Endemic parkinsonism: clusters, biology and clinical features

J 2023

Endemic parkinsonism: clusters, biology and clinical features

MENSIKOVA, Katerina, John C STEELE, Raymond ROSALES, Carlo COLOSIMO, Peter SPENCER et. al.

Basic information

Original name

Endemic parkinsonism: clusters, biology and clinical features

Authors

MENSIKOVA, Katerina (203 Czech Republic), John C STEELE, Raymond ROSALES, Carlo COLOSIMO, Peter SPENCER, Annie LANNUZEL, Yoshikazu UGAWA, Ryogen SASAKI, Santiago GIMENEZ-ROLDAN, Radoslav MATEJ (203 Czech Republic), Lucie TUCKOVA (203 Czech Republic), Dominik HRABOS (203 Czech Republic), Kristyna KOLARIKOVA (203 Czech Republic), Radek VODICKA (203 Czech Republic), Radek VRTEL (203 Czech Republic), Miroslav STRNAD (203 Czech Republic), Petr HLUSTIK (203 Czech Republic), Pavel OTRUBA (203 Czech Republic), Martin PROCHAZKA (203 Czech Republic), Martin BAREŠ (203 Czech Republic, belonging to the institution), Susana BOLUDA, Luc BUEE, Gerhard RANSMAYR and Petr KANOVSKY (203 Czech Republic, guarantor)

Edition

NATURE REVIEWS NEUROLOGY, Berlin, NATURE PORTFOLIO, 2023, 1759-4758

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 38.100 in 2022

RIV identification code

RIV/00216224:14110/23:00132289

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1038/s41582-023-00866-3

UT WoS

001061908600001

Keywords in English

endemic parkinsonism:

Abstract

V originále

The term 'endemic parkinsonism' refers to diseases that manifest with a dominant parkinsonian syndrome, which can be typical or atypical, and are present only in a particular geographically defined location or population. Ten phenotypes of endemic parkinsonism are currently known: three in the Western Pacific region; two in the Asian-Oceanic region; one in the Caribbean islands of Guadeloupe and Martinique; and four in Europe. Some of these disease entities seem to be disappearing over time and therefore are probably triggered by unique environmental factors. By contrast, other types persist because they are exclusively genetically determined. Given the geographical clustering and potential overlap in biological and clinical features of these exceptionally interesting diseases, this Review provides a historical reference text and offers current perspectives on each of the 10 phenotypes of endemic parkinsonism. Knowledge obtained from the study of these disease entities supports the hypothesis that both genetic and environmental factors contribute to the development of neurodegenerative diseases, not only in endemic parkinsonism but also in general. At the same time, this understanding suggests useful directions for further research in this area.

Citovat

MENSIKOVA, Katerina, John C STEELE, Raymond ROSALES, Carlo COLOSIMO, Peter SPENCER, Annie LANNUZEL, Yoshikazu UGAWA, Ryogen SASAKI, Santiago GIMENEZ-ROLDAN, Radoslav MATEJ, Lucie TUCKOVA, Dominik HRABOS, Kristyna KOLARIKOVA, Radek VODICKA, Radek VRTEL, Miroslav STRNAD, Petr HLUSTIK, Pavel OTRUBA, Martin PROCHAZKA, Martin BAREŠ, Susana BOLUDA, Luc BUEE, Gerhard RANSMAYR and Petr KANOVSKY. Endemic parkinsonism: clusters, biology and clinical features. NATURE REVIEWS NEUROLOGY. Berlin: NATURE PORTFOLIO, 2023, vol. 19, No 10, p. 599-616. ISSN 1759-4758. Available from: https://dx.doi.org/10.1038/s41582-023-00866-3.

