.jafc.3c00886.

Detailed Information on Publication Record