@article{2339918,
   author = {Mensikova, Katerina and Steele, John C and Rosales, Raymond and Colosimo, Carlo and Spencer, Peter and Lannuzel, Annie and Ugawa, Yoshikazu and Sasaki, Ryogen and GimenezandRoldan, Santiago and Matej, Radoslav and Tuckova, Lucie and Hrabos, Dominik and Kolarikova, Kristyna and Vodicka, Radek and Vrtel, Radek and Strnad, Miroslav and Hlustik, Petr and Otruba, Pavel and Prochazka, Martin and Bareš, Martin and Boluda, Susana and Buee, Luc and Ransmayr, Gerhard and Kanovsky, Petr},
   article_location = {Berlin},
   article_number = {10},
   doi = {http://dx.doi.org/10.1038/s41582-023-00866-3},
   keywords = {endemic parkinsonism:},
   language = {eng},
   issn = {1759-4758},
   journal = {NATURE REVIEWS NEUROLOGY},
   title = {Endemic parkinsonism: clusters, biology and clinical features},
   url = {https://www.nature.com/articles/s41582-023-00866-3},
   volume = {19},
   year = {2023}
}

TY  - JOUR
ID  - 2339918
AU  - Mensikova, Katerina - Steele, John C - Rosales, Raymond - Colosimo, Carlo - Spencer, Peter - Lannuzel, Annie - Ugawa, Yoshikazu - Sasaki, Ryogen - Gimenez-Roldan, Santiago - Matej, Radoslav - Tuckova, Lucie - Hrabos, Dominik - Kolarikova, Kristyna - Vodicka, Radek - Vrtel, Radek - Strnad, Miroslav - Hlustik, Petr - Otruba, Pavel - Prochazka, Martin - Bareš, Martin - Boluda, Susana - Buee, Luc - Ransmayr, Gerhard - Kanovsky, Petr
PY  - 2023
TI  - Endemic parkinsonism: clusters, biology and clinical features
JF  - NATURE REVIEWS NEUROLOGY
VL  - 19
IS  - 10
SP  - 599-616
EP  - 599-616
PB  - NATURE PORTFOLIO
SN  - 17594758
KW  - endemic parkinsonism:
UR  - https://www.nature.com/articles/s41582-023-00866-3
N2  - The term 'endemic parkinsonism' refers to diseases that manifest with a dominant parkinsonian syndrome, which can be typical or atypical, and are present only in a particular geographically defined location or population. Ten phenotypes of endemic parkinsonism are currently known: three in the Western Pacific region; two in the Asian-Oceanic region; one in the Caribbean islands of Guadeloupe and Martinique; and four in Europe. Some of these disease entities seem to be disappearing over time and therefore are probably triggered by unique environmental factors. By contrast, other types persist because they are exclusively genetically determined. Given the geographical clustering and potential overlap in biological and clinical features of these exceptionally interesting diseases, this Review provides a historical reference text and offers current perspectives on each of the 10 phenotypes of endemic parkinsonism. Knowledge obtained from the study of these disease entities supports the hypothesis that both genetic and environmental factors contribute to the development of neurodegenerative diseases, not only in endemic parkinsonism but also in general. At the same time, this understanding suggests useful directions for further research in this area.
ER  -

MENSIKOVA, Katerina, John C STEELE, Raymond ROSALES, Carlo COLOSIMO, Peter SPENCER, Annie LANNUZEL, Yoshikazu UGAWA, Ryogen SASAKI, Santiago GIMENEZ-ROLDAN, Radoslav MATEJ, Lucie TUCKOVA, Dominik HRABOS, Kristyna KOLARIKOVA, Radek VODICKA, Radek VRTEL, Miroslav STRNAD, Petr HLUSTIK, Pavel OTRUBA, Martin PROCHAZKA, Martin BAREŠ, Susana BOLUDA, Luc BUEE, Gerhard RANSMAYR and Petr KANOVSKY. Endemic parkinsonism: clusters, biology and clinical features. \textit{NATURE REVIEWS NEUROLOGY}. Berlin: NATURE PORTFOLIO, 2023, vol.~19, No~10, p.~599-616. ISSN~1759-4758. Available from: https://dx.doi.org/10.1038/s41582-023-00866-3.

Detailed Information on Publication Record